Plasmapheresis in Organophosphorus Poisoning – Intensive Management and its Successful Use

Dec 30, 2011 by Journal of Clinical Toxicology

Management of Organophosphorus poisoning can be difficult at times, especially when there is no history of poisoning or where the compound is not known to begin with & which is compounded by the absence of odour. Plasmapheresis has been tried effectively in toxicology in the treatment of various toxic substances ingestion, and can replace circulating cholinesterase in these patients with organophosphate poisoning. We report a case of young boy who initially presented with unknown compound poisoning, but subsequently had clinical features of organophosphorus poisoning alongwith reduced levels of acetyl cholinesterase, managed by plasmapheresis.