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Progress on the Long Non-coding RNAs Involved in Alzheimer’s Disease
Alzheimer’s Disease (AD) is terminal and is considered the most common neurodegenerative disease characterized by progressive memory loss and cognitive impairment, accounting for 60% of all dementia cases. AD has been widely studied, but its pathological mechanism is still unclear. Noncoding RNAs (ncRNAs) are a class of RN.. Read More
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A Case Report and Literature Review on Rare LMO7-ALK Rearrangement in Lung Adenocarcinoma
Background: In non-small cell lung cancer (NSCLC), anaplastic lymphoma kinase (ALK) gene rearrangement is a critical therapeutic biomarker. Partner LMO7 gene was discovered in patients with NSCLC fused to ALK gene as reported (L15: A20), (L16: A20). Investigating the relationship between various breakpoints and prognosis was sig.. Read More
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Polymerase Chain Reaction (PCR): Revolutionizing Molecular Biology
Polymerase Chain Reaction (PCR) has emerged as a transformative force in molecular biology, reshaping research methodologies and expanding our capabilities in understanding, analyzing, and manipulating DNA. Developed by Kary B. Mullis in 1983, PCR has become an indispensable tool for amplifying specific DNA sequences, enabling e.. Read More
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Genetic Engineering: Unraveling the Potential, Ethical Dilemmas, and Future Implications
stract Genetic engineering stands as a transformative force at the crossroads of biology and technology, showcasing remarkable advancements with far-reaching implications. This research article delves into the multifaceted realm of genetic engineering, unraveling its potential, navigating ethical dilemmas, and forecasting future.. Read More
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Decoding the Molecular Symphony: An In-Depth Exploration of Gene Expression
Gene expression, the intricate orchestration of genetic information into functional molecules, lies at the heart of cellular processes, orchestrating the symphony of life. This research article embarks on a comprehensive journey into the dynamic landscape of gene expression, elucidating its profound impact on cellular biology an.. Read More
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Decoding the Molecular Dance: Unraveling the Intricacies of Protein Synthesis
Protein synthesis, often referred to as the "Molecular Dance," is a fundamental biological process essential for the maintenance, growth, and repair of living organisms. This intricate cellular ballet involves the transformation of genetic information encoded in DNA into functional proteins, which serve as the structural and fun.. Read More
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RNA Transcription: Unraveling the Molecular Symphony of Genetic Expression
RNA transcription is a fundamental process in molecular biology that plays a pivotal role in the expression of genetic information. This research article explores the intricate mechanisms and regulatory factors involved in RNA transcription, shedding light on its significance in cellular functions and the broader context of gene.. Read More
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Understanding the Complex Mechanisms of DNA Replication: A Comprehensive Review
DNA replication is a fundamental process crucial for the transmission of genetic information from one generation to the next. This intricate mechanism ensures the faithful duplication of the genetic material, maintaining the integrity and stability of the genome. This research article aims to provide a comprehensive overview of .. Read More
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LncRNA Microarray Analysis of Non-small Cell Lung Cancer A549 Cell Lines Treated with Phycocyanin
Phycocyanin is a type of marine food additive with multiple biological properties, including anticancer activity, but its underlying antineoplastic mechanism in non-small cell lung cancer (NSCLC) remains unclear. To investigate the underlying regulatory mechanism of phycocyanin in NSCLC, an LncRNA microarray analysis was perform.. Read More
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We investigated the effect of Sodium valproate (VAP) combined with methylprednisolone (MP) on spinal cord injury (SCI), and its underlying mechanism. Following the establishment of the SCI model using SD mice, VPA treatment group: 8 hours after the establishment of SCI model, VAP (dissolved in normal saline) was injected intrape.. Read More
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Background: Anti-angiogenic therapies and immunotherapy are pivotal treatment options for kidney renal clear cell carcinoma (KIRC). However, the role of angiogenesis-associated genes (AAGs) in tumorigenesis of renal cell carcinoma, their potential as prognostic markers, impact on the tumor microenvironment (TME), and response to.. Read More
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A Method of Screening for Trisomy 18 by Detecting Amniotic Fluid Punctures
Objective: We aimed to develop a new method of screening for Trisomy 18 by detecting amniotic fluid punctures to complement the current methods. Method: Two commercially available genomic DNA extracted from the amniotic fluid puncture of the pregnant woman with the Trisomy 18 fetus, two genomic DNAs extracted from two healthy m.. Read More
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Advancements in Methods and Techniques in Molecular Biology: A Comprehensive Review
Molecular biology, a dynamic field at the intersection of biology and technology, has undergone a paradigm shift propelled by groundbreaking advancements in methods and techniques. This comprehensive review navigates through the intricacies of contemporary molecular biology, shedding light on the transformative tools that have r.. Read More
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Advancements in Molecular Genetics: Unraveling the Code of Life
Molecular genetics stands at the forefront of scientific inquiry, continuously pushing the boundaries of our understanding of the genetic underpinnings of life. This research article explores the recent strides made in the field, delving into the intricacies of molecular mechanisms governing the code of life. From the foundation.. Read More
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Advancements in Computational Biology: Unraveling the Mysteries of Life
In the realm of scientific exploration, the field of Computational Biology has emerged as a pivotal force, seamlessly integrating the power of computational methodologies with the intricacies of biological phenomena. This article delves into the profound advancements that have shaped the landscape of Computational Biology, provi.. Read More
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Advancements in Stem Cell Regeneration: A Comprehensive Review
Stem cell regeneration stands at the forefront of transformative medical research, offering unparalleled possibilities for treating a myriad of diseases and injuries. This comprehensive review delves into the dynamic landscape of stem cell regeneration, encompassing breakthroughs, hurdles, and future trajectories. The study navi.. Read More
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Exploring the Complexity of Biological Systems: A Comprehensive Review
This comprehensive review delves into the intricate world of biology, aiming to unravel the complexities that govern living organisms. From the microscopic structures within cells to the vast ecosystems that span the globe, biology encompasses a diverse array of processes and interactions. The exploration begins at the molecular.. Read More
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Advancements in Cellular DNA Studies: Unraveling the Secrets of the Blueprint of Life
Cellular DNA studies have been integral to the progression of biological research, providing profound insights into the fundamental mechanisms governing life. From the foundational elucidation of the DNA double helix structure to contemporary breakthroughs in high-throughput sequencing and genome editing technologies, this resea.. Read More
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Advancements in Molecular Biotechnology: Unveiling the Future of Precision Medicine and Beyond
Advancements in molecular biotechnology have ushered in a transformative era in the realms of medicine, agriculture, and industry. This research article unveils the current state and future prospects of this dynamic field, emphasizing its profound impact on precision medicine and beyond. Beginning with a historical overview, the.. Read More
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Fission yeast (Schizosaccharomyces pombe) is used as a platform for analyzing the activity of heterologous G protein-coupled receptors (GPCR). This type of yeast has two GPCR systems; one for detecting pheromones, and another for detecting glucose. We previously reported on a green fluorescent protein (GFP) reporter system in fi.. Read More
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