ISSN: 2161-0495

Journal of Clinical Toxicology
Open Access

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Editorial Board

Ken Ichiro Inoue

Editor-in-Chief
Ken Ichiro Inoue
Professor
University of Shizuoka
Japan

Biography :

Dr.Ken-ichiro Inoue is currently, working as Professor in Center for Medical Science, International University of Health and Welfare, Japan. He has successfully completed his Administrative responsibilities as Professor of Department of Public Health and Molecular Toxicology, School of Pharmacy, Kitasato University, Japan. He has authored 121 research articles.

 Biography
Research Interest :

Environmental Immunotoxicology.
Chemical and Atmospheric Research in Toxicology.

 Research Interest
 Network
 Acceptance Letter
Noreen Khan Mayberry

Editor-in-Chief
Noreen Khan Mayberry
Science and Aeronautics Research Directorate
NASA
USA

Biography :

Dr. Noreen Khan-Mayberry received her PhD in EnvironmentalToxicology from Texas Southern University in 2003.  Currently, she is detailed to the NASA as a Scientific Technical Expert and has served a Space Toxicologist at NASA since 2004. She has successfully completed her Administrative responsibilities as a Space Toxicologist, US Chair of the International Air Quality Working Group, Project Manager of the Advanced Environmental Health project and Technical Manager of the Lunar Airborne Dust Toxicology Assessment Group.
She is currently serving as an editorial member of the The International Journal of Disaster Advances. She has authored a number of research articles in space Toxicology and planetary dust toxicity and served as the lead author of the first chapter featuring the specialty of Space Toxicology ever to be featured in an International Toxicology textbook. She is a Fellow of the International Congress of Disaster Management and a member of the Society of Toxicology and the American College of Toxicology. She has been honoredas a 2010 Technology Rising Star and a distinguished guest speaker at the Women as Global Leaders international conference, among several other awards.

 Biography
Research Interest :

Toxicology – Air Quality, Respiratory Toxicology, Environmental Toxicology, Food Toxicology, Aerotoxic Syndrome, Nutrigenomics, Biology – Microbial research (mycotoxins).

 Research Interest
 Network
Rajat Sethi

Rajat Sethi
Assistant Dean
Texas A&M Health Science Center
USA

Biography :

Rajat Sethi completed his Ph.D in Physiology from University of Manitoba, Canada and is currently the Assistant Dean for Research and Evidence based Practice at the Texas A&M Health Science Center- College of Nursing. He has published more than 30 peer reviewed papers in cardiac pathology, holds 15 patents, has authored 5 books and serves in the editorial board for many journals.

 Biography
Research Interest :
 Research Interest
 Network
Asok Dasmahapatra

Asok Dasmahapatra
School of Pharmacy
University of Mississippi
USA
Tel. 662 915 7077
Fax 662 915 5148

Biography :

Dr. Asok Dasmahapatra is an Assistant Professor of Pharmacology in the Department of Pharmacology and Research Scientist at the National Center for Natural Product Research at the School of Pharmacy of the University of Mississippi University, Oxford Mississippi, USA. He holds a BSc Honours MSc degrees in Zoology from the University of Burdwan West Bengal, India and Ph D Degree in Zoology from the University of Calcutta, West Bengal, India.He had postdoctoral training at the Department of Chemistry, Florida State University, Tallahassee, Florida, USA, Department of Gastroenterology Medical College of Wiscons in Milwaukee, Wisconsin and in the Department of Biological Sciences University of Wiscons in Milwaukee. He worked as a Research Specialist at the Center for Great Lakes studies at the University of Wiscons in Milwaukee, USA.

 Biography
Research Interest :

Dr Dasmahapatra’s research interests are mainly focused on Toxicology, Endocrinology and Molecular Biology. He is currently concentrated on Developmental Toxicology focusing on Fetal alcohol syndrome (FAS) and looking for the genes responsible for these developmental disorders. He is now mentoring graduate students who are searching a natural product that can prevent FAS.

 Research Interest
 Network
 Acceptance Letter
David R Wallace

David R Wallace
Professor
Department of Pharmacology and Physiology
Oklahoma State University Center for Health Sciences
USA
Tel. 918 230 8524
Fax 918 561 5729

Biography :

Dr. Wallace received his Bachelor of Science degree from Western Michigan University in 1983 in Biomedical Sciences. His graduate work was completed at the University of Florida where he received his Doctoral degree in 1991 in Pharmaceutical Sciences. His first postdoctoral fellowship was at the University of Colorado (1990-92). Dr. Wallace joined the Oklahoma State University in 1996 after a 4 year fellowship at the University of Kentucky. Since his arrival, Dr. Wallace has been actively involved in teaching 2nd year medical students as well as graduate students in the Biomedical Science Program and the Forensic Science Program. Dr. Wallace has been extensively trained in basic pharmacological, neurochemical and neurotoxicological methods such as radioligand binding, neurotransmitter uptake/release and intracellular assays. The major foci and interests of the Wallace Laboratory are the mechanisms underlying neurotoxicity in the Central Nervous System (CNS) with a primary focus on environmental toxin and their effects on the dopaminergic neurotransmitter system.

 Biography
Research Interest :

My laboratory has 3 major projects currently underway. Project 1 examines the interaction between gp120/Tat (HIV proteins associated with neurotoxicity), estrogen, and cocaine in female rats. Ultimately, the goal of this research is to provide insight into gender-related differences in AIDS-related central nervous system disorders leading to potential gender-specific treatment strategies for HIV and cocaine addiction.  Project 2 examines the effects of low-level heavy metal exposure on the dopaminergic function in cell culture and whole animal. These studies have implications in forensic analysis and determining the potential cause of CNS damage.  Of major concern is that low-level exposure may also lead to the development of particular diseases of the CNS such as Autism Spectrum Disorders (ASD).  Project 3 investigates the use of naturally occurring compounds as centrally acting agents. One series of studies has been examining the effects of Native American plants indigenous to Oklahoma and their potential analgesic effects. A second series is investigating the estrogenic effects of flavonoids found in soy and flaxseed.

 Research Interest
 Network
 Acceptance Letter
Pierre Brochu

Executive Editor
Pierre Brochu

Professor
Departement of Environmental and Occupational Health
University of Montreal
Canada
Tel. 514 343 6111

Biography :

Dr Pierre Brochu (B.Sc., M.Sc., Ph.D.) worked for more than 30 years in environmental and human toxicology for the Quebec Government. He notably conducted studies in individuals at risk to be more affected by xenobiotics during same exposure conditions (for instance, depending upon the pollutant chosen: in children, pregnant or lactating females, or obese subjects). Exposure factors in children aged 2 to 5 years and their multimedia exposure to lead were notably part of his topics of interest. Since 2011, he is teaching and performing toxicological research at the Faculty of Medicine of the University of Montreal. He is teaching occupational diseases, health risk assessment, pulmonary toxicity, hematotoxicity, immunotoxicity, hepatotoxicity, nephrotoxicity, neurotoxicity, chemical carcinogenesis as well as reproductive and developmental toxicities. He is the first scientist to have determined alveolar ventilation rates and cardiac outputs in unrestrained free-living subjects during real-life situations and normal surroundings, over 7 to 21 days.

 Biography
Research Interest :

Current research interests of Dr Pierre Brochu notably include the determination of respiratory and cardiovascular parameters in free-living children, adults and the elderly and health risk assessment in workers, as well as individuals of the population exposed to xenobiotics. The determination of respiratory and cardiovascular data is based on spectrometric measurements of disappearance rates of oral doses of water isotopes (i.e. deuterium, 2H and heavy-oxygen ,18O) in body fluid samples (blood, urine or saliva) of free-living subjects over a long period of time – from 7 to 21 days.

 Research Interest
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Aditya Bhushan Pant

Executive Editor
Aditya Bhushan Pant

Sr. Scientist
In Vitro Toxicology
Indian Institute of Toxicology Research,
Lucknow, India
Tel. 0522- 2627586
Fax 0522-2628227

Biography :

Dr. Pant started his research career about twenty four years back at Central Drug Research Institute, Lucknow, and established in vitro models to obtain the high amount of malaria parasite antigens for vaccine purposes. He earned his PhD degree in ‘Biotechnology’, from IIT Roorkee, India. In 1997, he joined Indian Institute of Toxicology Research, Lucknow, and established State of the Art Laboratory for In Vitro Toxicology. Currently, he is developing rapid and sensitive in vitro model of study the chemical and drug induced developmental neurotoxicity using growth factors induced differentiating neuronal sub-types derived from human umbilical cord blood stem cells. Dr. Pant has more than hundred research publication in national and international journals of high repute and has many other quantifiable achievements in his credit. He has guided more than 11 PhD, over 120 MSc/MTech, 22 MDS/MD, 16 BTech, and 5 Post Doctoral Fellow and many students are currently working under him in different projects. Dr. Pant is fellow of number of scientific societies/academies, to name few: Academy of Toxicological Sciences (USA), Society of Toxicology (India), Academy of Sciences for Animal Welfare (India), Academy of Environmental Biology (India), etc.

 Biography
Research Interest :

In vitro toxicology.
Developmental toxicology.
Pesticides.

 Research Interest
 Network
Zia Shariat Madar

Executive Editor
Zia Shariat Madar
Department of Pharmacology
School of Pharmacy
University of Mississippi
USA
Tel. 662 915 5150

Biography :

Zia Shariat Madar, PhD is in the School of Pharmacy at the University of Mississippi. He received his BS degree in Biology and MS degree in Public Health Education from Central Michigan University. He received his Ph.D in Pharmacology at the Medical University of Ohio and did postdoctoral work at the University of Michigan.

 Biography
Research Interest :

His research interests include normal and pathological hypertrophy and inflammation in brain microvessels.

 Research Interest
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 Acceptance Letter
Michael Aschner

Michael Aschner
Professor
Vanderbilt University
USA
Read Interview session with Michael Aschner

Biography :

Michael Aschner is the Gray E B Stahlman Professor of Neuroscience in the Department of Pediatrics at the Vanderbilt University Medical Center. His research interests are in the Neurobiology and Physiology of astrocytes and the mechanisms of CNS injury Current studies address gene environment interactions in mercury and manganese induced neurotoxicity and carried out in C elegans and rats. The impact of manganese on neurodevelopment is assessed in human neonates by means of MRI. Dr. Aschner has served on numerous national and international toxicology panels Institute of Medicine EPA CDC served and chaired the ALTX3 NIH study section. He has authored 8764; 350 peer reviewed manuscripts and chapters and serves as an Associate Editor for Neurotoxicology and Toxicological Sciences. He has been a member of the Society of Toxicology SOT and the Academy of Toxicological Sciences. He held the presidency of the International Neurotoxicology Association. He is also the recipient of the 2010 SOT Merit Award.

 Biography
Research Interest :

Cellular & Molecular mechanisms of heavy metal neurotoxicity,Gulf War syndrome, Neurodegeneration,Neuron-glia interaction.

 Research Interest
 Network
Richard L Doty

Richard L Doty
Professor and Director
University of Pennsylvania School of Medicine
USA
Tel. 215 662 6580
Fax 215 349 5266

Biography :

Richard L. Doty is the Director of the Smell and Taste Center and Professor in the Department of  Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia.  The author or co author of more than 350 professional publications, as well as 9 books, he serves as an editorial consultant to over 50 scientific journals.  He is the recipient of many prestigious awards, including the James A. Shannon Award from the National Institutes of Health (1996), the Scientific Sense of Smell Award from the Olfactory Research Fund (2000), the William Osler Patient-Oriented Research Award from the University of Pennsylvania (2003), the Service Award from the Society of Cosmetic Chemists (2004), and the Association for Chemoreception Science’s Max Mozell Award for Outstanding Achievement in the Chemical Senses (2005).  He was elected to fellow of the American Association for the Advancement of Science in 2005.  Dr. Doty received the B.S. degree in psychology from Colorado State University (1966), the M.A. degree from California State University, San Jose, in conjunction with the National Aeronautics and Soace Administration, Moffett Field, CA (1968), and the Ph.D. degree from Michigan State University, East Lansing (1971).  He received post-doctoral fellowship training at the University of California, Berkeley (1971-1973), and at the University of Pennsylvania, Philadelphia (1973-1975).

 Biography
Research Interest :

Richard L Doty Research Interests are Aging; olfaction; taste; behavioral pharmacology; neurodegenerative diseases & schizophrenia; chemosensory psychophysics; psychopharmacology; multiple sclerosis; functional magnetic resonance imaging.

 Research Interest
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Shayne Gad

Shayne Gad
Principal
Gad Consulting Services
USA
Tel. 919-233-2926
Fax 919-233-2927

Biography :

Over 35 years experience as a toxicologist, statistical consultant, manager and consultant on research and development in the chemical, consumer product, contract testing, biotechnology, medical device, and pharmaceutical industries. Experienced in occupational and industrial toxicology, development programs (both preclinical and clinical) and study design, conduct and reporting, in evaluating clinical and product safety data, in training and managing staff; in dealing with a wide range of U.S. and foreign regulatory bodies, commercial concerns, and contract research organizations; in labeling and other FDA compliance issues for drugs, devices and dietary supplements; identifying, developing and putting into everyday use new technology; in writing reports, position papers, Material Safety Data Sheets, MAA/PLA/IND/NDA/PNA toxicology and pharmacokinetic summaries and package inserts; in preparing and maintaining INDs, MMFs, NADAs , DMFs, IDEs and 510(k)s; in preparing labels and package inserts for drugs, devices, combination products and consumer products; in presentations to FDA and in designing experiments, designing and executing surveys; in the pharmacokinetic and statistical analysis of both experimental and clinical data; in risk assessment; in Proposition 65 assessments and labeling; in the registration of OTC, dietary supplement, nutraceutical, and sterilant products with FDA; and in the development and production of biologic products.

 Biography
Research Interest :

Neuro, immune and cardiovascular toxicolgy.
Drug and device safety.

 Research Interest
 Network
Warren G Foster

Warren G Foster
Professor
Department of Obstetrics & Gynecology
McMaster University
Canada

Biography :

Dr. Foster is a Professor in the Department of Obstetrics & Gynecology at McMaster University and an Adjunct Professor in the Department of Cellular Biology and Pharmacology at Florida International University. Professor Foster is an expert in reproductive biology and toxicology. His studies address human exposure to environmental contaminants including endocrine disrupters. Ongoing studies in his laboratory explore the cellular and molecular mechanisms underlying adverse reproductive health outcomes including dysregulation of ovarian function and endometriosis. He is an editor for the Journal of Applied Toxicology and past President of the Canadian Fertility and Andrology Society. His research is supported by finding from the Canadian Institutes of Health Research (CIHR), Health Canada, and the pharmaceutical industry.

 Biography
Research Interest :

My research interests fall primarily into three categories as follows:

(1) reproductive epidemiology and biomonitoring.
(2) reproductive and development toxicity of environmental and dietary chemicals. (3) the cellular and molecular mechanisms of endometriosis.

 Research Interest
 Network
Lucio G Costa

Lucio G. Costa
Professor
Dept. of Environmental and Occupational Health Sciences
University of Washington,
USA
Tel. 206-543-2831
Fax 206-685-4696

Biography :

Dr. Lucio G. Costa is Professor of Toxicology at the University of Washington in Seattle and Professor of Pharmacology/Toxicology at the University of Parma Medical School. He received a doctorate in Pharmacology from the University of Milano in 1977, and was a postdoctoral fellow at the University of Texas at Houston. He is a member of several national and international professional organizations, a Fellow of the Academy of Toxicological Sciences, and a European Certified Toxicologist. He received various award for his scientific accomplishments, including the Achievement Award from the Society of Toxicology. He serves in various editorial capacities for several toxicology journals, and is an active manuscript and grant reviewer. Dr. Costa has been the member of dozens of panels and committees at the national and international level dealing with toxicology and risk assessment issues. He has chaired and/or organized symposia at dozens of scientific meetings in the United States and internationally. He has been teaching classes in the area of toxicology, neurotoxicology and pharmacology to graduate and medical students for 30 years. He keeps an active research program in the area of neurotoxicology, with over 400 publications, books and book chapters.

 Biography
Research Interest :

Neurotoxicology, pesticides, brominated flame retardants, oxidative stress, diesel exhaust neurotoxicity.

 Research Interest
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Wolfgang G Kreyling

Wolfgang G. Kreyling
External Scientific Advisor Institute of Epidemiology II
Helmholtz Zentrum München German Research Center for Environmental Health (GmbH)
Germany

Biography :

Wolfgang G. Kreyling is a biophysicist recently retired from coordinating all aerosol- and engineered nanoparticle related research of the Helmholtz Center Munich (HMGU) and heading the R&D program of the Institute of Lung Biology and Disease on dosimetry of ultrafine aerosol particles and engineered nanoparticles in the respiratory tract and secondary target organs like the cardiovascular and the central nervous system. In recent years I was much engaged with the International Society for Aerosols in Medicine (ISAM) and its President (2003-2005). Recently I served as a member of several expert panels of International (WHO, HEI), European (ESF, EU-DG SANCO, EFSA, ERS, EASAC) and German committees (DFG, BMBF, BMU). I am currently an associated editor of Particle & Fibre Toxicology as well as an editorial board member of several international aerosol and nanotechnology and –toxicology related journals.

 Biography
Research Interest :

Dr. Wolfgang G. Kreyling research interests range from aerosol sciences and nanoparticle technology to biophysics of the lungs reaching from the characterization of ambient aerosols to particle dosimetry and nanoparticle lung interactions on the level of the entire organism, cells like alveolar macrophages, and molecular compounds.

 Research Interest
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Steffen Ernst

Steffen Ernst
Head Translational Patient Safety
AstraZeneca Research & Development,
Global Medicines Development, Sweden
Tel. +46-31-77-61294
Fax +46-31-7763796

Biography :

Dr. Steffen W. Ernst joined AstraZeneca R&D Sweden in October 2002 and held various different roles in Pre-clinical Safety, and now heading the Global Section of Translational Patient Safety. Dr. Steffen W. Ernst aligning his training in Toxicology and medical background to develop the important area of Translational Medicine. Prior to joining AZ, Dr. Steffen W. Ernst worked >10 years in various other pharmaceutical companies (Hoechst, Boehringer-Ingelheim, Pfizer) as well as at the University of Munch Medical Centre. Dr. Steffen W. Ernst conducted his PhD training in Toxicology at the University of Kansas Medical Centre, USA and the German Gesellschaft für Umwelt und Gesundheit in Munich, Germany and received his medical degree from the Ludwig-Maximilian University in Munich, Germany. Dr. Steffen W. Ernst is US Board certified in Toxicology since 2001 and a EU registered Toxicologist through the British Toxicology Society since 2002.

 Biography
Research Interest :
 Research Interest
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Per Hartvig Honore

Per Hartvig Honore
Professor in Pharmacokinetics
Department of Pharmacology and Pharmacotheraphy
University of Copenhagen
Denmark

Biography :

Per Hartvig Honore was born in 1945. He received his Ph.D and Pharma D from Uppasala University in 1974. He worked as an Assistant Professor in 1977 and as an Adjunct Professor in 1989 form Uppsala university. He is working as a Professor in the Department of Pharmacology and Pharmacotheraphy from the University of Copenhagen, Denmark.

 Biography
Research Interest :

Research interest is primarily in clinical pharmacology/pharmacokinetics (analgesiology, pharmacokinetics, neuropharmacology and imaging). I have published more than 300 peer reviewed articles within analytical chemistry,clinical pharmacokinetics, analgesiology,neuropharmacology, neuro-imaging, cancer treatment and on management of infectious diseases.

 Research Interest
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Peter J O Brien

Peter J O Brien
Professor
University of Toronto
Canada
Tel. 416 978 2716
Fax 416 978 8511

Biography :

Peter J O Brien is working  as a Professor of Toxicology at Leslie Dan Faculty of Pharmacyin University of Toronto Canada. He has done his B.Sc. Honours, Biochemistry from the Department of Biochemistry, University College London, UK.
Done M.Sc. Radiobiology from the Department of Physics, Birmingham University, UK.He has done his Ph.D. Biochemistry, (Advisor, Prof. G. Hubscher) Department of Medical Biochemistry, Birmingham University, UK.
Post Doc fellowship is done along with Prof., Alistair Fraser, Department of Medical Biochemistry, Birmingham University, UK. He is a Senior Research Associate, Department of Medical Biochemistry, Birmingham University, UK.
He worked as an Associate Professor of Biochemistry, Department of Biochemistry, Memorial University of Newfoundland, St. John’s Nfld. He is now working as a Professor, Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy and Department of Pharmacology, Faculty of Medicine, University of Toronto.He has been as Graduate Chairman (1987-1999) and Associate Dean of Research Faculty of Pharmacy, University of Toronto. He worked as an editorial board member for the journals like Xenobiotica (1982-1995), Drug Metab. and Drug Interacns. He recieved various honors and awards like Recipient McNeil (Janssen-Ortho) Award for Pharmaceutical Sciences Research (1996).He has published over 250 scientific papers and 13 book chapters.

 Biography
Research Interest :

Peter J O Brien Research Interests are Biochemical and Molecular Toxicology, Mechanisms of Drug-Induced Cytotoxicity and Its Prevention.

 Research Interest
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Holme Hansen

Ebba Holme Hansen
Professor
Department of Pharmacology and Pharmacotherapy
University of Copenhagen
Denmark
Tel. 45 35 33 63 53
Fax 45 35 33 60 50

Biography :

Ebba Holme Hansen has been the Professor at the Section for Social Pharmacy, Faculty of Pharmaceutical Sciences since 1992 and has worked for the University since she earned her MSc degree in pharmacy in 1968. She has been the driving force behind the development of social pharmacy as an academic discipline.

 Biography
Research Interest :

Her focus is childrens medicine use, psychotropic medicines, adverse drug reactions and the experience and rationale of users in their use of medicines (the user perspective).

 Research Interest
 Network
Zanchi AC

Zanchi AC
Professor
Unilasalle University
Brasil

Biography :

Prof/ Dr. Ana Claudia Tedesco Zanchi has received his PhD in Sao Paulo University during the period of 2010 . Currently, she is working as researcher in Health Sciences of Porto Alegre in University and Professor at Unilasalle University, Porto Alegre, Brasil. She is serving as an editorial member of several reputed journals like Experimental Biology and Medicine (Maywood). She has authored many research articles in Environmental, Experimental Toxicology, animal models, nervous central system and oxidative stress.

 Biography
Research Interest :

Research interests are environmental, clinical and non essential metals toxicology, biochemistry of oxidative stress and animal behavioral studies.

 Research Interest
 Network
Om P Sharma

Om P Sharma
Professor of Biochemistry
Indian Veterinary Research Institute
India

Biography :

Dr. Om Sharma, Professor of Biochemistry is a Scientist-in-Charge at Indian Regional Station, Palampur, Kangra Valley (India). Dr. Sharma earned his PhD in Biochemistry at Central Drug Research Institute, Lucknow, India. Thereafter he joined Agricultural Research Service and has served in different capacities in IVRI since 1977. Dr. Sharma has an experience of 37 years in research and teaching and published 120 research papers and review articles. He has won Commonwealth Postdoctoral Award at the University of West London, Brunel  (1984-1985), Gold Medal of Panjab University Chandigrah, Best Paper Awards of the Society of Biological Chemists (India) on two occasions and of the Society of Toxicology (India). Dr. Sharma is a Fellow of the Society of Toxicology (India), member Editorial Board, International Journal of Animal Sciences, Asian Journal of Cell Biology, Asian Journal of Biochemistry, Research Journal of Microbiology, Indian Journal of Microbiology and life member of Indian Science Congress Association, Society of Biological Chemists, and Society of Toxicology.

 Biography
Research Interest :

Free radical biochemistry, plant toxins, plant secondary metabolites, and natural products in relation to animal toxicity (biochemistry, disposition, mechanisms).

 Research Interest
 Network
Li Hong yu

Li Hong yu
Associate Professor
The University of Arizona
USA

Biography :

Dr. Li received his PhD degree from the University of Tokyo. He did the postdoctoral training at Columbia University and Harvard University. Dr. Li has extensive experience in drug discovery and development with a particular focus on Oncology. He has led medicinal chemistry teams with over twenty chemists and collaborated with leaders in pharmacology toxicology pharmacokinetics pharmacy and intellectual property for the discovery of new experimental drugs IND. He and his team have successfully discovered three small molecule kinase inhibitors with acceptable toxicology profile that were tested in clinical trials. Dr. Li was the kinase platform drug design leader at Eli Lilly and was responsible for the generation of kinase inhibitors His broad expertise in the study of kinases and cancer will allow him to discover the next generation kinase inhibitors for use in cancer and Alzheimer’s disease.

 Biography
Research Interest :

Dr. Li’s research interest is drug discovery and development of kinase inhibitors for rare and/or neglected cancer diseases in a High-Throughput manner: 1) Selective Ret Kinase Inhibitor for Medullary Thyroid Cancer. 2) Selective Flt3 kinase Inhibitor for the AML (Acute Myeloid Leukemia). 3) mTor Inhibitors and Its Prodrug for the Skin Cancer Chemoprevention. To discover active hits, a novel type of kinase fragment library will be generated in a High-Throughput manner. This kinase fragment library will be designed to overcome most of issues concerning kinase fragment libraries. Compounds identified from the library as an active will be further optimized for better activity and toxicity profiles. The optimization will be done through the library synthesis approach, rather than the industry standard approach of solving SAR (structure-activity relationship) problems one molecule at a time. The one-by-one approach may work well in the beginning of the sequence of the drug discovery value chain, but you may run the risk of encountering the initial problems when trying to solve the next problem. One-cycle library iteration will produce a wide range of SAR information including toxicity for the next library design and production. Three to five cycle iterations of libraries will generate advanced compounds with properties to produce the desired in vivo efficacy with acceptable toxicity profile. The library design approach aided by the computer modeling and calculation will focus on solving any unforeseen SAR problems for each cycle.

 Research Interest
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uoping Zhang

Luoping Zhang
Associate Adjunct Professor
Division of Environmental Health Sciences
University of California at Berkeley
USA
Tel. 510 643 5189
Fax 510 642 0427

Biography :

Dr. Luoping Zhang is an Associate Adjunct Professor of Toxicology in the Division of Environmental Health Sciences, School of Public Health at UC Berkeley.  Dr. Zhang obtained her B.S. in Chemistry from Wuhan University and M.S. in Biochemistry from Huazhong University of Science and Technology, Wuhan, China.  After completing her research fellowship, which was awarded from The Third World Academy of Science in Italy. She moved to Vancouver and received her Ph.D. in Simon Fraser University, British Columbia, Canada.  She is very active in the scientific community, being a member of Society of Toxicology (SOT), NorCal SOT (Northern California chapter), Environmental Mutagenesis Society and American Association of Cancer Research.  She belongs to an International research group that investigates benzene-induced toxicity and leukemogenesis, and conducts many studies on environmental exposure related issues in China with her collaborators. Currently, she resides in Berkeley and co-directs the Gene and Environment Laboratory.

 Biography
Research Interest :

Dr. Zhang’s research focuses on understanding the molecular mechanisms of bone marrow toxicity and carcinogenesis caused by benzene (BZ) and other toxic chemicals including butadiene (BD), formaldehyde (FA), tricholoroethylene (TCE) and arsenic (As). Her investigations have mainly involved in the detection of biomarkers associated with these chemical exposures in molecular epidemiological studies conducted with national and international collaborators. Her group employs and develops novel high-throughput technologies, such as, molecular cytogenetics (OctoChrome FISH, fluorescence in situ hybridization), single-cell genetic analysis (SCGA) and array-based toxicogenomic technologies to further understand the causes and mechanisms of leukemia and lymphoma associated with exposure to environmental pollutants. Most recently, she has incorporated a systems biology approach, leading research efforts to apply toxicogenomics such as gene expression profiling and epigenetics in molecular epidemiology studies and RNAi (RNA interference) in human cell culture studies of toxic chemical exposure.
 

 Research Interest
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Michael Iba

Michael Iba
Associate Professor
Department of Pharmacology and Toxicology
Rutgers University
USA
Tel. 732 445 6910
Fax 732 445 6905

Biography :

Dr. Iba received his undergraduate degree in chemistry and biology at the University of Wisconsin and his PhD in pharmacology at the University of Illinois. He did postdoctoral work at the University of Minnesota and is currently in the Department of Pharmacology at the Ernest Mario School of Pharmacy, Rutgers University. He is a member of several scientific societies, including  the American Society for Pharmacology and Experimental Therapeutics, American Association for Cancer Research, and  International Society for the Study of Xenobiotics.  Has served as a consultant on national and international scientific review panels and has reviewed extensively for many scientific reasearch journals, including editorial board memberships. He is actively engaged in research and teaching on, and has published in the areas of  inhalation toxicology; toxicology of mixtures, including tobacco smoke and other combustion emissions;  mutagenesis; developmental toxicology; pharmacogenetics; metabolism and toxicology of therapeutic drugs.

 Biography
Research Interest :

He is actively engaged in research and teaching, and has published in the areas of  inhalation toxicology; toxicology of mixtures, including tobacco smoke and other combustion emissions;  mutagenesis; developmental toxicology; pharmacogenetics; metabolism and toxicology of therapeutic drugs.

 Research Interest
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Randall L Davis

Randall L Davis
Associate Professor
Department of Pharmacology and Physiology
Oklahoma State University
USA
Tel. 918 561 8408
Fax 918 561 561 5798

Biography :

Dr. Davis received his BS in biomedical sciences from Oklahoma State University in 1990. He remained at Oklahoma State University until 1994 when he received a MS in Zoology. Dr. Davis then earned a PhD in nutrition from Texas Tech University in 1998. Upon completion of his doctoral degree he trained for six years 1998 to 2004 in Pharmacology and Neuroscience as a Postdoctoral Research Associate at the Texas Tech University Health Sciences Center and was an Instructor and course coordinator in the nutrition program at Texas Tech University. During this period he received a National Research Service Award from the National Institutes of Health. Additionally during these training years he received numerous academic scholarships teaching awards and young investigator awards. In 2004 Dr. Davis was appointed Assistant Professor of Pharmacology at the Oklahoma State University Center for Health Sciences OSUCHS in Tulsa OK. Then in 2010, Dr. Davis was promoted to Associate Professor with tenure at OSUCHS. Dr. Davis has served as the Managing Editor for the special issue: Neuroinflammation: modulation by drugs of abuse published in Frontiers in Bioscience and is the Editor-in-Chief of the International Journal of Cytokine Mediator Research. Dr. Davis peer reviews manuscripts for numerous scientific journals and has served as an ad hoc reviewer for the National Institutes of Health Alzheimer’s Association and Kentucky Tobacco Research Development Center. In addition to his teaching responsibilities in the Medical and Biomedical Sciences Graduate curricula at OSUCHS and other professional activities. Dr. Davis research lab is interested in the role of neuroinflammation in neuropathologies including neuroAIDS parkinson’s disease and autism. In particular his research efforts are focused largely on 1. understanding the effects of alcohol abuse on inflammatory signaling in human astroglial cells 2. characterizing the novel antiinflammatory actions of opioid compounds and 3. understanding the effects of heavy metals exposure on neuroimmune signaling.

 Biography
Research Interest :

Dr. Davis’s research lab is interested in the role of neuroinflammation in neuropathologies including neuroAIDS, parkinson’s disease and autism. In particular, his research efforts are focused largely on 1) understanding the effects of alcohol abuse on inflammatory signaling in human astroglial cells, 2) characterizing the novel, anti-inflammatory actions of opioid compounds and 3) understanding the effects of heavy metals exposure on neuroimmune signaling.

 Research Interest
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Gerald M Higa

Gerald M Higa
Associate Professor
School of Pharmacy and Medicine
West Virginia University Morgantown
USA
Tel. 304 293 1461
Fax 304 293 7672

Biography :

Gerald M. Higa is working as an Associate Professor in the Schools of Pharmacy and Medicine, and the Mary Babb Randolph Cancer Center, West Virginia University.

 Biography
Research Interest :

Delineating the molecular mechanisms and signaling pathways that regulate chemotherapy-induced nausea and vomiting, comparing the effects of transfused RBC and rh-EPO on erythroid progenitors, and reducing chemotherapy-induced neurologic toxicity through the vitamin D pathway.

 Research Interest
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Collin A Hovinga

Collin A Hovinga
Associate professor
University of Tennessee Health
Le Bonheur Children’s Medical Center
USA
Tel. 901 287 5301
Fax 901 448 6064

Biography :

Dr. Hovinga completed his Bachelor of Science Degree in Biology (1991) and Doctor of Pharmacy (1997) degrees from Creighton University in Omaha, Nebraska.  After which he pursued a Residency and Fellowship in Pediatric Pharmacotherapy (1997-2000) with emphasis in Pediatric Neuroscience at the University of Tennessee, Memphis, LeBonheur Children’s Medical Center.  He has had a Fellowship at the Food and Drug Administration Office of Clinical Pharmacology (2009) and a Masters of Epidemiology from the University of Tennessee Health Science Center (2010).  He is currently Director of Research at Dell Children’s Medical Center and Associate Professor of Clinical Pharmacy at UT Austin School of Pharmacy. Doctor Hovinga has been active in studying the genetic effects on the susceptibility of neonates to hypoxia-induced seizures and in studying the pharmacogenetics of medications in the treatment of epilepsy and autism.  Dr. Hovinga is recognized as an expert in neuropharmacology.  Dr. Hovinga has had leadership roles in neuroprotective drug pharmacology NIH projects (Clinical Investigations for Neuroprotective Agents in Parkinson’s Syndrome (CINAPS)) and for Huntington’s Disease (SET-HD).  Dr. Hovinga’s understanding of developmental pharmacology and pediatric brain injury has made him unique in the pharmacology arena and has led to him being a journal reviewer and an invited speaker at many national organizational meetings.

 Biography
Research Interest :

Pediatric Pharmacotherapy, Pediatric Neuroscience.

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Robert Lee Page II

Robert Lee Page II
Associate Professor
Department of Clinical Pharmacy
University of Colorado
USA
Tel. 720 724 2626

Biography :

Robert L Page II, Pharm.D, MSPH, is an Associate Professor with the Department of Clinical Pharmacy and Physical/Rehabilitative Medicine at the University of Colorado Denver, Schools of Pharmacy and Medicine Aurora, CO, and the Clinical Pharmacy specialist for the Division of Cardiology and Heart Transplantation. Dr. Page received his Bachelors of Science in Biology and Chemistry from Furman University Greenville, Bachelors of Science in Pharmacy and Doctor of Pharmacy degrees from the Medical University of South Carolina Charleston, Masters of Science in Public Health with an Epidemiology focus from the University of Colorado School of Medicine Denver, CO, and completed his specialty residency in pharmacotherapy from MUSC. He is presently a Doctor of Philosophy student in Health Services Research and Health Policy in the Colorado School of Public Health Aurora, Colorado. He is a Board Certified Pharmacotherapy Specialist with Added Qualifications in Cardiology, a Certified Geriatric Pharmacist, and a Fellow for the following organizations: the American College of Clinical Pharmacy, the American Heart Association Council on Clinical Cardiology, the American Society of Consultant Pharmacists, and the American Society of Health System Pharmacists. Dr. Page has authored several abstracts, journal articles, and book chapters in the areas of cardiovascular pharmacotherapy, as well as, been honored with numerous teaching awards.

 Biography
Research Interest :

Dr. Page’s research interests consist of drug-drug and drug-herbal interactions, medication adherence, and pharmacotherapy complications in the heart transplant recipient and heart failure patient.

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Karel Allegaert

Karel Allegaert
Associate Professor
University Leuven
Belgium

Biography :

Karel Allegaert graduated from the University Leuven, Belgium in 2000 as paediatrician-neonatologist. After an additional training at Sophia Children’s Hospital in Rotterdam, he was appointed as clinical consultant neonatology at the University Hospitals Leuven. After his PhD thesis on neonatal analgesia (2002-2005), he further developed his clinical research in the field of neonatal pain treatment and developmental pharmacology in neonates and was appointed as associated professor at the same university (2005-ongoing).
His current clinical research is supported by a grant of the national research council (Fund for Scientific Research, Flanders (Belgium) by a Fundamental Clinical Investigatorship (1800209 N, 2008-2012). This clinical research resulted in about 140 papers published in international peer reviewed journals, conferences proceedings and book chapters and was recently (2009) awarded the Galenus price for research in clinical pharmacology and the Govaerts price for clinical toxicology (2009) of the Royal Academy of Medicine of Belgium.

 

 Biography
Research Interest :

Developmental Pharmacology/toxicology (neonatal, child).

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Vivian Wy Lee

Vivian Wy Lee
Associate Professor
Chinese University of Hong Kong
China

Biography :

Dr. Vivian Lee is currently serving as an Associate Professor in the School of Pharmacy and the Assistant Dean (Student Affairs) of the Faculty of Medicine, Chinese University of Hong Kong. She joined the School of Pharmacy since 2000. Before her current appointment, she had worked as a hospital clinical pharmacist at an acute-care hospital, Cedars-Sinai Medical Center, in Los Angeles. Dr. Lee received her bachelor of sciences degree in Biochemistry at the University of California, Los Angeles (UCLA) and her doctor of pharmacy degree in the School of Pharmacy, University of Southern California (USC). After completion of her pharmacy training, she had pursued post-doctoral training in Pharmacy Practice residency for one year at the Huntington Memorial Hospital in Pasadena, USA. Her specialty is in clinical pharmacy.
Dr. Lee is dedicated for the clinical pharmacy development.  She started the first clinical pharmacy clerkship program in the undergraduate program as well as the overseas student exchange in clinical pharmacy with USC.  In addition, she tries to expand the roles of pharmacist through various innovative ways including the launch of the first interactive online drug information platform in Hong Kong-Ask My Pharmacist Online University Led drug Enquiry Platform (AMPOULE), the Paediatric Health: easyAccess Resources on Medicines (PHARM) and the community pharmacy outreach program to cope with the demands of pharmaceutical careto improve medication adherence and chronic disease management in elderly patients of Hong Kong.

 Biography
Research Interest :

Dr. Lee research interest is in clinical pharmacy outcomes research in particular to chronic disease management utilizing the skills of clinical pharmacy, pharmacoeconomics and pharmacogenomics to improve patient care.

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John F Gamble

John F Gamble
Consultant, Somerset
USA

Biography :

Dr. Gamble received his Phd in Environmental Science and Industrial Hygiene at the University of North Carolina School of Public Health in Chapel Hill, NC in 1975.  This was a period when the SPH was investigating the health status of workers in the rubber industry.  Subsequently he was Epidemiology Section Chief in NIOSH at Morgantown, WV studying health among miners and workers exposed to diesel exhaust, sulphuric acid, coal and industrial talc.  He worked at Exon Mobil Biomedical Sciences Inc studying primarily asphalt and air pollution.  Currently he is working as a consultant and conducting literature research on issues including asbestos, non-asbestiform amphiboles, diesel exhaust, silica, coal.  He served as industry observer at IARC Monographs 68 and 100C and has chapters on Occupational Epidemiology in 3 different editions of Patty’s Industrial Hygiene.  He has authored about 100 research articles and book chapters.

 Biography
Research Interest :

John F Gamble research interests are epidemiology, particularly occupational epidemiology and causality.

 

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Wong Ho Lun

Wong Ho Lun
School of Pharmacy
Temple University
USA

Biography :

Dr. Wong is Assistant Professor of Pharmaceutical Sciences at Temple University, School of Pharmacy. After earning his profession degree of Pharmacy and PhD in Pharmaceutical Sciences at University of Toronto, he completed his postdoc training at Ohio State University. Dr. Wong research focuses on the use of nanomedicine to improve the therapeutic efficiency and safety of anticancer compounds in particular the strategic use of lipid based nanosystems to deliver macromolecules and cytotoxic small molecule compounds alone or in combinations for drug resistant cancer treatment.

 Biography
Research Interest :

Novel drug delivery system design 2. Evaluation of efficacy and toxicity of nanomedicine-based cancer treatments 3. Anticancer therapy integrating molecular therapeutics (e.g. RNAi therapy) and conventional chemotherapy (e.g. cytotoxic anticancer compounds).

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Jaehyung Cho

Jaehyung Cho
Department of Pharmacology
University of Illinois College of Medicine
USA

Biography :

Jaehyung Cho received his Ph.D from the University of Wisconsin-Madison in the field of Molecular and Cellular Pharmacology. He did his Post Doctoral degree from Harvard Medical School in the field of Vascular Biology. He was working as an Assistant Professor in the Department of Pharmacology, University of Illinois.

 Biography
Research Interest :

The research interest of my laboratory is to understand the molecular mechanisms of the initiation step of vascular diseases such as thrombosis and inflammation. We are currently focusing on the role of protein disulfide isomerase (PDI) in integrin-mediated platelet and leukocyte functions. These studies will be performed mainly using multi-fluorescence intravital microscopy to monitor expression kinetics of target molecules at the site of vascular injury in various knockout mice. A better understanding of the molecular mechanism of the initiation of vascular diseases could lead to the development of effective therapeutics for the prevention in vascular diseases.

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Hyun Young Jeong

Hyun Young Jeong
Department of Biopharmaceutical Sciences
University of Illinois
USA
Tel. 312 996 8639
Fax 312 996 0098

Biography :

Hyun Young Jeong is Assistant Professor of Pharmacokinetics in the Department of Pharmacy, Practice and Biopharmaceutical Sciences at the University of Illinois at Chicago. She received BS degree in Pharmacy from Seoul National University and PharmD/PhD from University of Illinois at Chicago. Her research interests are in 1.The altered pharmacokinetics of drugs in pregnant women 2. Regulation of hepatic drug metabolism and 3. Role of pharmacokinetics in preclinical drug development. Currently she is investigating the effects of pregnancy hormones on expression of cytochrome P450 enzymes and involvement of nuclear receptors in hormonal regulation of drug metabolizing enzymes.

 Biography
Research Interest :

Altered pharmacokinetics of drugs during pregnancy, Regulation of expression and activity of hepatic drug metabolizing enzymes, Hormone pharmacology involving estrogen, progesterone, and somatotropins.

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Claire M Mach

Claire M Mach
University of Houston College of Pharmacy
USA
Tel. 713 795 8373
Fax 713 795 8383

Biography :

Claire M. Mach, Pharm.D is an Assistant Professor at the University of Houston in the College of Pharmacy and a Clinical Specialist in Gynecologic Oncology at Ben Taub General Hospital in Houston, Texas.  She received a BS in Biochemistry at Texas, A&M University in 1999 and her Pharm.D from the University of Houston, College of Pharmacy in 2006.  She completed a three year Oncology Translational Research Fellowship at the University of Texas M.D., Anderson Cancer Center in 2009.

 Biography
Research Interest :

My research utilizes high throughput screening strategies to identify novel therapeutic and diagnostic targets in ovarian cancer and uterine papillary serous carcinoma (UPSC).  I focus primarily on the role of microRNAs which are small, noncoding RNA transcripts that play a critical role in regulating diverse patterns of gene expression.  In conjunction with Dr. Matthew L. Anderson, MD, PhD at Baylor College of Medicine, we are currently dissecting the roles of microRNAs identified in regulating ovarian cancer and UPSC growth and metastasis.  These insights will be used to develop novel treatment strategies for these deadly diseases.

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Monath Sanjaya Kuruppu

Monath Sanjaya Kuruppu
Department of Pharmacology and Biochemistry
Monash University
Australia

Biography :

I obtained my PhD in Pharmacology from Monash University in Australia. My research focussed on the pharmacological characterisation of peptide neurotoxins from Australian and Papua New Guinean snake venoms. I also examined the efficacy of commercially available antivenoms in neutralising the effect(s) of these toxins. My postdoctoral training was conducted in the Department of Biochemistry & Molecular Biology (Monash University). The research conducted focused on proteases that play a key role in the cardiovascular system and their substrates. My current research focuses on understanding the role of above mentioned proteases in the pathogenesis of cardiovascular diseases, with a particular emphasis on clinical translation.

 Biography
Research Interest :

Identification of specific inhibitors of Endothelin Converting Enzyme-1 from natural sources such as snake venoms, and determining the cross reactivity of locally produced antivenoms with toxins from snakes in different geographical regions.

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Donghai Xiong

Donghai Xiong
Department of Pharmacology and Toxicology
Medical College of Wisconsin
USA

Biography :

Dr. Xiong graduated from Creighton University in 2007 with a Ph.D. in Biomedical Science. He has made Internationally recognized achievements in genetic studies of human complex diseases and complex traits and published 67 peer-reviewed articles in prestigious international journals, 2 book chapters published by world-famous scientific publishers - Humana Press and World Scientific and made 26 presentations in various international scientific meetings. He is the recipient of multiple honors for his research, such as Webster Jee Young Investigator Award. He has been on faculty at University of Missouri – Kansas City and Medical College of Wisconsin for the past several years. As the most prestigious expert in his field, he has been invited to review articles for the top ranked professional journals in the human genetics and disease research fields such as Human Molecular Genetics, Spine, Journal of Bone and Joint Surgery, International Journal of Obesity, Journal of Clinical Endocrinology and Metabolism, BMC Genetics, and Journal of Musculoskeletal and Neuronal Interactions.

 Biography
Research Interest :

Exons are short, functionally important sequences of DNA which represent the regions in genes that are translated into protein. It is estimated that the protein coding regions of the human genome constitute about 85% of the disease-causing mutations. Exome sequencing has taken centre stage in cancer profiling. My primary research interest is to utilize this state-of-the-art technology to analyze multiple tumor-normal pairs to identify the genes underlying lung cancer. Currently we have finished whole exome sequencing and analysis of 14 samples taken from both the lung cancer tissue and the adjacent normal tissue from each of the seven lung cancer subjects. By comparing the genetic variants called from tumor and normal samples, we identified a pool of candidate genes associated with lung cancer. We are also collaborating with TCGA (The Cancer Genome Atlas) to analyze additional 81 samples from 43 lung cancer patients using exome sequencing technology. The follow-up molecular validation of the identified genetic variants underlying lung cancer is also ongoing. Our aim is to find and confirm as many as possible the somatic mutations associated with lung cancer. I am particularly interested in developing and applying multiple statistical methods for the fast and robust identification of genetic mutations underlying human cancer.

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Alan H Hall

Alan H Hall
Department of Health & Human Services
Colorado School of Public Health
USA

Biography :

Alan H. Hall, M.D. is a board certified Medical Toxicologist and is President and Chief Medical Toxicologist of Toxicology Consulting and Medical Translating Services, Inc., Laramie, Wyoming.  He is also Clinical Assistant Professor at the Colorado School of Public Health, Denver, Colorado, and was formerly Clinical Assistant Professor of Preventive Medicine and Biometrics at the University of Colorado School of Medicine and Assistant Professor of Pediatrics.  Dr. Hall was formerly Research Assistant Professor in the Division of Medical Toxicology, Department of Emergency Medicine, Texas Tech University Health Sciences Center, El Paso, Texas.  He received his undergraduate degree from Indiana University South Bend, South Bend, Indiana from which university he has Division and University-wide Distinguished Alumnus awards.  He received his Doctor of Medicine degree from the Indiana University School of Medicine, Indianapolis, Indiana.  Dr. Hall has been in General Practice, trained in Anesthesiology, and practiced Occupational and Environmental Medicine and Emergency Medicine.

 Biography
Research Interest :

He has a particular interest in Occupational and environmental chemical exposures, toxic gases, toxic terrorism preparedness and prevention, Advanced Hazardous Materials Life Support (AHLS verified Provider and Instructor and member of the Scientific Advisory Committee), decontamination of skin/eye chemical splashes, and especially cyanide poisoning and its antidotal treatment.

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Stark Martha

Stark Martha
Department of Psychiatry
Beth Israel Deaconess Medical Center
Harvard Medical School
USA

Biography :

Martha Stark is a graduate of harvard medical school, is a holistic psychiatrist and Psychoanalyst in private practice in boston and clinical instructor in psychiatry at harvard medical school. In addition, she serves on the faculty of the continuing education program in the Department of psychiatry at the beth israel deaconess medical center, is adjunct faculty at the Center for psychoanalytic studies at massachusetts general hospital, and teaches in the continuing Education programs at the massachusetts school of professional psychology and the Smith college school for social work.

 Biography
Research Interest :

Psychoanalytic studies.

 Research Interest
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Kenneth Ndebele

Kenneth Ndebele
Medical Scientist
Dana Farber Cancer Institute Harvard Medical School
USA

Biography :

Dr. Kenneth Ndebele received his PhD in Immuno–Toxicology. Currently, he is working as a Medical Scientist at Dana Farber Cancer Institute Harvard Medical School in Boston MA.  He is serving as an editorial member of several reputed journals like Journal of Clinical Toxicology, and he is member of American Society of Cell Biology. Dr. Kenneth Ndebele has co-authored over 25 research articles.

 Biography
Research Interest :

The Cancer Immunology, Target Identification and Validation laboratory focuses on the molecular and processes governing the development of cancer. The laboratory of Dr. Kenneth Ndebele takes an integrated genomics and proteomics systems approach to (a) discover and validate candidate oncogenes and tumor suppressor genes using known and novel gain-of-function and loss-of-function cell-based in vitro and in vivo assays (b) elucidate the mechanisms of biomarkers driving cancer progression (c) the discovery of novel cancer therapies directed against newly discovered and rigorously validated oncogenes.

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Annette C Rohr

Annette C Rohr
Department of Air Quality and Health
Electric Power Research Institute (EPRI)
USA

Biography :

Dr. Annette Rohr received her doctoral degree in Environmental Health from the Harvard School of Public Health. She is currently employed at the Electric Power Research Institute, where she manages research activities related to air quality and health, as well as potential health and environmental impacts associated with future electricity generation technologies.

 Biography
Research Interest :

Air pollution toxicology and epidemiology, toxicology of amines and their degradation products, general environmental toxicology.

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 Acceptance Letter
Dongsheng Cai

Dongsheng Cai
Department of Molecular Pharmacology
Albert Einstein College of Medicine
USA

Biography :

Dongsheng Cai is an assistant professor of physiology at the UW School of Medicine and Public Health.

 Biography
Research Interest :

Dongsheng Cai investigating how intracellular stress and pro-inflammatory pathways in the nervous system are involved in the neural/neuroendocrine mechanisms of various nutritional diseases (obesity, diabetes, and cardiovascular diseases) and aging-related diseases (eg, neurodegenerative diseases).and the interactions between pro-inflammatory signaling cascades and neuronal regulatory network that underlie the development of obesity, anorexia, diabetes, cardiovascular diseases, and aging-related disorders.

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Yanfeng Zhang

Yanfeng Zhang
Biological Sciences Division
Pacific Northwest National Laboratory
USA
Tel. 509 372 4790

Biography :

Dr. Yanfeng Zhang has received his Ph.D. in Genetics from Michigan State University during the period of 2004 to 2009. Currently, he is working as a Research Associate in Pacific Northwest National Laboratory. He has authored more than 10 research articles and presented several times on international scientific conferences. He is a member of American Association of the Advancement of Science.

 Biography
Research Interest :

Analytical Biochemistry, Microbiology, Cell Biology and Toxicology, Protein Chemistry.

 Research Interest
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Masayuki Ohyama

Masayuki Ohyama
Department of Environmental Health
Osaka Prefectural Institute of Public Health
Japan
Read Interview session with Masayuki Ohyama

Biography :

Currently, Masayuki Ohyama is working as a senior researcher in Osaka Prefectural Institute of Public Health. He has successfully completed his Administrative responsibilities as pharmacist. He has authored some research articles. For example, “Effect of size of man-made and natural mineral fibers on chemiluminescent response in human monocyte-derived macrophages. Ohyama M, et al. Environmental Health Perspectives. 2001. 109:1033-1038.”, “A comparison of the production of reactive oxygen species by suspended particulate matter and diesel exhaust particles with macrophages. Ohyama M, et al. Inhalation Toxicology. 2007;19 Suppl :157-160.”, “Effects of nitrous acid exposure on pulmonary tissues in guinea pigs. Ohyama M, et al. Inhalation Toxicology. 2010. 22:930-936.”, etc.  He is a member of Japan Society for Atmospheric Environment and Japanese Society of Public Health.

 Biography
Research Interest :

Air pollutant, Experiment of gas exposure to animal, Asian dust.

 Research Interest
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Kanji Yamasaki

Kanji Yamasaki
Chemical Evalution and Research Institute
Japan
Read Interview session with Kanji Yamasaki

Biography :

Kanji Yamasaki was born in Nagasaki, Japan. 1976 M.Sc., Veterinary Medicine, University of Tottori. 1989 Ph.D., in Veterinary Medicine, University of Hokkaido. 1990 the Progress Award from the Japanese Association for Laboratory Animal Science. 1991-present Diplomete of the Japanese College of Veterinary Pathologist. 1993-present Diplomete of the Japanese Society of Toxicological Pathology. 1999-2007 the OECD VMG-mammalian member. 2008 Lecturer in Ochanomizu University, 2009-present Lecture in Meiji University, 2009-present Risk Communication Expert Committee member of the Food Safety Commission of Japan. 2010 Lead Guest Editor for special issues of Journal of Toxicology. Editorial Board of ISRN Toxicology.

 Biography
Research Interest :

Specialized field is the toxicology, endocrine-related effects, experimental pathology, and risk assessment of chemicals, and research field is toxicity focused on studies of endocrine disrupting chemicals, carcinogenesis, pathology of bone and cartilage disorders.

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Mamiko Koshiba

Mamiko Koshiba
Saitama Medical University
Japan

Biography :

Dr. Mamiko Koshiba is the visiting associate professor of Saitama Medical University who was previously the visiting associate professor of Tokyo University of Agriculture and Technology. Her research interests have been in higher-order brain functions of psychology and psychiatry. After her carrier of clinical industrial engineer, she has kept her concentrations in social development from infant to elderly by novel methodology to bridge between subjectivity and objectivity. She showed the strategy with two experimental animal models, domestic chicks and common marmosets for preclinical evaluation.

 Biography
Research Interest :
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Qing Yan

Qing Yan
Chief Scientist
PharmTao
Canada

Biography :

Dr. Yan has extensive research experience in biomedical informatics, including more than 10 years as a group leader in the biopharmaceutical industry. Dr. Yan has published many research papers and edited four biomedical books, including "Systems Biology in Drug Discovery and Development: Methods and Protocols" and "Pharmacogenomics in Drug Discovery and Development". Dr. Yan received a Ph.D. degree in Biological and Medical Informatics from the University of California San Francisco (UCSF).

 Biography
Research Interest :

Bioinformatics; health informatics; medical informatics; systems biology; pharmacogenomics; immunology; neuroscience; immunoinformatics; neuroinformatics; personalized medicine; translational medicine.

 Research Interest
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Mathieu Vinken

Mathieu Vinken
Department of Medicine and Pharmacy
Vrije Universiteit Brussel
Belgium
Tel. 322 477 4587
Fax 322 477 4582

Biography :

Mathieu Vinken graduated as a pharmacist and subsequently obtained the degree of Doctor in Pharmaceutical Sciences at the Vrije Universiteit Brussel (VUB) - Belgium. He is a European registered toxicologist and is trained as a chemical risk assessor. Dr. Vinken is author of more than fifty scientific publications in peer-reviewed journals and books and is involved in several European research projects in the field of liver-based in vitro modelling. He is currently a postdoctoral researcher at the Department of Toxicology of the VUB-Belgium and his research is situated in the field of experimental and molecular in vitro toxicology.

 Biography
Research Interest :

His research is situated in the field of experimental and molecular in vitro toxicology.

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Amol Suryawanshi

Amol Suryawanshi
Department of Ophthalmology
Tufts University School of Medicine
USA

Biography :

Dr. Suryawanshi received his DVM degree from Bomaby Veterinary College, India and MS in Biochemistry from Indian Veterinary Research Institute, India. He then completed his PhD in Comparative & Experimental Medicine at the College of Veterinary Medicine, The University of Tennessee. His doctoral research work focused on understanding the role of IL-17A and Th17 cells in herpes simplex virus 1-induced corneal immunopathology. As a postdoctoral research fellow at Tufts University School of Medicine, he is studying the role of host innate and adaptive immune response in mediating corneal pathology and vision impairment against various microbial infections of the cornea.

 Biography
Research Interest :

Host Pathogen Interaction and associated immunopathology, Infectious Blindness, Angiogenesis, Inflammation, Corneal Immunopathology, Infectious Diseases. Identifying novel molecular and cellular targets for pharmacological intervention of inflammatory conditions.

 Research Interest
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Maryam Akhgari

Maryam Akhgari
Head of Forensic Toxicology Laboratory
Legal Medicine Organization
Iran

Biography :

Born in Tehran, Iran in 1971, got his Pharm D. from Tehran University of Medical Sciences (TUMS) in 1996 and Ph.D. (Toxicology/Pharmacology) from TUMS in 2003. She had been one of the members of Irans Drug & Poison Information Centers from 2000 to 2003. In 2005 she became Assistant Professor in Legal Medicine Research Center of Iran. She has been the Head of Forensic Toxicology Laboratory in Legal Medicine Organization of Iran, Tehran since 2005. The outcomes of her researches are more than 20 papers in English and Farsi. She has supervised more than 5 Doctorate students thesis. She is working on forensic and toxicology science fields like drug related deaths, profile of abused substances in Iran, toxicology and histopathology study of poisons.

 Biography
Research Interest :

She is working on forensic and toxicology science fields like drug related deaths, profile of abused substances in Iran, toxicology and histopathology study of poisons.

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Campos Vaquero

Campos Vaquero
Department of Cellular and Molecular Medicine
Centre for Biological Research, CSIC
Spain

Biography :

Dr. Campos received a Ph.D with honors in Biochemistry and Molecular Biology from the University Complutense of Madrid in 2011. He began work in the Centre for Biological Research of the CSIC in the Department of Cellular and Molecular Medicine. He is a current member of the Bílbilis Foundation for the Innovation and Research in Medical Hydrology and Balneotherapy since 2008.

 Biography
Research Interest :

Clinical toxicology; Oxidative stress in a number of human conditions, such as: Down syndrome, Alzheimer disease, exercise, smoking, aging, etc.; Biomarkers of oxidative stress; Total antioxidant capacity assessment; Balneotherapy and sulphurous water.

 Research Interest
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Ruben K. Dagda

Ruben K Dagda
Assistant Professor
Department of Pharmacology
University of Nevada
USA
Read Interview session with Ruben K. Dagda

Biography :

Ruben K. Dagda, Ph.D., received his doctoral training at the University of Iowa and his postdoctoral training at the University of Pittsburgh School of Medicine. He is currently investigating the molecular mechanisms that lead to mitochondrial dysfunction and oxidative stress in cell culture, tissue and animal models of Parkinson\s disease. He has authored in multiple research manuscripts and review articles in the areas of toxicology, toxinology, mitochondrial function, and neurobiology. As an Assistant Professor at the University of Nevada School of Medicine (UNSOM), he is committed to the training and education of undergraduate, graduate students and postdocs in his lab. His main research goals are to elucidate the prosurvival signaling pathways that regulate mitochondrial function, transport and turn-over in neurons and how aging and neurodegenerative diseases negatively impact these processes. The end goal is to develop novel small molecular drugs that can reverse neurodegeneration and elevate mitochondrial function in age-related neurodegenerative diseases.

 Biography
Research Interest :

Neurons rely on functionally efficient mitochondria to power critical neuronal functions. Given that impaired mitochondrial turnover and dysfunction underlie the etiology of many neurodegenerative diseases, understanding how reversible phosphorylation at the mitochondria regulates mitochondrial function and turnover will lay the basic groundwork for developing future “mitoprotective” therapies that reverse mitochondrial dysfunction and neurodegeneration. At the postsynaptic compartment, PINK1 and PKA remodel dendritic arbors in developing neurons and regulate mitochondrial transport. We are examining how these two kinases interact at the mitochondria and at the neurites to regulate mitochondrial function, dendritic morphology and survival. A second are of interest it to determine how mitochondrial turnover (mitophagy) is regulated by reversible phosphorylation mediated by phosphatases and kinases. A third project is to synthesize new reagents that can activate prosurvival signaling pathways at the mitochondrion as mitochondrial therapy for reversing mitochondrial pathology induced by neurodegenerative diseases.

 Research Interest
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Ong Yong Kwang Gene

Ong Yong Kwang Gene
Department of Paediatric Emergency Medicine
Kandang Kerbau Hospital
Singapore

Biography :

Dr Gene Ong received his MBBS in National University of Singapore during the period of  1995-2000. He successfully obtained his postgraduate qualifications (MRCPCH, UK) in Paediatric Medicine in 2004. Currently, he is working as a Consultant in the Department of Paediatric Emergency Medicine in Kandang Kerbau Hospital, Singapore. As part of his interest in paediatric toxicology, he is part  the Singapore Ministry of Health Clinical Guidelines Development Committee for Acute Poisonings, auditor and member in the Toxicology Society of Singapore, member of the Hazmat Medical Life Support Course Scientific Committee and is a  member of the Asia Pacific Association of Medical Toxicology. He is also serving as a member of the National Resuscitation Council, Paediatric Subcommittee (Singapore), Emergency Airway Management Course Scientific Committee, KK Hospital Resuscitation and Emergency Code Committee and core member of the State of Emergency Medical Care in Singapore Workgroup and chairperson of its Paediatric Emergency Care Subcommittee.
He is a clinical tutor in paediatric medicine for Yong Loo Lin Medical School and Duke’s Medical University, Singapore and is a faculty member in the Accreditation Council for Graduate Medicine in Emergency Medicine, Joint Committee on Basic Specialty Training in Emergency Medicine, Singapore.
Dr. Ong is also a course instructor in Adanced Cardiac Life Support, Advanced Trauma Life Support, Advanced Resuscitation in Children, Emergency Airway Management and Hazmat Medical Life Support Courses.
 

 Biography
Research Interest :

Paediatric resuscitation, Paediatric toxicology.
             

 Research Interest
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Mustafa Naziroglu

Mustafa Naziroglu
Head of Department of Biophysics
Suleyman Demirel University
Turkey

Biography :

I am referee in Biological Trace Element Research (USA), BMC Pharmacology (UK), British Journal of Nutrition (UK), Cell Biochemistry and Function (UK), Cell Biology and Toxicology, Cell Biology International (UK), Chemical Papers (Slovakia), Clinical Chemistry and Laboratory Medicine (France) etc.

 Biography
Research Interest :

Focus on Calcium Signaling and TRP channels, Ion channels and Oxidative stress,Cell Membrane and Oxidative Stress, Free Radical and Antioxidants

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Raghu Tadagavadi

Raghu Tadagavadi
Research Associate
Department of Medicine
Penn State University College of Medicine
Hershey, USA

Biography :

Raghu Tadagavadi is a Junior Faculty in the Department of Medicine at Pennsylvania State University College of Medicine, PA, USA. He received PhD in Biochemistry and Molecular Biology with specialization in Immunotoxicology from Pennsylvania State University College of Medicine, PA. He has obtained graduate training in Veterinary Medicine and a Master degree in Immunology from India. He has received over four years of postdoctoral training in Immunotoxicology and Immunopharmacology at Pennsylvania State University and Emory University. Raghu is a Diplomate of the American Board of Toxicology. He also serves as reviewer and editorial board member for many peer reviewed journals including American Journal of Physiology-Renal Physiology, British Journal of Pharmacology, Cytokine, Clinical Pharmacology and Biopharmaceuticals, Journal of Clinical and Cellular Immunology, Journal of Drug Metabolism and Toxicology, Journal of Clinical Toxicology, Pharmaceutical Sciences, and Plos One. Raghu’s research interests are in the areas of Immunological Toxicology and Pharmacology, and his work focuses on understanding the mechanisms by which the immune system regulates the effects of toxins and pharmaceuticals.

 Biography
Research Interest :

Immunotoxicology, Immunopharmacology, Toxicology

 Research Interest
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Liu Shu

Shu Liu
Postdoctoral Fellow
Thoracic Oncology Laboratory
University of California
USA

Biography :

Shu Liu joined the Thoracic oncology lab in Oct., 2012 as a postdoctoral fellow. Her main research interest here is small molecule drug development. She works on several of exciting drug discovery projects using computational chemistry methods to rationally design, optimize properties of drug candidates and predict ADMET profiles. She also characterizes compounds to understand their activities both in vitro and in vivo. Liu has a Ph.D. in pharmaceutical sciences from College of Pharmacy, University of South Carolina in 2012. She received her Ph.D training from her advisor Dr. Campbell McInness in the drug design and synthesis lab. Liu\s dissertation is entitled design of non-ATP competitive and cell cycle specific CDK inhibitors targeting cyclin binding groove. She also has a B.S. in biological sciences from University of Science and Technology of China in 2005. Her college research work was about transdermal drug delivery.

 Biography
Research Interest :

Small molecule drug development, Computational chemistry, Rational drug designing.

 Research Interest
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Fei Zhao

Fei Zhao
Postdoctoral Associate
Department of Medicine
Duke University
USA

Biography :

Dr. Zhao is a Postdoctoral fellow in Duke University, department of Medicine division of Medical Oncology. He received his doctorate in Pharmacology and Toxicology from the University of Arizona, where he conducted molecular toxicology studies of arsenic mediated malignant transformation and energy metabolism disruption in a human lung epithelial model. He found that chronic exposure of environmental relative concentrations of arsenic can induce the Warburg Effect in human bronchial epithelial cells, which ultimately leads to malignancy. In 2014, Dr. Zhao joined Duke University as a postdoctoral associate to study energy metabolism in melanoma microenvironment. He is the first author or co-author of 11 peer-reviewed articles and a reviewer for Toxicology Sciences and PLOS ONE. Dr. Zhao has won the 2010 and 2011 Superfund Research Program Training Grant, the 2012 Mountain West Society of Toxicology Predoctoral Student Poster Presentation Award 1st Place, the 2013 Society of Toxicology AACT Charles River Best Abstract Award 2nd place, and served as the 2013 Society of Toxicology Arsenic Poster Session Chairperson.

 Biography
Research Interest :

Molecular toxicology studies of arsenic mediated malignant transformation and energy metabolism disruption in a human lung epithelial model.

 Research Interest
 Network
Rahul R. Nahire

Rahul R. Nahire
Castle Medical, LLC
Atlanta GA,
USA

Biography :

Dr. Rahul Nahire is currently working as Lead Toxicologist at Castle Medical, Atlanta GA, USA. He leads the Forensic Urine Toxicology and Clinical Blood and Oral fluid departments at Castle Medical. He is licensed Clinical Lab Director in the State of Georgia and Florida. He is HHS approved NRCC certified Toxicological Chemist. He has PhD in Pharmaceutical Sciences from North dakota State University, Fargo, ND, USA and MS in Pharmaceutical Analysis from National Institute of Pharmaceutical Education and Research, Hyderabad, India. He earned bachelors in Pharmacy from University of Pune, Nashik, India. He holds two US patents and several research articles in high Impact journals.

 Biography
Research Interest :

Clinical and Pharmaceutical Toxicology, Drugs of Abuse testing, forensic drug toxicology, Advanced Drug Delivery, nanotechnology

 Research Interest
 Network
 Acceptance Letter
 
 
 
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