Cancer Medicine & Anti Cancer Drugs
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Editorial Board

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Junming Yue
University of Tennessee Health Science Center
USA

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Myron R Szewczuk
Queen’s University
Canada

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Sujeeve Jeganathan
University Health Network
Ontario

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About the Journal

The Journal of Cancer Medicine and Anticancer Drugs is a peer-reviewed medical journal in cancer biology. This Scientific Journal focuses on the recognition of cellular responses to DNA damage, apoptosis (cell death), and inactivation of tumor suppressor genes and analysis of carcinogenic process by genetic and epigenetic alterations in genes for the study of cancer initiation and progression. Anticancer drugs are used to control the growth of cancerous cells. Cancer is commonly defined as the uncontrolled growth of cells, with loss of differentiation and commonly, with metastasis, spread of the cancer to other tissues and organs. Cancers are malignant growths. In contrast, benign growths remain encapsulated and grow within a well-defined area. Although benign tumors may be fatal if untreated, due to pressure on essential organs, as in the case of a benign brain tumor, surgery or radiation are the preferred methods of treating growths which have a well-defined location. Drug therapy is used when the tumor has spread, or may spread, to all areas of the body.

Journal of Cancer Medicine and Anticancer Drugs provides a unique forum for interaction and dissemination of original research and educational information relevant to the practice of Cancer Medicine and Anticancer Drugs and its related oncologic disciplines. The journal strives to have a positive effect on cancer prevention, early detection, diagnosis, and cure by the publication of high-quality content. The mission of Cancer Medicine and Anticancer Drugs is to present and inform readers of new applications, technological advances, cutting-edge research, novel applications of molecular techniques, and relevant review articles related to Cancer Medicine.

Cancer medicine is one of the best open access journals that aims to publish the most complete and reliable source of information on discoveries and current developments in the mode of Original articles, Review articles, Case reports, Short communications, etc. in the field and provides free online access to the researchers worldwide.

This scholarly open access journal is using Editorial Manager System for online manuscript submission, review and the progress of the article. Editorial board members of Journal of Cancer medicine and Anticancer drugs or outside experts review manuscripts; at least two independent reviewer’s approval followed by the editor is required for the acceptance of any citable manuscript.

Chemotherapy

Chemotherapy (also called chemo) is a type of cancer treatment that uses drugs to destroy cancer cells. Chemotherapy works by stopping or slowing the growth of cancer cells, which grow and divide quickly. But it can also harm healthy cells that divide quickly, such as those that line your mouth and intestines or cause your hair to grow. Damage to healthy cells may cause side effects. Often, side effects get better or go away after chemotherapy is over.

Related journals of  Chemotherapy

Cancer Medicine & Anti Cancer Drugs, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Journal of Carcinogenesis & Mutagenesis, Journal of Brain Tumors & Neurooncology, Nature Reviews Cancer, Cancer Cell, Journal of Clinical Oncology, Cell Host and Microbe, PLoS Genetics, Journal of the National Cancer Institute, Cancer Research, Clinical Cancer Research.

Avastin

Avastin (bevacizumab) is a cancer medication that interferes with the growth and spread of cancer cells in the body. It is used to treat a certain type of brain tumor, and certain types of cancers of the kidney, lung, colon, rectum, cervix, ovary, or fallopian tube. Avastin is also used to treat cancer of the membrane lining the internal organs in your abdomen It is usually given as part of a combination of cancer medicines. Avastin (bevacizumab) is a recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF) in in vitro and in vivo assay systems.

Related journals of  Avastin

Cancer Medicine & Anti Cancer Drugs, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Journal of Carcinogenesis & Mutagenesis, Journal of Brain Tumors & Neurooncology, Cancer Biomarkers, Infectious Agents and Cancer, Journal of Oral Pathology and Medicine, Journal of Gastric Cancer, Clinical Lymphoma, Myeloma and Leukemia, Anticancer Research, Pathology Oncology Research, Neoplasma, Clinical and Translational Oncology.

Fluorouracil (5-FU)

Fluorouracil (5-FU) is an anticancer medicine that works by slowing or stopping cell growth. The medicine interferes with the ability of abnormal cells to grow on the skin's top layer. It is used normally for Colon and rectal cancer, Breast cancer,Gastrointestinal cancers including: anal, esphageal, pancreas and gastric (stomach), Head and neck cancer. 5-FU is a Pyrimidine antagonist, belongs to the category of chemotherapy called antimetabolites. Antimetabolites are very similar to normal substances within the cell. When the cells incorporate these substances into the cellular metabolism, they are unable to divide. Antimetabolites are cell-cycle specific, Pyrimidine antagonist Serious adverse reactions to 5-FU are; chest pain, EKG changes and increases in cardiac enzymes – which may indicate problems with the heart. These symptoms are very rare but increased for patients with a prior history of heart disease.

Related journals of  Fluorouracil (5-FU)

Cancer Medicine & Anti Cancer Drugs, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Breast Cancer: Current Research, Journal of Cancer Diagnosis, Experimental and Therapeutic Medicine, Journal of Experimental Therapeutics and Oncology, Human Cell, Tumori, Translational Oncogenomics, International Journal of Cancer Research, Analytical Cellular Pathology, Cancer Treatment and Research.

Anti-Cancer Drugs

"Cancer" is the term we give to a large group of diseases that vary in type and location but have one thing in common: abnormal cells growing out of control. Under normal circumstances the number and growth of all our cells is a highly controlled mechanism. But when the control signals in one of these cells goes wrong, and its life cycle becomes disturbed, it divides and divides. It continues multiplying uncontrollably, and the result of this accumulation of abnormal cells is a mass of cells called a "cancer". The drugs used to treat cancer are Anti cancer drugs, when we hear about Anticancer drugs, most of us immediately think of chemotherapy. So there is now a whole range of different cancer drug treatments as cancer treatment options on offer to patients which are not chemotherapy and so do not act indiscriminately against rapidly dividing cells, but are instead purpose built, tailor made and ocused, targeted, with purpose ranging from hormone therapies to substances that strengthen the bones (bisphosphonates) to drugs that work with the immune system. Hormone Therapies, Steroids, The latest anti-cancer drugs are called Biologics.

Related journals of  Anti-Cancer Drugs

Cancer Medicine & Anti Cancer Drugs, Journal of Integrative Oncology, Journal of Oncology Translational Research, Oncology & Cancer Case Reports, Journal of Neuro Oncology, Journal of Carcinogenesis, Oral Oncology, American Journal of Translational Research, Hormones and Cancer, Advances in Biological Regulation, Cancer genetics, Journal of Neuro-Oncology, Experimental Hematology. Anti-Cancer Drugs, Journal of Experimental Therapeutics and Oncology.

Vinblastine

Vinblastine is used in combination with other chemotherapy drugs to treat Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (types of cancer that begin in a type of white blood cell that normally fights infection), and cancer of the testicles. It is also used to treat Langerhans cell histiocytosis (histiocytosis X; Letterer-Siwe disease; a condition in which too many of a certain type of white blood cell grows in parts of the body). It may also be used to treat breast cancer that has not improved after treatment with other medications and gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant) that has not improved after surgery or treatment with other medications. Vinblastine is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.

Related journals of  Vinblastine

Cancer Medicine & Anti Cancer Drugs, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Journal of Carcinogenesis & Mutagenesis, Journal of Brain Tumors & Neurooncology, Journal of Carcinogenesis, Oral Oncology, American Journal of Translational Research, Hormones and Cancer, Advances in Biological Regulation, Cancer genetics, Recent Patents on Anti-Cancer Drug Discovery, Cancer Immunity, Melanoma Research.

Pharmocology of Cancer Drugs

Cancer treatment is an area of medicine where the concepts of multi-modality, drug delivery, and personalized medicine are the most advanced. Therefore, Pharmacology of Anti-Cancer Drugs will also have a particular interest in the following issues: The synergy between chemotherapy and other anticancer modalities, including radio-, immuno- and gene therapy; the use of nanoscale particles or targeting moieties to improve drug bioavailability; and the identification of biomarkers derived from proteomics, and genomics or imaging technologies to predict response or resistance to drug treatment.

Related journals of  Pharmocology of Cancer Drugs

Cancer Medicine & Anti Cancer Drugs, Journal of Cancer Diagnosis, Journal of Oncology Translational Research, Oncology & Cancer Case Reports, Journal of Cancer Clinical Trials, Clinical Lymphoma, Myeloma and Leukemia, Cancer Biomarkers, Anticancer Research, Pathology Oncology Research, Neoplasma, Clinical and Translational Oncology, Anti-Cancer Drugs, Asian Pacific Journal of Cancer Prevention.

Methotrexate

Methotrexate is also used to treat certain types of cancer including cancers that begin in the tissues that form around a fertilized egg in the uterus, breast cancer, lung cancer, certain cancers of the head and neck, certain types of lymphoma, and leukemia (cancer that begins in the white blood cells). Methotrexate is in a class of medications called antimetabolites. Methotrexate treats cancer by slowing the growth of cancer cells. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming. Methotrexate may treat rheumatoid arthritis by decreasing the activity of the immune system. Methotrexate is used to treat severe psoriasis (a skin disease in which red, scaly patches form on some areas of the body) that cannot be controlled by other treatments. Methotrexate is also used along with rest, physical therapy, and sometimes other medications to treat severe active rheumatoid arthritis (RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) that cannot be controlled by certain other medications.

Related journals of  Methotrexate

 

Cancer Medicine & Anti Cancer Drugs,Journal of Leukemia, Chemotherapy, Cervical Cancer, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Oncology Research, Molecular Medicine Reports, Oncology Letters, International Journal of Biological Markers, Chinese Journal of Cancer Research, Technology in Cancer Research and Treatment, Analytical Cellular Pathology, Experimental and Therapeutic Medicine.

Antineoplastic Agents

Antineoplastic agents travel the body and destroy cancer cells. Many of the side effects associated with antineoplastic agents occur because treatment destroys the body's normal cells in addition to cancerous cells. Alkylating agents for Cancer treatment, They generally have limited but important uses, and often have significant hepatotoxicity. The antineoplastic agents are not easily classified. Historically, they are categorized as (1) alkylating agents, (2) antimetabolites, (3) natural products, (4) hormones and antagonists, and (5) miscellaneous. In recent years, however, the miscellaneous group has come to include some of the most important agents. Anticancer agents can also be classified by indication (lymphoma, leukemia, melanoma, solid tumor), mechanism of action (such as alkylating agents, antibiotics, biological response modifiers, antiandrogens, topoisomerase inhibitors or protein kinase inhibitors), chemical structure (folic acid analog, platinum coordination complex, purine or pyrimidine analog, monoclonal antibody) or as cytotoxic or nonspecific vs noncytotoxic or targeted.

Related journals of  Antineoplastic Agents

Cancer Medicine & Anti Cancer Drugs, Advances in Cancer Prevention, Chemotherapy, Cervical Cancer, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Apoptosis : an international journal on programmed cell death, Cancer Causes and Control, Stem Cell Reviews and Reports, Journal of Carcinogenesis, Oral Oncology, American Journal of Translational Research, Hormones and Cancer, Advances in Biological Regulation, Cancer genetics, Journal of Neuro-Oncology, Experimental Hematology.

Antimetabolites

Antimetabolites are drugs that interfere with one or more enzymes or their reactions that are necessary for DNA synthesis. They affect DNA synthesis by acting as a substitute to the actual metabolites that would be used in the normal metabolism (for example antifolates interfere with the use of folic acid). Many antimetabolites are used for therapeutic purposes. Sulfanilamides, for example, are antimetabolites that disrupt bacterial, but not human, metabolism and are used to eradicate bacterial infections in humans. Other examples include antagonists of purines (azathioprine, mercaptopurine, and thioguanine) and antagonists of pyrimidine (fluorouracil and floxuridine). Cytarabine, which also has antiviral properties, interferes with dihydrofolate reductase, which is necessary for the synthesis of tetrahydrofolate and subsequently for the synthesis of the folic acid needed for DNA formation. Methotrexate, used most often in the treatment of acute leukemia, breast cancer, lung cancer, and osteogenic sarcoma (osteosarcoma), has also been used in low doses for the treatment of rheumatoid arthritis.

Related journals of  Antimetabolites

Cancer Medicine & Anti Cancer Drugs, Journal of Leukemia, Chemotherapy, Cervical Cancer, Journal of Cancer Diagnosis, Oncogenesis, Critical Reviews in Oncogenesis, Cancer Letters, Cancer Microenvironment, Journal of Experimental and Clinical Cancer Research, Molecular Carcinogenesis, Prostate Cancer and Prostatic Diseases, Breast Cancer Research and Treatment.

Anti-tumor Antibiotics

These drugs are not like the antibiotics used to treat infections. They work by altering the DNA inside cancer cells to keep them from growing and multiplying. A major concern when giving these drugs is that they can permanently damage the heart if given in high doses. For this reason, lifetime dose limits are often placed on these drugs. Anthracyclines are anti-tumor antibiotics that interfere with enzymes involved in DNA replication. These drugs work in all phases of the cell cycle. They are widely used for a variety of cancers.Examples of anthracyclines include: Daunorubicin , Doxorubicin (Adriamycin®), Epirubicin, Idarubicin.

Related journals of  Anti-tumor Antibiotics

 

Cancer Medicine & Anti Cancer Drugs, Advances in Cancer Prevention, Chemotherapy, Cervical Cancer, Journal of Cancer Diagnosis, European Journal of Cancer, International Journal of Cancer, Carcinogenesis, International Journal of Radiation Oncology Biology Physics, Neoplasia, Genes Chromosomes and Cancer, Journal of Mammary Gland Biology and Neoplasia, Molecular Cancer.

Topoisomerase Inhibitors

These drugs interfere with enzymes called topoisomerases, which help separate the strands of DNA so they can be copied during the S phase. (Enzymes are proteins that cause chemical reactions in living cells.) Topoisomerase inhibitors are used to treat certain leukemias, as well as lung, ovarian, gastrointestinal, and other cancers.Topoisomerase inhibitors can be classified according to which type of enzyme they affect: Topoisomerase I inhibitors include: Topotecan, Irinotecan (CPT-11). Topoisomerase II inhibitors include: Etoposide (VP-16), Teniposide, Mitoxantrone (also acts as an anti-tumor antibiotic).

Related journals of  Topoisomerase Inhibitors

Cancer Medicine & Anti Cancer Drugs, Agri, Food & Aqua Journals, Biochemistry Journals, Business & Management Journals, Chemical Engineering Journals, Journals on Clinical Sciences, Cancer Genomics and Proteomics, Journal of Cancer Research and Clinical Oncology, Translational Oncology, Cancer Epidemiology, Clinical Lung Cancer, International Journal of Oncology, Cancer Research and Treatment, European Journal of Cancer Prevention.

Mitotic Inhibitors

A mitotic inhibitor is a drug that inhibits mitosis, or cell division. These drugs disrupt microtubules, which are structures that pull the cell apart when it divides. Mitotic inhibitors are often plant alkaloids and other compounds derived from natural products. They work by stopping mitosis in the M phase of the cell cycle but can damage cells in all phases by keeping enzymes from making proteins needed for cell reproduction. They are used to treat many different types of cancer including breast, lung, myelomas, lymphomas, and leukemias.

Related journals of  Mitotic Inhibitors

Cancer Medicine & Anti Cancer Drugs, Chemistry Journals, Journals on Clinical Sciences, Material Sciences Journals, Medical Journals, Recent Patents on Anti-Cancer Drug Discovery, Cancer Immunity, Melanoma Research, Leukemia Research, Familial Cancer, Tumor Biology, Molecular Imaging and Biology, Cancer Investigation, Cancer medicine.

Cytotoxic Drugs

Cytotoxic drugs (sometimes known as antineoplastics) describe a group of medicines that contain chemicals which are toxic to cells,. Cytotoxic drugs inhibit or prevent the function of cells. Cytotoxic drugs are primarily used to treat cancer, frequently as part of a chemotherapy regime. Recently, their uses have expanded to treat certain skin conditions (e.g., psoriasis), rheumatoid and juvenile rheumatoid arthritis, and steroid-resistant muscle conditions. The most common forms of cytotoxic drugs are known as antineoplastic. The terms ‘antineoplastic’ and ‘cytotoxic’ are often used interchangeably. Cytotoxic drugs have also been associated with negative health effects for developing fetuses, including higher incidences of spontaneous abortions, congenital malformations, low birth weight, and infertility. As part of any cytotoxic exposure reduction plan, protective reassignment for a worker who is pregnant, breastfeeding or intends to conceive a child must be put in place.

Related journals of  Cytotoxic Drugs

Cancer Medicine & Anti Cancer Drugs, Journals on Clinical Sciences, Material Sciences Journals, Medical Journals, Agri, Food & Aqua Journals, Cancer Biology and Medicine, Brain Tumor Pathology, Journal of Biological, Regulators and Homeostatic Agents, Breast Cancer: Basic and Clinical Research, Cancer Biotherapy and Radiopharmaceuticals, Oncology Research, Molecular Medicine Reports, Oncology Letters.

Hormonal Drugs for Cancer Therapy

Hormone therapy is a form of systemic therapy that works to add, block or remove hormones from the body to slow or stop the growth of cancer cells. Hormone therapies slow or stop the growth of hormone receptor-positive tumors by preventing the cancer cells from getting the hormones they need to grow. They do this in a few ways. Some hormone therapies, like the drug tamoxifen, attach to the receptor in the cancer cell and block estrogen from attaching to the receptor. Other therapies, like aromatase inhibitors, lower the level of estrogen in the body so the cancer cells cannot get the estrogen they need to grow. Hormone therapy for breast cancer treatment is different from menopausal hormone therapy (MHT). MHT may also be called postmenopausal hormone use or hormone replacement therapy.

Related journals of  Hormonal Drugs for Cancer Therapy

Cancer Medicine & Anti Cancer Drugs,Journal of Leukemia, Chemotherapy, Journal of Cancer Science & Therapy, Journal of Cancer Clinical Trials, Endocrine-Related Cancer, Clinical and Experimental Metastasis, Cancer Journal, Angiogenesis, Cancer Immunology and Immunotherapy, Cancer Science, Lung Cancer, Epigenomics, Journal of Hematology and Oncology, Journal of Immunotherapy, Current Opinion in Oncology, BMC Cancer.

Chemotherupatic Agents

Chemotherapy is a form of cancer treatment that involves taking one or more of a type of drug that interferes with the DNA (genes) of fast-growing cells. These drugs are further subdivided into specific classes such as alkylating agents, antimetabolites, anthracyclines, and topoisomerase inhibitors. They are usually given by IV infusion (slowly injected into your vein), but can be given orally (in pill form) or by direct infusion into a limb or the liver. Chemotherapy drugs used to treat melanoma include dacarbazine, temozolomide, paclitaxel, cisplatin, carmustine, fotemustine, vindesine, vincristine, and bleomycin. Combinations of chemotherapy agents are also often for melanoma -- the CVD (cisplatin, vincristine and dacarbazine) and BVLD (bleomycin, vincristine, lomustine and dacarbazine).

Related journals of  Chemotherupatic Agents

Cancer Medicine & Anti Cancer Drugs, Journal of Cancer Diagnosis, Journal of Cancer Clinical Trials, Journal of Carcinogenesis & Mutagenesis, Chemotherapy, Cancer Biology and Therapy, Cancer Chemotherapy and Pharmacology, Current Medicinal Chemistry - Anti-Cancer Agents, Cancer Biotherapy and Radiopharmaceuticals, Recent Results in Cancer Research, Current Medicinal Chemistry - Anti-Cancer Agents, Oncology Reports, American Journal of Clinical Oncology, Molecular Cancer Therapeutics.

Carcinogens

A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Carcinogens are agents that can cause cancer. In industry, there are many potential exposures to carcinogens. Generally, workplace exposures are considered to be at higher levels than for public exposures. Material safety data sheets (MSDSs) should always contain an indication of carcinogenic potential.

Related journals of  Carcinogens

Cancer Medicine & Anti Cancer Drugs, Journal of Leukemia, Journal of Carcinogenesis & Mutagenesis, Chemotherapy, Journal of Brain Tumors & Neurooncology, Cancer, Molecular Oncology, Genes and Cancer, Epigenetics, Advances in Cancer Research, Oncologist, Molecular Cancer Research, Gastric Cancer, British Journal of Cancer.

Purine Antagoinsts for Cancer Treatment

The purine antagonists function by inhibiting DNA synthesis in two different ways They can inhibit the production of the purine containing nucleotides, adenine and guanine. If a cell doesn't have sufficient amounts of purines, DNA synthesis is halted and the cell cannot divide.They may be incorporated into the DNA molecule during DNA synthesis. The presence of the inhibitor is thought to interfere with further cell division.

Related journals of  Purine Antagoinsts for Cancer

Cancer Medicine & Anti Cancer Drugs, Journal of Integrative Oncology, Journal of Oncology Translational Research, Oncology & Cancer Case Reports, Journal of Neuro Oncology, Treatment Cancer Prevention Research, Cell death & disease, Seminars in Radiation Oncology, Frontiers in Oncology, Targeted Oncology, Current Cancer Drug Targets, Cellular Oncology.

Chemo Side Effects

It's difficult to predict exactly what side effects you'll experience while having chemotherapy. Different people react to treatment in different ways. Many of the common side effects of chemotherapy are listed below, Hair loss is a potential side effect of chemotherapy. Anemia, Appetite Loss, Bleeding and Bruising (Thrombocytopenia),Constipation, Diarrhea, Edema, Fatigue, Hair Loss (Alopecia), Infection and Neutropenia, Lymphedema, Memory or Concentration Problems, Mouth and Throat Problems, Nausea and Vomiting, Nerve Problems (Peripheral Neuropathy), Pain, Sexual and Fertility Problems (Men), Sexual and Fertility Problems (Women), Skin and Nail Changes, Sleep Problems, Urinary and Bladder Problems.

Related journals of  Chemo Side Effects

 Cancer Medicine & Anti Cancer Drugs, OMICS Journal of Radiology,  Material Sciences Journals, Medical Journals, Journal of Cancer Diagnosis, American Journal of Clinical Oncology, Cancer Informatics, Nuclear Medicine and Biology, Nutrition and Cancer, Cancer Gene Therapy, Cancers, Japanese Journal of Clinical Oncology, Environmental Carcinogenesis and Ecotoxicology Reviews.


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