ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

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Andreas Schulze

Andreas Schulze

Genetics and Genome Biology

University of Toronto

Canada

Biography

Dr. Andreas Schulze is a Director, Newborn Screening Program Clinical and Metabolic Genetics and Associate Scientist in Department of Genetics & Genome Biology at University of Toronto his Research Interests Genetic Diseases of Creatine Metabolism. Improving strategies for early diagnosis and treatment in genetic defects of guanidinoacetate methyltransferase (GAMT), arginine: glycine amidinotransferase (AGAT) and creatine transporter (CrT1). My research suggests that early and efficient treatment may prevent severe neurological impairment in patients. My research goal is to develop comprehensive biochemical and molecular genetic testing and inclusion in newborn screening. Through my research I plan to optimize existing, and develop new treatments to improve brain creatine uptake and to reduce neurotoxic guanidinoacetate. I will also continue to study AGAT and GAMT knock-out mice and development of a model for the CRT defect.

 

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