Production of Fibrinolytic Enzyme by Streptomyces
Rimosus at Conditions of Nitrogen Limitation |
| Victoria Gesheva* |
| Stephan Angeloff Institute of Microbiogy, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria |
| *Corresponding author: |
Dr. Victoria Gesheva,
Stephan Angeloff Institute
of Microbiogy,
Bulgarian Academy of Sciences, Sofia 1113, Bulgaria,
E-mail : teteven@excite.com. |
|
| Received December 08, 2009; Accepted December 24, 2009; Published December 24, 2009 |
Citation: Gesheva V (2009) Production of Fibrinolytic Enzyme by Streptomyces Rimosus at Conditions of Nitrogen Limitation. J Microbial Biochem Technol 1: 057-058. doi:10.4172/1948-5948.1000011 |
Copyright: © 2009 Gesheva V. This is an open-access article distributed
under the terms of the Creative Commons Attribution License,which
permits unrestricted use, distribution, and reproduction in any medium,
provided the original author and source are credited. |
| Abstract |
The kinetic of the enzyme production of Streptomyces
rimosus, a producer of exoproteases was investigated
in conditions of nitrogen limitation.The maxima of fibrinolytic
and caseinolytic activities by Streptomyces
rimosus were reached at 84 h, respectively 96 h. Values
of activities were increased 5-fold with those on initial
medium. The ultrastructure changes were followed. In
the earlier hours an aggregation of ribosomes in cells
was established. Large membranes and numerous electron-
transparent structures were found. The obtained results
indicated close connection between cell status of
the producer, its enzyme productivity and an ability of
the strain to survive at conditions of nitrogen limitation. |
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