ISSN: 2332-0737

Current Synthetic and Systems Biology
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Editorial Board

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Yue Zhang
University Health Network

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Yeoheung Yun
North Carolina Agricultural & Technical State University

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Barry Wanner
Purdue University

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Journal Impact Factor 1.3*
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About the Journal

Current Synthetic and Systems Biology is an academic journal that provides an opportunity to researchers and scientist to explore the advanced and latest research developments in the field of synthetic and system biology and related academic disciplines.

Current Synthetic & Systems Biology engages its audience by publishing wide range of topics on the emerging field of synthetic and system biology such as the design and construction of biological devices and systems for a variety of biotechnology and medical applications, combining biological research and engineering,

designing, modifying and constructing synthetic gene networks with network systems biology approaches to fight infectious diseases diabetes. Current Synthetic and Systems Biology is a scholarly open access journal and aims to publish the most complete and reliable source of information on the advanced and very latest research topics.

Current Synthetic and Systems Biology is a peer reviewed scientific journal known for rapid dissemination of high-quality research. This Current Synthetic and Systems Biology Journal with high impact factor offer an open access platform to the authors in academia and industry to publish their novel research. It serves the International Scientific Community with its standard research publications.

This journal is using Editorial Manager System for quality in review process. Editorial Manager is an online manuscript submission, review and tracking systems. Editorial board members of Current Synthetic and Systems Biology journal or outside experts review the manuscripts; at least two independent reviewer’s approval followed by the editor is required for the acceptance of any citable manuscript.

Submit manuscript at or send as an e-mail attachment to the Editorial Office at or

Synthetic Genomics

Synthetic genomics is useful for the synthesis of DNA. It gives the methods which are the combination of chemical and computational techniques. By this combination of methods the work which is almost impossible by using conventional techniques became easier. It is possible to design and assemble the whole genome by using synthetic genomics.

Synthetic genomics combines methods for the chemical synthesis of DNA with computational techniques to design it. These methods allow scientists to construct genetic material that would be impossible or impractical to produce using more conventional biotechnological approaches. Potential possible applications are biological production of fuels, vaccines generation against emerging microbial disease.

Related Journals of Synthetic Genomics
Current Synthetic and Systems Biology, Journal of Molecular Pharmaceutics & Organic Process Research, Journal of Proteomics & Bioinformatics, Journal of Molecular and Genetic Medicine, Journal of Clinical & Medical GenomicsAnnual Review of Genomics and Human Genetics, Applied and Translational Genomics. BMC Genomics, BMC Medical Genomics, Cancer Genomics and Proteomics. Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics

Functional Genomics

Functional genomics focuses mainly on the active aspects such as transcription, translation and protein interactions etc. It helps us to get the answers about the function of DNA at the levels of genes, RNA transcripts and protein products. It is also to expand genomic and proteomic knowledge into an understanding of dynamic properties of an organism. Functional genomics mainly includes function related aspects of a genome such a mutations and polymorphism.

Functional genomics uses genomic data to study about gene and protein expression and its function on a global scale (genome-wide or system-wide). it focuses on gene transcription, translation and protein-protein interactions, and often involving high-throughput methods. The study of expressed genes in organisms, including the identity of the genes and the factors that control differential expression. 

Related Journals of Functional Genomics
Current Synthetic and Systems BiologyJournal of Drug Metabolism & ToxicologyJournal of Data Mining in Genomics & ProteomicsJournal of Pharmacogenomics & PharmacoproteomicsMolecular Biology, Current Genomics, Current Pharmacogenomics and Personalized Medicine, Epigenomics, Functional and Integrative Genomics, Genes and Genomics, Genome Mapping and Genomics in Animals

Animal and Tissue Engineering

Animal engineering is to produce animals by the modification of genes to get our desired traits by using recombinant DNA technology. This is mainly to farm animals which grow faster, have healthier meat and flesh. Tissue engineering is to understand the principles of tissue growth and apply this to functional replacement of a tissue for clinical use. This will allow organs to be grown by implantation.

This is the science that deals with altering and cloning genes to produce a new trait in an organism or to make a biological substance, such as a protein or hormone. Genetic engineering mainly involves the creation of recombinant DNA, which is then inserted into the genetic material of a cell or virus of an animal.

Related Journals of Animal and Tissue Engineering
Current Synthetic and Systems Biology, Journal of Biomimetics Biomaterials and Tissue Engineering, Journal of Stem Cell Research & Therapy, Autism-Open Access, Biochemistry & Analytical Biochemistry, Journal of Biomimetics, Biomaterials, and Tissue Engineering, Journal of Clinical Rehabilitative Tissue Engineering Research, Open Tissue Engineering and Regenerative Medicine Journal, Tissue Engineering - Part A, Tissue Engineering - Part A, Tissue Engineering and Regenerative Medicine


Bioinformatics is the field that develops the methods and software tools for understanding biological data. Bioinformatics obtains the knowledge from computer analysis of biological data. it consist of the information stored in the genetic code, but also experimental results from various sources, patient statistics, and scientific literature. The techniques like image and signal processing allow extraction of results from large amount of raw data. Bioinformatics tools helps to compare genetic and genomic data. It also plays a role in the analysis of gene regulation and protein expression.

Research in bioinformatics includes method development for storage, retrieval, and analysis of the data. Bioinformatics is a rapidly developing branch of biology and is highly interdisciplinary, using techniques and concepts from informatics, statistics, mathematics, chemistry, biochemistry, physics, and linguistics.Common activities of bioinformatics include mapping and analyzing DNA and also to create 3D structures of a protein. It has many practical applications in different areas of biology and medicine

Related Journals of Bioinformatics
Current Synthetic and Systems Biology, Journal of Phylogenetics & Evolutionary Biology, Journal of Advanced Chemical Engineering, Journal of Microbial & Biochemical Technology, Journal of Data Mining in Genomics & Proteomics,  Advances and Applications in Bioinformatics and Chemistry, Advances in Bioinformatics, Bioinformatics, Bioinformatics and Biology Insights, BMC Bioinformatics, Briefings in Bioinformatics, Current Bioinformatics

Industrial Biotechnology

Industrial biotechnology utilizes enzymes and microorganisms to produced bio-based products in the industries such as chemical, detergents, paper and pulp. Is uses renewable materials for the production of new useful products. These innovative approaches lower the green house gas emissions.biotechnology is the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials and organisms such as pharmaceuticals, crops, and livestock.

White biotechnology yields more and more viable solutions for our environment. It also helps to improve the industrial performance and product value.

Related Journals of Industrial Biotechnology
Journal of Biotechnology & Biomaterials, Journal of Bioprocessing & Biotechniques, Journal of Phylogenetics & Evolutionary Biology, Chemical Sciences Journal, Journal of Advanced Chemical Engineering, Industrial Biotechnology, Animal Biotechnology, African Journal of Biotechnology, African Journal of Biotechnology, Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology, Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology

P4 medicine

P4 medicine is the clinical face of systems medicine. It will make blood a diagnostic window for viewing health and disease for the individual. It provides new approaches to discover the drug target. These medicines will necessitate a fundamental change in the business of every sector of health care industry over the next ten years. This will provide challenges to existing companies and opportunities to create new companies.

P4 medicine promises to sharply reverse the ever escalating costs of healthcare – introducing diagnosis to stratify patients and disease, less expensive approaches to drug discovery, preventive medicine and wellness, and exponentially cost‐decreasing measurement technologies. P4 medicine also promises to improve patient outcomes, and to empower both the patient and the physician.

Related Journals of P4 medicine
Journal of Health & Medical Informatics, Medical & Surgical Urology, Translational Medicine, Tropical Medicine & Surgery , Biology and Medicine, Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], Yale Journal of Biology and Medicine, Yale Journal of Biology and Medicine, WSEAS Transactions on Biology and Biomedicine, Wound Medicine

Synthetic Biology medicine

Synthetic medicine is the use of engineered biomolecular system having endless applications. The synthetic biology has surprised the scientific community with is progress over a decade.Synthetic biology is a maturing scientific discipline that combines science and engineering in order to design and build novel biological functions and systems. This includes the design and construction of new biological parts, devices, and systems, as well as the re-design of existing, natural biological systems for useful purposes.

Some of the applications include cancer treatment, vaccine development, microbiome engineering, cell therapy and regenerative medicine. It also uses artificial engineered viruses to treat bacterial infections.

Related Journals of Synthetic Biology medicine
Medical & Surgical Urology, Journal of Sports Medicine & Doping Studies, Journal of Forensic Research, Journal of Computer Science & Systems Biology, Medicinal Chemistry, ACS Synthetic Biology, Systems and Synthetic Biology, Advances in Experimental Medicine and Biology, American Journal of Tropical Medicine and Hygiene, Anil Aggrawal's Internet Journal of Forensic Medicine and Toxicology, Annals of Laboratory Medicine

Ethics in Synthetic Biology

The synthetic biology is a very advanced form of engineering organisms which focus on creating autonomous biological pathways to rewrite the cellular function which may in turn pollute the genetic variation among the species. We may also not know the adverse effects of integrating synthetic compounds into biological systems. Bringing up human health applications with this new technology needed government certification, ethical clearance and enormous care is to be taken with constant monitoring during clinical trials.

Related Journals of Ethics in Synthetic Biology

Current Synthetic and Systems Biology, Journal of Carcinogenesis & Mutagenesis, Translational Medicine, Journal of Glycomics & Lipidomics, Anatomy & Physiology: Current Research, ACS Synthetic Biology, Journal of Synthetic Biology, Systems and Synthetic Biology, International Journal of Systems and Synthetic Biology, synthetic biology-Journal of The Royal Society Interface, Synthetic systems biology

Chemistry of Biology

Chemical biology is a stream which deals with the application of chemistry and physics in biology. Some of the synthetically manufactured compounds are engineered to manipulate biological molecules. Biomolecules such as lipids, nucleic acids, carbohydrates and proteins are studied for their chemical and physical properties to know their state and function.

Modern biology overlaps with chemistry in explaining the structure and function of all cellular processes at the molecular level.

Related Journals of Chemistry of Biology
Medicinal Chemistry, Organic Chemistry: Current Research, Biochemistry & Pharmacology: Open Access, Molecular Biology, Natural Products Chemistry & Research, Chemistry & Biology - Journal - Elsevier, ACS Chemical Biology (ACS Publications), Journal of Chemical Biology, Nature Chemical Biology, The Journal of Biological Chemistry, Chemical Biology & Drug Design - Wiley Online Library

Biology Engineering

Bioengineering is the manipulation of the biological compounds varying their physical and chemical forms using engineering principles and techniques. Engineering is done at cellular and subcellular level i.e. molecular level.Bioengineering is the “biological or medical application of engineering principles or engineering equipment. Bioengineering defined as a field is relatively new, although attempts to solve biological problems have persisted throughout history. 

Recently, the practice of bioengineering has expanded beyond large-scale efforts like prosthetics and hospital equipment to include engineering at the molecular and cellular level – with applications in energy and the environment as well as healthcare.
They have wide range of biological and environmental application like biosensors, food safety, diagnosis, cell free protein production, biofuels etc.

Related Journals of Biology Engineering
Journal of Biotechnology & Biomaterials, Journal of Tissue Science & Engineering, Journal of Bioprocessing & Biotechniques, Journal of Cytology & Histology, Single Cell BiologyJournal of Biological Engineering, Journal of Medical and Biological Engineering, Bioengineering Biomedical Journals, International Journal of Biomedical Engineering and Technology, Journal of Bio Engineering, Biomedical Engineering and Computational Biology

Synthetic biology drugs

Synthetic biology uses the organisms to manufacture the targeted drugs by recombining artificial biosynthetic pathways in the host. Some the of the drugs produced by this application are vancomycine, cyclosporine. Synthetic biology is the engineering of biology: the synthesis of complex, biologically based (or inspired) systems which display functions that do not exist in nature.

This engineering perspective may be applied at all levels of the hierarchy of biological structures – from individual molecules to whole cells, tissues and organisms. In essence, synthetic biology will enable the design of ‘biological systems’ in a rational and systematic way.
Synthetic biologists use polypeptides for the manufacturing of desired drugs assembling all together into a single complex

Related Jornals of Synthetic Biology Drugs
Current Synthetic and Systems Biology, Journal of Developing Drugs, Journal of Cytology & Histology, Medicinal Chemistry, Natural Products Chemistry & Research, BioDrugs, Cardiovascular Drugs and Therapy, Chinese Journal of New Drugs, Drugs in Context, Drugs in R and D, Drugs of the Future, International Journal for Parasitology-Drugs and Drug Resistance, Journal of Psychoactive Drugs

Synthetic Biology

Synthetic biology is engineering and manipulating biomolecular systems and cellular capabilities. This involves the construction of the biological systems from the minute functional unit to the functional cellular level. Synthetic biology is the engineering of biology: the synthesis of complex, biologically based (or inspired) systems which display functions that do not exist in nature. This engineering perspective may be applied at all levels of the hierarchy of biological structures – from individual molecules to whole cells, tissues and organisms. In essence, synthetic biology will enable the design of ‘biological systems’ in a rational and systematic way. 

Synthetic biology is of two types which one using unnatural molecules to reproduce natural behavior and the other interchanges the parts from one system to another to ultimately assembled resulting in a unnatural function.

Related Journals of Synthetic Biology
Journal of Molecular Pharmaceutics & Organic Process Research, Journal of Developing Drugs, Journal of Cytology & Histology, Medicinal Chemistry, Natural Products Chemistry & Research, ACS Synthetic Biology, Journal of Synthetic Biology, Systems and Synthetic Biology - incl, International Journal of Systems and Synthetic Biology, synthetic biology-Journal of The Royal Society Interface

Synthetic Biotechnology

Synthetic biotechnology involves the manipulation of biological compounds like integration of synthetic aminoacids into proteins, DNA synthesis and manipulation using synthetic sequences, oligonucleotide synthesis, protein modification using synthetic compounds etc. the compounds produced synthetically are orthogonally integrated into cells which are chosen to provide suitable experimental strategy.

Synthetic biology represents a convergence of advances in chemistry, biology, computer science, and engineering. systematic methods for increasing the speed, scale, and precision with which we engineer biological systems. In a sense, synthetic biology can be thought of as the development of a biology-based “toolkit” that enables improved products across many industries, including medicine, energy and the environment.The manipulations in the wild type system by the engineered systems are studied varying their efficiency

Related Journals of Synthetic Biotechnology
Journal of Biotechnology & Biomaterials, Journal of Advanced Chemical Engineering, Journal of Bioprocessing & Biotechnique, Chemical Sciences Journal, Biology and MedicineArtificial Cells, Nanomedicine and Biotechnology, Advances in Biochemical Engineering/Biotechnology, African Journal of Biotechnology, American Journal of Biochemistry and Biotechnology, Animal Biotechnology, Asian Biotechnology and Development Review, Australasian Biotechnology

Gene Synthesis

Genes are a stretch of nucleotides which codes for a single polypeptide sequence. Genes are isolated and amplified artificially by PCR with gene specific primers if the sequence is known and sequenced. The desired sequence is synthesized artificially by solid phase DNA synthesis. Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences.

It is possible to make synthetic double stranded DNA molecule with no size limits. Oligonucleotides are synthesized by phosphoramidite nucleosides artificially. The used nucleosides can be natural or artificial. In 2010 mycoplasma genome was successfully synthesized artificially

Related Journals of Gene Synthesis
Journal of Thermodynamics & Catalysis, Human Genetics & Embryology, Journal of Clinical Research & Bioethics, Clinical & Experimental Pharmacology, Gene TechnologyAdvances in Genetics, American Journal of Human Genetics, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Biochemical Genetics, Behavior Genetics, Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Advanced DNA Sequencing

DNA sequencing is the process of determining the precise order of the nucleotides in DNA. Genome sequencing helps us to understand the genetic biology and has vast potential for medical diagnosis and treatment.DNA sequencing technologies have gone through at least three "generations": Sanger sequencing and Gilbert sequencing were first-generation, pyrosequencing was second-generation, and Illumina sequencing is next-generation.

Advanced methods of sequencing involve shotgun sequencing, denovo sequencing. De novo sequencing is used to determine the sequence of the desired DNA with no known sequence. Shortgun method is designed to analyse the sequences longer than 1000 bp where the large genome in broken down into random fragments. Both the techniques are used to sequence entire chromosomes.

Related Journals of Advanced DNA Sequencing
Journal of Next Generation Sequencing & Applications, Cloning & Transgenesis, Advancements in Genetic Engineering, Journal of Molecular Biomarkers & Diagnosis, Journal of Probiotics & Health, Next Generation Sequencing - Oxford Journals, Genomics - Journal - Elsevier, Artificial DNA: PNA and XNA, DNA and Cell Biology, DNA Repair, Recent Patents on DNA and Gene Sequences, Privredna Kretanja i Ekonomska Politika

Current Synthetic and Systems Biology is associated with our international conference " International Conference on Synthetic Biology " during September 28-30, 2015 Houston, USA with a theme " Recent Advancement and Discoveries in Synthetic". We are particularly interested in increased genome sequencing efforts have ushered in a new era of systems biology, in which entire cellular networks are analyzed and optimized for application in the development of strains and Bioprocesses.

*Unofficial 2015 Journal Impact Factor was established by dividing the number of articles published in 2013 and 2014 with the number of times they are cited in 2015 based on Google search and the Scholar Citation Index database. If 'X' is the total number of articles published in 2013 and 2014, and 'Y' is the number of times these articles were cited in indexed journals during 2015 then, impact factor = Y/X

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