Clinical Course Of Multiple Sclerosis

Results of key natural history of studies from carefully managed data sets have unfortunately lead some leading experts in the field of multiple sclerosis to conclude that the most severe cases of multiple sclerosis are causally connected to degenerative processes as the primary driver of disability. For research purposes more precise language and definitions can and should be developed, but in practice neurologists already are thinking in terms of inducing remission. It is a testament to the apparent efficacy of our new and old armamentarium of therapeutic agents for multiple sclerosis that we have now begun to think this way. “MS in apparent therapy induced remission”: If a patient with at least moderate disability accumulation stabilizes within 6 months of a new treatment and maintains stabilization for a year or more, we are certainly tempted to conclude that our change in therapy has induced a remission.

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Last date updated on April, 2024