ISSN: 2161-1068

Mycobacterial Diseases
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Editorial Board

David A. Hokey

Editor-in-Chief
David A. Hokey
Department of Immunology
Aeras Global TB Vaccine Foundation
USA
Tel: +240-599-3077

Biography :

Dr. David Hokey is the Director of Immunology at Aeras in Rockville, Maryland.  He received his Ph.D. in Immunology from the University of Pittsburgh in 2005 where he worked primarily on dendritic cell-based tumor vaccines.  He then performed his postdoctoral research under the guidance of Dr. David Weiner at the University of Pennsylvania which focused on DNA vaccines for HIV, cancer, and influenza with an emphasis on primate immunology and polychromatic flow cytometry.  Dr. Hokey’s current work at Aeras involves evaluation of immune responses to TB vaccine candidates in pre-clinical and clinical settings.  His research interests include evaluation of novel vaccine platforms and adjuvants for manipulation of immune responses.

 Biography
Research Interest :

David′s research interests include evaluation of novel vaccine platforms and adjuvants for manipulation of immune responses.

 Research Interest
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Shashank Gupta

Editor-in-Chief
Shashank Gupta

Postdoctoral Research Associate
Johns Hopkins University Baltimore,
USA

Biography :

Dr. Shashank Gupta is working in the area of tuberculosis immunology, signaling and drug development in mouse model of tuberculosis.HIs studies on Mycobacterium tuberculosis helps to understand the underlying mechanisms of host-pathogen interaction with special focus on mycobacterial pathogenesis and the other pathways involved in tuberculosis. His recent studies with efflux pump inhibitors have shown that verapamil can be used to accelerate both the bactericidal and the sterilizing activity of standard tuberculosis treatment.

During his doctoral studies from the Immunology group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi, he investigated the roles of different Voltage Gated calcium channels (VGCC) in regulating protective immunity to mycobacteria in vitro and in vivo. His experiments so far have provided some very interesting and positive results towards development of an alternative therapeutic approach for treatment of drug sensitive as well as drug resistant tuberculosis

 Biography
Research Interest :

Dr.Shashank Gupta current research interests are on determining the plasma levels of different anti-tuberculosis drugs like rifampin and isoniazid when co-administered with the efflux pump inhibitors like verapamil.

His research interest is mainly foccused on Cell Biology, Molecular Biology, Biochemistry, Immunology and Working knowledge of NCBI tools for Bioinformatics Research and software for Biochemistry and Molecular Biology.

 

 Research Interest
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 Acceptance Letter
Haruaki Tomioka

Haruaki Tomioka
Professor and Chairman
Department of Microbiology and Immunology
Shimane University School of Medicine
Japan

Biography :

I am the professor of Department of Microbiology and Immunology,Shimane University School of Medicine, Izumo, Japan. I am acting or have ever acted as a director of Japanese Society for Bacteriology, Japanese Association for Infectious Diseases, and Japanese Society for Tuberculosis, and presently acting as a district leader of these three academic societies in the western part of Japan. I am also an associate editor of three international journals, “Microbiology and Immunology”, “Journal of Infection and Chemotherapy”, and “Chemotherapy Research and Practice”. I am acting or have ever acted as the reviewers for the following journals: J Infect Dis, Infect Immun, Antimicrob Agents Chemother, J Antimicrob Chemother, Int J Antimicrob Agents, Clin Exp Immunol, Future Microbiol, Biochim Biophys Acta, J Med Microbiol, Cell Mol Biol, FEMS Microb Lett, Expert Opin Pharmacol, Expert Opin Invest Drugs, BMC Infect Dis, Lung, J Pharm Pharmacol, etc. In addition, I have ever acted as an executive editor of Curr Pharm Des (IF=5.3) and edited the special issue entitled “Antimycobacterial Drugs: Current Status and Future Prospects”. I have also acted as an editor of the special immunology book entitled “Current Topics on the Profiles of Host Immunological Responses to Mycobacterial Infections”, which was published by Research Signpost. I have published more than 250 scientific articles in peer reviewed international journals and medical book chapters.

 Biography
Research Interest :

Virulence factors of mycobacterial pathogens, mechanisms of macrophage bactericidal activity against mycobacterial organisms, drug targets in Mycobacterium tuberculosis for development of antituberculous drugs, molecular epidemiology of nontuberculous mycobacterial infections
Evaluation of in vitro and in vivo activities of new antimycobacterial agents.

 Research Interest
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Keertan Dheda

Keertan Dheda
Department of Medicine
Division of Pulmonology
University of Cape Town
South Africa
Tel: +27-21-406-6509

Biography :

Keertan Dheda is Associate Professor of Respiratory Medicine and Director of the Lung Infection and Immunity Unit (see website at http://www.lunginstitute.co.za/content/lung_infection.html) within the Division of Pulmonology, Department of Medicine, University of Cape Town.
He is the recipient of several prestigious awards including the 2010 International Union Against Tuberculosis and Lung Disease Scientific Award, the South African MRC Career Development Award, the South African NRF and DST Research Chair Award, and holds several large local and multi-national grants e.g. he is PI of an EU FP7 TBsusgent award of million, and an EDCTP TB-NEAT award of 4.3 million. His main research interests are (i) clinical aspects of MDR & XDR-TB and (ii) the development and validation of field-friendly TB diagnostics. He is also interested in the immunopathogenesis of TB in the human lung and airway-related lung disease. He has established an international collaborative network and a local research program in which 3 Masters and 9 PhD students are currently enrolled.
He has ~75 peer-reviewed publications including first or senior author publications in journals such as the Lancet (IF=31) and AJRCCM (IF=10.8), has a December 2010 ‘H’ index of 18, has several highly cited papers, and his work has been cited 1663 times (as at December 2010). He holds 1 patent related to new TB diagnostic technologies, which is currently being developed as a user-friendly test for extra-pulmonary tuberculosis. He has a keen interest in medical education.
He serves or belongs to several local and international academic societies including Governor for American College of Chest Physicians for the South Africa region, the scientific committee of the TB and Pulmonary Infection group of the American Thoracic Society, and is a fellow of the American College of Chest Physicians.  He serves on the editorial board of the journal PLOS One, and the International Journal of Tuberculosis and Lung Disease.
 

 Biography
Research Interest :

Immunopathogenesis, diagnosis, management and outcomes of lung diseases associated with poverty including TB, HIV and pneumonia.
Specific areas of interest and ongoing work:
Pathogenesis, transmission dynamics, and clinical outcomes of MDR-TB and XDR-TB, development and validation of field-friendly diagnostics for TB, immunopathogenesis of pulmonary TB using cells obtained from the lung.

 Research Interest
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 Acceptance Letter
Jeffrey K. Actor

Jeffrey K. Actor
Professor
Department of Pathology & Laboratory Medicine
University of Texas
USA

Biography :

Dr. Actor, Ph.D., is a tenured full professor in the department of Pathology and Laboratory Medicine at the University of Texas-Houston Medical School, where he is a member of the Academy of Master Educators. His main research interest involves investigating immunological aspects of pathology in models of tuberculosis. Specific interests also include targeted investigation of lactoferrin as an immunomodulatory agent. He serves as course director for Medical Immunology for first year medical students, and is active within the Graduate School of Biomedical Sciences at the University of Texas-Houston Health Science Center.

 Biography
Research Interest :

Dr. Actor’s research interests are directed at understanding the host immune regulation of cytokines and proinflammatory response during infection, specifically investigating lung immunopathology induced during models of tuberculosis in susceptible and resistant mice. It is the hope that understanding the host response to infectious agents will allow development of effective vaccines and therapeutics to combat these diseases. Other goals include development of bovine and human Lactoferrin as a vaccine adjuvant to augment cell mediated immunity, as well as for use as an immunomodulatory agent to control inflammatory processes.

 Research Interest
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Peter Panizzi

Peter Panizzi
Harrison School of Pharmacy
Auburn University
USA

Biography :

Peter Panizzi, Ph.D. is an Assistant Professor in the Harrison School of Pharmacy at Auburn University. He received his doctorate from Vanderbilt University in 2004 and completed at post-doctoral fellowship at the Center for Systems Biology at the Massachusetts General Hospital from 2007-2010. He has co-authored >25 high-impact articles and was awarded a NIH pathway to Independence Grant (K99R00) from NHLBI before coming to Auburn.

 Biography
Research Interest :

Peter Pannizi Current research focus is at the crossroads of molecular imaging, biochemistry and infectious disease research. Our goal is to better understand how certain bacteria are able to cause human disease and in turn we seek to use this knowledge against the microbe to detect specific sites of infections and identify the casual pathogen.

 Research Interest
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Abu Salim Mustafa

Abu Salim Mustafa
Professor
Department of Microbiology
Faculty of Medicine
Kuwait University
Kuwait
Tel: +965-24896505
Read Interview session with Abu Salim Mustafa

Biography :

Abu Salim Mustafa PhD (1979) and FRCPath (1998) and Full Professor (since 1996) at the Faculty of Medicine, Kuwait University, Kuwait. Visiting Professor (Resource Person Program) of American Society for Microbiology/ UNESCO in 2001 and 2004.

Administrative Experience at Kuwait University: Research Coordinator in 1992, Graduate Program Director in 1998, Member of Medical Research Council in 2001 and Director of Research Core Facility in 2012.

Till date, He have published 217 full-length papers and edited 3 books; received 25 national and international research awards,executed 51 funded research grants, and refereed 81 research projects submitted for funding to national and international institutions. Member of the editorial board of two international journals, member of 11 Scientific Societies, supervised 28 graduate thesis, invited speaker in 62 scientific conferences and chaired scientific sessions in 15 conferences. In the recent years, the focus of my research has been molecular biology and immunology of mycobacterial diseases.

 Biography
Research Interest :

Molecular biology and immunology of mycobacterial diseases.

 Research Interest
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Deepak Kaushal

Deepak Kaushal
Associate Professor
Department of Microbiology & Immunology
Tulane University School of Medicine
USA

Biography :

Dr Kaushal is an Associate Professor in the Division of Bacteriology and Parasitology at the Tulane National Research Primate Centre Covington LA with an academic appointment at the Department of Microbiology and Immunology the Tulane University School of Medicine New Orleans LA Since joining TNPRC in 2006 he has been active in the implementation of various aspects of TB research including but not limited to the molecular microbiology studies research aimed at dissecting the role played by various members of the M tuberculosis sigH network including sigE sigB and Rv2745c genes This network is being studied through the use of mutants microarrays cellline and primary macrophages as well as the mouse model His has also developed a rhesus macaque model of TB and of TB/AIDS using natural routes of exposure His lab is leveraging these models to better understand pathogenesis immunopathology latency and reactivation in TB Dr Kaushal is also the Director of the Tulane Institutional DNA Microarray and Expression Core DMEC The core processes spotted 2 color microarrays as well as perform highdimension data analysis from both spotted as well as 1 color Affymetrix microarrays Dr Kaushal work is mainly funded by several institutes and centers at the National Institutes of Health including National Institute of Allergy and Infectious Diseases National Heart Lung and Blood Institute and National Centers for Research Resources He also serves on the editorial board of PLoS ONE.

 Biography
Research Interest :

Kaushal Research Interest includes Tuberculosis, Allergy, Infectious Diseases, and Microarrays.

 Research Interest
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Subramanian Dhandayuthapani

Subramanian Dhandayuthapani
Associate Professor
Department of Microbiology & Immunology
University of Texas Health Science Center
USA

Biography :

Dr Dhandayuthapani is an Associate professor at the Department of Microbiology and Immunology The University of Texas Health Science Center at San Antonio Texas USA DrPani got his PhD from University of Madras India Immediately after his PhD Dr Pani took up a scientist position at the worlds premier institute on leprosy The Central Leprosy Teaching and Research Institute CLTI Chengalpattu in Tamilnadu India to undertake research on the seroepidemiology of leprosy In 1991 he moved to National Institute of Leprosy Research NILR Tokyo Japan as a Science and Technology Agency Fellow where he studied cloning and characterization of Mycobacterium leprae antigenic genes Dr Pani then moved to The University Texas Health Science Center at San Antonio Texas in 1994 as a Postdoctoral Fellow to work on the oxidative stress response of Mycobacterium tuberculosis He later became an Assistant and Associate Professor in the department of Microbiology and Immunology of the same universityDrPanis research focuses mainly on the stress response of mycobacteria He has contributed immensely to the understanding of the pathogenesis of M tuberculosis particularly the role of antioxidants in the intracellular survival of this species and other related mycobacteria.

 Biography
Research Interest :

Dr. Panis research interests are oxidative stress response in mycobacteria, signal transduction and regulation of gene expression in mycobacteria and development of recombinant vaccines to mycobacterial diseases.

 Research Interest
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Gobardhan Das

Gobardhan Das
Professor
Department of Human Health
University of Kwazulu-Natal
South Africa

Biography :

Gobardhandas Ph.D in Institute of Microbial Technology, India. 1997, Thesis on Immunological basis of Susceptibility and Resistance in Animal Models of tuberculosis, A Special Focus on T cell Tolerance , Post Doctoral Training: Prof. Charles A Janeway laboratory at Yale University School of Medicine, Howard Hughes Medical Institute. 19972002, Interest includes Innate like lymphocytes that adjoins innate and adaptive immunity, Senior Scientist in Aventis Pharmaceuticals 20022007, Interest includes Identification and validation of druggable targets for the intervention of allergic and autoimmune diseases.

 Biography
Research Interest :

Gobardhan Research interests include Conventional treatment for tuberculosis involves several antibiotics, a lengthy treatment regimen with expensive drugs, and a high risk of generating drug-resistant forms of the tuberculoid organisms (M. tb). Our laboratory is interested in small molecule directed immunotherapy to promote the generation of immunocytes that provide immunity, and simultaneously inhibit disease-promoting immunocytes. To modulate these immunocytes, we are interested in identifying molecular targets in these cells. Thus, our method has three advantages over conventional antibiotic treatment: expulsion of the harbored tuberculoid organisms; generation of signature protective memory responses; and lack of selection for drug-resistant forms of tuberculosis (MDRs).

 Research Interest
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Vandana Malhotra

Vandana Malhotra
Department of Infectious Diseases and Vaccinology
Arizona State University
USA
Tel: +480-570-8356

Biography :

Dr. Vandana Malhotra is an Assistant Research Scientist in the Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University. For the past 15 years as a graduate student, postdoctoral fellow, and now as an Assistant Research Scientist, Dr. Malhotra has dedicated her scientific career to investigating the genetic and biochemical intricacies that
allow Mycobacterium tuberculosis to cause disease in humans. She completed her Ph.D in 2002 from All India Institute of Medical Sciences, a premier institution in India, where she characterized the devR-devS two-component system of M. tuberculosis, now established as the
key regulator in the transcriptional adaptation of mycobacteria to hypoxia. In 2005, she joined as a post-doctoral fellow in The Biodesign Institute and explored the role(s) of “eukaryotic-like” Ser/Thr protein kinases in M. tuberculosis virulence and host-pathogen interactions. Her studies
on PknK have highlighted the existence of exquisite signaling pathways that regulate mycobacterial growth under stress conditions in culture and during chronic/persistent phase of infection in mice.

 Biography
Research Interest :

Dr. Malhotra’s research interests are focused on the regulation and function of M. tuberculosis signal transduction systems; Two-component systems and Ser/Thr protein kinases, their role(s) in virulence and host-pathogen interactions. How mycobacteria integrate environmental stimuli and
coordinate signaling pathways and regulatory networks to control its growth and metabolism is of significant interest. Her research combines transcriptomic and proteomic approaches to study the molecular mechanisms of these regulatory systems in cell culture and animal models to investigate their functional significance in M. tuberculosis pathogenesis.

 Research Interest
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Diane Ordway

Diane Ordway
Department of Microbiology, Immunology and Pathology
Colorado State University
USA
Tel: +970-491-4117
Fax: +970-491-1815

Biography :

 

Dr. Ordway finished her B.Sc in Microbiology at Colorado State University in 1992. Dr. Ordway received a full doctoral scholarship to attend the London School of Hygiene & Tropical Medicine receiving her Ph.D. in Infectious and Tropical diseases in 2000. Dr. Ordway has the expertise of being an immunologist with 18 years experience using and developing human and animal models of Mycobacterial infection. In addition, Dr. Ordway is one of the leading investigators evaluating whether the newly emerging MDR/XDR-TB strains of extremely high virulence are able to suppress the innate and/or acquired host response compared to other strains under a new innovative grant award. These animal models are used to test vaccines and drugs and provide us with information on the nature of induction of protective immunity.

 Biography
Research Interest :

 

Immunology, Vaccines and Drugs against Pathogenic Mycobacteria Immunology, Vaccines and Drugs against Pathogenic Mycobacteria
Worldwide the rate of drug-sensitive, multi-drug and extensively drug resistant Mycobacterium tuberculosis cases are increasing. The only available vaccine against M. tuberculosis, M. bovis Bacillus Calmette-Guérin (BCG) is unreliable and the use of anti-mycobacterial drugs has only lead to high rates of drug resistance. A particularly dangerous family of clinical strains is the “W-Beijing” family, many of which are highly drug resistant [MDR]. The substantial and relatively rapid transmission of these strains across the world has led people to believe that these particular isolates have some capacity or property to resist, and even subvert, the host immune response. Innovative work in the applicant’s research group has uncovered the possibility that at least some of these isolates can induce Foxp3+ regulatory T cells that interfere with the proper expression of protective immunity in the mouse and guinea pig.

 Research Interest
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Hui-Qi Qu

Hui-Qi Qu
Department of Epidemiology
University of Texas Health Science Center at Houston
USA
Tel: +956-882-7006
Fax: +956-882-5152

Biography :

 

Dr. Hui-Qi Qu’s research interest includes: (1) genetic epidemiology and functional genomics of human common diseases (e.g. obesity, diabetes, and tuberculosis); (2) translational research and biomarker development. He was trained as a clinical doctor of internal medicine in China. From 2003 to 2010, he worked on the genetics of type 1 diabetes and neonatal diabetes by candidate-based approach and genome-wide association study (GWAS) at McGill University, Canada. His study resulted in the identification of novel type 1 diabetes (T1D) loci and a novel gene critical in pancreas development, and the elucidation of molecular mechanisms of diabetes. In 2010, he joined the University of Texas School of Public Health. One of his major research interests is the genetic and environmental risk factors for tuberculosis.

 Biography
Research Interest :

 

Genetic epidemiology, functional genomics, translational research, Diabetes, Obesity, Non-alcoholic fatty liver disease, Tuberculosis.

 Research Interest
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Demelash Biffa Areda

Demelash Biffa Areda
Department of immunobiology
University of Arizona
USA

Biography :

Dr. Demelash Biffa is a post-doctoral research scientist at the University of Arizona, USA. He received his PhD and Master’s degree from Norwegian School of Veterinary Science and Doctor of Veterinary Medicine degree (DVM) from Addis Ababa University, Ethiopia. He also attended postgraduate courses in Israel, Norway, Denmark and Germany. He was a guess researcher at department of bacteriology, Tuberculosis division, Swedish Institute for Infectious Disease Control, Stockholm. His publications in peer reviewed journals include wide range of infectious disease including tuberculosis in animals and humans.Dr Biffa is a member of several prestigious professional associations and societies such as American Association of Immunologist (AAI), American Association for the Advancement of Science (AAAS),American Society for Microbiology (ASM), American Association of Veterinary Immunologist (AAVI), Sigma Xi, The Scientific Research Society, International Society of Infectious Diseases (ISID), and Society for Veterinary Epidemiology and Preventive Medicine (SVEPM). Currently he is serving as editorial board member and reviewer of several peer-reviewed journals. His main area of research interest include epidemiology and immunology of infectious disease, epidemiologic research methods, ecology and Epidemiology of emerging zoonosis and bioterrorism/biological warfare agents,Food safety and veterinary public health.

 Biography
Research Interest :

Molecular microbiology, epidemiologic research methods, molecular epidemiology, infectious disease epidemiology and modeling, ecology and epidemiology of emerging zoonosis and bioterrorism/biological warfare agents, food safety and veterinary public health, immunology of infectious disease.

 Research Interest
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Farahnaz Movahedzadeh

Farahnaz Movahedzadeh
Department of Biological Sciences
Institute for Tuberculosis Research
University of Illinois at Chicago
USA
Tel: +312996-5233

Biography :

Dr Farahnaz Movahedzadeh is Assistant Professor at Institute for Tuberculosis Research ITR College of Pharmacy at University of Illinois at Chicago UIC She earned her PhD from the University College of London UCL and National Institute for Tuberculosis Research NIMR in England Currently she is a Biology Instructor at City College of Chicago and a Research Assistant Professor at UIC She has published many reviewed papers and she was author of 6 book chapters She has teaching experience of more than 10 years She served as the member of National Association of Biology Teachers NABT Association of College and University Biology Educators ACUBE AcidFast Club UK and International union Against Tuberculosis and Lung Disease IUATLD She served as a reviewer of peerreviewed journals in the area of molecular and microbiology and a grant reviewer of NIH She organized the first hybrid conference on “Hybrid learning” at City College of Chicago in 2009 She received awards from different organizations including WHO and SENCER She is also the recipient of grants from ALA CBC and NSF.

 Biography
Research Interest :

Molecular genetics of Mycobacterium tuberculosis, essential genes, latency, virulence, gene regulation and expression, gluconeogenesis, and identification of novel drug targets.

 Research Interest
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Shumaila Nida Muhammad Hanif

Shumaila Nida Muhammad Hanif
Department of Pharmaceutical Sciences
University of Oklahoma
USA
Tel: 405-371-2523
Fax: 405-271-7505

Biography :

Shumaila Nida Muhammad Hanif  born and raised up in Kuwait but originally from Pakistan. She did PhD from, Faculty of Medicine, Kuwait University in medical microbiology in 2007 and currently doing Postdoc at College of Pharmacy, University of Oklahoma, USA. I published 8 full length papers, 47 abstract and one chapter book. I can speak and write different languages like English, Arabic, Urdu and Punjabi.

 Biography
Research Interest :

Molecular diagnosis, Therapy, Vaccination and Infectious diseases.

 Research Interest
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Mario Alberto Flores-Valdez

Mario Alberto Flores-Valdez
Professor
Department of Microbiology
Universidad Nacional Autónoma de México
Mexico
Read Interview session with Mario Alberto Flores-Valdez

Biography :

Mario Alberto Flores-Valdez is a Professor in the Medical and Pharmaceutical Biotechnology Unit, CIATEJ, A.C., Guadalajara, Jalisco, México (2007-present). He is a member of the National System of Researchers (SNI), he was a Stanford University Medical Center postdoctoral fellow (2004-2007), where he received a Dean´s Fellowship Award (2006) to conduct research on Tuberculosis. He worked in UNAM as Research Assistant for Prof. Jaime Mora (2004) and Prof. Emundo Calva (2003). He has received a Ph.D. in Biochemistry from UNAM (1999-2003), a M.Sc. in Molecular Biology and Genetic Engineering from UANL (1996-1999) and a B.Sc. from Universidad de Sonora (1991-1996) in Chemistry and Biology. He has received fellowships from CONACYT for M.Sc. and Ph.D. studies, and grants to study molecular aspects of tuberculosis. He has reviewed articles for several international peer-reviewed journals as well as grants proposals for different CONACYT´s initiatives.

 Biography
Research Interest :

Tuberculosis and other bacterial infectious agents such as Pseudomonas and Staphylococcus. Vaccines and therapies for Tuberculosis. Genomics, Molecular and Cellular Microbiology aspects of bacterial infectious Diseases, particularly Tuberculosis.

 Research Interest
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Delia Goletti

Delia Goletti
Department of Clinical Epidemiology
Translational Research Unit
National Institute for Infectious Diseases
Italy

Biography :

Delia Goletti MD, PhD, Infectious Diseases specialist. In 1992 she joined the Laboratory of Immunoregulation at the National Institutes of Health,Bethesda, USA (chief Dr Fauci) working on the pathogenesis of HIV. In 1996 started working in Italy at the Virology  Laboratory of Istituto Superiore di Sanità (chief Dr. Ensoli) on HIV, SIV, SHIV and evaluating the immune effects of an HIV vaccine in monkeys. In 1999 she joined the National Institute for Infectious Diseases in Rome (scientific chief: Dr Ippolito) as permanent physician employee. At the Health Clinical Department she worked on HIV disease, tuberculosis, hepatitis, respiratory and neurological diseases. In 2006 she joined the Epidemiology Department (chief Dr Girardi) keeping the clinical duties on the Tuberculosis clinic. From 2001 she is responsible of the Translational Research Unit and works on tuberculosis pathogenesis and on immunodiagnostic tests for tuberculosis. She is also a member of the TBNET steering committee.

 Biography
Research Interest :

Tuberculosis (epidemiology, immunology, clinical aspects)
tuberculosis and HIV (epidemiology, immunology, clinical aspects), helminthiasis (epidemiology, immunology, clinical aspects), tuberculosis and IGRA.

 Research Interest
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Horacio Bach

Horacio Bach
Department of Medicine
Division of Infectious Diseases
University of British Columbia
Canada
 

Biography :

Horacio Bach earned his PhD in Molecular Microbiology and Biotechnology from the University of Tel Aviv in 2001, studying the interactions between an esterase and the polysaccharide emulsan. Subsequently, in his first post-doctorate, he joined the laboratory of Prof. David Sherman in Minnesota working on the development of a biochip for generation of novel antibiotic molecules and the roles of P450 proteins from Streptomyces coelicolor. Dr. Bach worked for Taro Pharmaceuticals in Tel Aviv and New York developing novel fermentation technologies and engineering organisms for the production of steroids. In 2004, Dr. Bach joined the laboratory of Prof.  at the Division of Infectious Diseases, Department of Medicine, University of British Columbia in Vancouver, Canada. He worked on the function of tyrosine phosphatases of Mycobacterium tuberculosis and the interactions within the host macrophages. Currently, Dr. Bach holds an Assistant Professor position at the same institution. His current research interests include: signal transduction, mechanism elucidation of virulence factors of Mycobacterium tuberculosis, the link between Mycobacterium paratuberculosis and inflammatory bowel diseases, the design of novel antibodies using antibody engineering, applications of nanotechnology in Medicine, and screening of novel bioactive natural compounds. Prof. Bach is the author of 40 papers, patents, reviews and book chapters.
 

 Biography
Research Interest :

Signal transduction,
Mechanism elucidation of virulence factors of Mycobacterium tuberculosis,
The link between Mycobacterium paratuberculosis and inflammatory bowel diseases,
The design of novel antibodies using antibody engineering,
Applications of nanotechnology in Medicine,
Screening of novel bioactive natural compounds

 

 Research Interest
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Diego Soler-Tovar

Diego Soler-Tovar
Department of Agricultural Sciences
Epidemioloy and Public Health Group
Universidad de La Salle Bogotá Colombia
Colombia
Tel: +57-316-3548919

Biography :

Im Diego Soler-Tovar, live and work in Colombia, I am currently Assistant Professor at the Faculty of Agricultural Sciences and Research Group of Epidemiology and Public Health at the Universidad de La Salle; also am the General Director of the Asociación de Veterinarios de Vida Silvestre (VVS), Executive Secretary of the Asociación Colombiana de Ornitología (ACO) and Regular Member of the Wildlife Disease Association (WDA). I am a veterinarian with a Masters in Animal Health on the line of Microbiology and Epidemiology. I have conducted research (individually, with other colleagues or professionals or students), reported results through oral or posters at conferences nationally and internationally and published on topics such as ethics and biodiversity, biosafety, events of interest in public health, infectious diseases such as mycobacteriosis, avian influenza, West Nile virus, among others, in different vertebrate species, fragmentation of habitats of endangered species and their possible relationship to disease or pathogens, animal-human interfaces, medical, management and rehabilitation wildlife.

 Biography
Research Interest :

Conservation Medicine, Human/Animal Interface, Ecology of Wildlife Diseases, Public Health and Epidemiology.

 Research Interest
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Fekadu Abebe

Fekadu Abebe
Department of Community Medicine
University of Oslo
Norway

Biography :

Dr. Fekadu Abebe is a scientist at the Faculty of Medicine, University of Oslo, Norway. He obtained his PhD in immunology from the Department of Immunology and Transfusion Medicine, Ulleval University Hopsital, University of Oslo. After completion of his PhD training, he was employed as a postdoctoral fellow at the Faculty of Medicine, University of Oslo. He received his BSC (Biology) and MSc (Parasitology) from the Faculty of Natural Sciences, Addis Ababa University, Ethiopia. He has been a researcher and lecturer at Aklilu Lemma Institute of Pathobiology, Addis Ababa University for many years. Dr. Abebe`s work include plant molluscicide, epidemiology and immunology of schistosomiasis, with special emphasis on specific antibody responses and puberty-related hormones on Schistosoma mansoni worm load. Dr. Abebe`s group was the first to show the influence of dehydroepiandrosterone- sulphate (DHEAS) on Schistosoma mansoni worm load in humans. Currently, Dr. Abebe is engaged in tuberculosis research, including tuberculosis epidemiology, immunology and molecular genetics. He is leading major projects that deal with molecular genetics, epidemiology, immunodiagnosis, protective immune markers during Mycobacterium tuberculosis in human population. Dr. Abebe`s publications include cytokine profile during latent and progress tuberculosis; the Beijing genotype of Mycobacterium tuberculosis and the protective efficacy of BCG; serodiagnosis of tuberculosis; and the protective role antibody responses during Mycobacterium tuberculosis infection. Dr. Abebe`s main research interest is immunology of tuberculosis, including cell-mediated and antibody responses; immunodiagnosis, and vaccine immunology.

 Biography
Research Interest :

Dr. Abebe `s research interest include immune responses to infectious diseases, immunodiagnosis, and vaccine immunology, with especial emphasis on tuberculosis.

 Research Interest
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Clovice Kankya

Clovice Kankya
Department of Veterinary Public Health
Makerere University
Uganda
Tel: +256-772-545999

Biography :

Dr.CloviceKankya is set to receive his PhD in Epidemiology and Public health from the Norwegian School of Veterinary Science (NVH) in Dec 2011.  Currently, he is working as Lecturer in Makerere University Kampala (MAK) Uganda.
He is serving as an editorial member of several reputed journals like Journal of Epidemiology and Public health. He has authored in the area of mycobacterial infections in the pastoral ecosystems of Uganda in BMC and tropical animal health and production research articles and AIDS book. He is a member of Uganda Veterinary Association (UVA).
 

 Biography
Research Interest :

Zoonotic infections (emerging and re-emerging zoonoses) and Rural Development. I would prefer to build a “hub” for nontuberculous mycobacterial(NTM) infection research in Uganda and the great lakes region.

 Research Interest
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Marcus Vinicius Nora De Souza

Marcus Vinicius Nora De Souza
Department of Medicinal Chemistry
Fiocruz Research Institue
Brazil

Biography :

Marcus V. N. de Souza was awarded his Ph. D. degree in organic synthesis from University Paris XI, Paris - France in 1999 under the supervision of Prof. Robert H. Dodd. He then worked with Prof. Robert H. Holton as postdoctoral research in medicinal chemistry at Florida State University - USA. Afterwards, he moved to University of Juiz de Fora - MG, Brazil where he worked as a visiting professor. At present, he was selected for a position at Fiocruz Research Institue, Rio de Janeiro - Brazil where he has a research group in medicinal chemistry synthesis department. His main interest in research is centered on neglected disease (Tuberculosis and Malaria) and synthetic methodologies.

 Biography
Research Interest :

Far-Manguinhos FioCruz - RJ, Genzymes collaboration with Fiocruz, Antimalarial activity of 4-(5-trifluormethyl-1H-pirazol-1-yl)-chloroquine analogues, Synthesis of carbohydrates compounds, Preparation of heptoses from quinic acid, Synthetic Applications of 3-Amino-5-piperidein-2-ones: Synthesis of Methionine-derived Peptidomimetics, medicinal chemistry and Research in Tuberculosis.

 Research Interest
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Amr Mohamed

Amr Mohamed
Associate Professor of Molecular Diagnostics
Department of  Animal Medicine
Assiut University
Egypt

Biography :

 Dr. Amr M. Mohamed has received his PhD in University of Nebraska Medical Center (UNMC) during the period of 2004. Currently, he is working as Associate Professor of Molecular Diagnostics of Infectious Diseases in Umm Al-Qura University, Saudi Arabia. In addition, he has a permanent position of Associate professor at Faculty of Veterinary Medicine, Assiut University, Egypt. He has successfully completed his Administrative responsibilities as Vice Chair of Laboratory Medicine Dept., Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia. He has authored 20 research articles. He/she is a member of American Society of Microbiology, International Society of Camelids Research and Development (ISCRD), International Veterinary Information Services (IVIS), Egyptian Society for Cattle Diseases, Reviewer in the “Veterinary Journal” (British Veterinary Journal), Reviewer in the "Journal of Veterinary Diagnostic Investigation".

 Biography
Research Interest :

Molecular diagnosis of Mycobacterial diseases, molecular diagnosis of infectious diseases, molecular approaches for development of subunit vaccines against tuberculosis, tularemia and blood parasites, application of Molecular diagnostic techniques for studying of drug resistant tuberculosis.

 Research Interest
 Network
Yun Sang Cho

Yun Sang Cho
Department of Animal and Plant Health
Quarantine and Inspection Agency (QIA)
Republic of Korea
Tel: +82-31-467-1952
Fax: +82-31-467-1938

Biography :
 Biography
Research Interest :
 Research Interest
 Network
 Acceptance Letter
Sayera Banu

Sayera Banu
Department of Microbiology
Tuberculosis Laboratory
Bangladesh
Tel: +880-2-8860523-32
Fax: +880-2-8812529

Biography :

Dr. Sayera Banu joined ICDDR,B in 1991 and is currently a Scientist in the Tuberculosis Laboratory under Laboratory Sciences Division. She has completed her MBBS in Medical Science from the University of Dhaka, Bangladesh in 1989; then she received a M.S in Microbiology from the University of Tsukuba, Japan in 1997 and Ph.D. Microbiology from the University of Dhaka, Bangladesh in 2003. She conducted post graduate training in Mycobacteriology at the Institut Pasteur, Paris from 1998-1999. She has successfully completed several projects over the last ten years both as principal investigator and co-investigator. In some of the projects she worked as a major foreign investigator. She has the expertise of leading any project involving epidemiology, microbiology, immunology and molecular biology of TB. She has the record of successful and productive research projects in the field of TB and leprosy.

 Biography
Research Interest :

Mycobacteriology (Tuberculosis and Leprosy).

 Research Interest
 Network
Mochammad Hatta

Mochammad Hatta
Department of Molecular Biology & Immunology
Hasanuddin University
Indonesia

Biography :

Prof. Hatta is a professor on Molecular Biology and Immunology for Infectious Diseases from Medical  Faculty of Hasanuddin University, Makassar, Indonesia. Prof Hatta got his MD degree from Hasanuddin University, Indonesia  in 1983, his PhD in Molecular Microbiology and Immunology from Toyama Medical and Pharmaceutical University, Japan in 1992. He is Consultant of Clinical Microbiologist since 2001. Prof. Hatta is know for his research in Molecular Biology and Immunology aspects of Mycobacteria, Salmonella typhi,  leptospira; Development new simple diagnostic test for typhoid fever, leprosy, leptospirosis, and brucellosis.
Development of recombinant DNA BCG vaccine; Molecular epidemiology study of leprosy and typhoid fever; Development and evaluation of effectivity Salmonella typhi vaccine; Molecular genetic study of leprosy and application of chemoprophylaxis for leprosy; Genome snp analysis for S. typhi in Indonesia and novel new flagellin gene Indz66; Operational research of tuberculosis in isolated islands of Indonesia. He develop the simple diagnostic tools for typhoid fever; chemoprophylaxis of leprosy and new flagellin gene Indz66 of S. Typhi.  
He former Head Department of Microbiology, Hasanuddin University and Editor member African Biotechnology Journal (ABJ),  Editor board of Education Research and Reviews Journal, Peer reviewer Journal Clinical Infectious Diseases (CID), USA, Peer reviewer Monitoring Biomedical Science. New York, USA.

 Biography
Research Interest :

Molecular Biology and Immunology aspects of Mycobacteria, Salmonella typhi, leptospira. Development new simple diagnostic test for typhoid fever, leprosy, leptospirosis, and brucellosis. Development of recombinant DNA BCG vaccine. Molecular epidemiology study of leprosy and typhoid fever. Development and evaluation of effectivity Salmonella typhi vaccine. Molecular genetic study of leprosy and application of chemoprophylaxis for leprosy. Genome snp analysis for S. typhi in Indonesia and novel new flagellin gene Indz66. Operational research of tuberculosis in isolated islands of Indonesia. Develop the simple diagnostic tools for typhoid fever; chemoprophylaxis of leprosy and new flagellin gene Indz66 of S. Typhi.

 Research Interest
 Network
Ikonomopoulos John

Ikonomopoulos John
Faculty of Animal Science and Aquaculture
Agricultural University of Athens
Greece
Tel: +30-694-5484027
Fax: +30-210-5294388

Biography :

Assistant Professor Ikonomopoulos J is a Veterinary Doctor (Aristotelian University of Athens) with specialty (MSc Royal Veterinary College University of London; PhD School of Veterinary Medicine Aristotelian University of Athens) currently employed by the Agricultural University of Athens, School of Animal Science and Aquaculture, at the level of Assistant Professor of Animal Health with emphasis on Microbial Diseases.   
His work refers mainly to molecular detection of mycobacterial pathogens and the investigation of the pathogenesis of the diseases they cause to humans and animals. This work has produced 45 publications in peer reviewed journals, 395 hetero-citations, 42 announcements in scientific congresses that were awarded in 7 cases, 1 granted International Patent and 3 European Patent Applications. Assist. Professor Ikonomopoulos has coordinated several international competitive research projects and is serving as an editorial member of The Open Biomarkers Journal and the Journal of Infectious Diseases and Immunity.

 Biography
Research Interest :

Microbial detection using Molecular Biology and Nanotechnology, Genetic polymorphisms associated with disease predisposition to infections induced by intracellular bacteria, Pathogenesis of mycobacterial infections, Diagnostic support for brucellosis and leishmaniasis.

 Research Interest
 Network
Adrian Muwonge

Adrian Muwonge
Department of Food Safety and Infection Biology
Centre for Epidemiology and Biostatistics
Norwegian School of Veterinary Science
Norway
Tel: +46390663

Biography :

Dr. Adrian is currently pursuing a PhD in Epidemiology and Public health at the Norwegian School of Veterinary Science (NVH) in collaboration with Norwegian veterinary institute, public health instituted in Oslo and the department of public health at the School of veterinary medicine Makerere University.  He holds a Masters of food safety (MSF) from NVH and Bachelors of veterinary medicine from Makerere University, Kampala Uganda.
He has authored in the area of mycobacterial infections in the Uganda, and yet to in Ethiopia and Zambia in Bio Med Central (BMC) series, Tropical animal health and production research articles and a book chapter in Global view of HIV Infection book. He is a member of Nordic society for veterinary epidemiology (NOSOVE).  Dr. Adrian  is also  serving as the president of the Uganda Norwegian institutions alumni (UNIA)

 Biography
Research Interest :

Epidemiology of infectious zoonotic diseases with special emphasis on Tuberculosis and infections due to Non-tuberculous mycobacteria in HIV/AIDS patients, the role played by farm animals in disseminating infections a case in point: the role played by swine in disseminating mycobacterial infections to humans, epidemiology of food borne infections  and population dynamics with regards to susceptible groups and genetic predispositions, neglected zoonoses and Public health, Socioeconomics of zoonotic infections at the human-Environment-Livestock /Wildlife interface (HELI), certification of food products, food security, renewable energy.

 Research Interest
 Network
Bjorg Marit Andersen

Bjorg Marit Andersen
Professor in Hygiene and Infection Control
Department of Hospital Infections
Oslo University Hospital
Norway

Biography :

Professor in Infection Control and Hygiene, Oslo University Hospital and Diakonova University College, Oslo, Norway. Infection control doctor and specialist in medical microbiology. Amanuensis in Infectious diseases, Ullevål University Hospital, 1975-79, specialist in medical microbiology 1984, Ph.D in 1989 (Medical microbiology/Infectious diseases). Department of Medical microbiology, Tromsø University Hospital 1986 -1988, Head of Department of Medical microbiology, Tromsø University Hospital 1988-1994, Medical Leadership Education, 1990-1992, Guest researcher at the Meningitis and Special Pathogens Laboratory Section, Centers for Disease Control and Prevention (CDC), Atlanta, USA. Atlanta 1992-1993, Head of Department of Hospital Infections, Ullevål University Hospital, Oslo 1994- 2011.Guest visitor/researcher at Minnesota Department of Health and the Mayo Clinic, Minnesota, USA 2002.Professor in Infection Control and Hygiene at Diakonova University College and Oslo University Hospital-Ullevål since 2004. More than 300 publications within the field of medical microbiology/infectious diseases/hospital infection control, including more than 100 original works. In addition several review articles, abstracts, books, etc.

 Biography
Research Interest :
 Research Interest
 Network
Mohammad Reza Ardalan

Mohammad Reza Ardalan
Associate Professor
Department of Nephrology
Tabriz University of Medical Sciences
Iran
Tel: +98-914-1168518
Fax: +98-411-3344280

Biography :

He is working as an Associate Professor, Department of Medicine, Nephrology division, Imam Hospital, Tabriz University of Medical Sciences.

 

 Biography
Research Interest :

Transplant immunology and tolerance, thrombotic microangiopathy, viral infections and kidney disease, clinical nephrology, Glomerulonephritis, nephropathology, peritoneal dialysis, history of Medicine, anatomy.

 Research Interest
 Network
Amer Hayat Khan

Amer Hayat Khan
Department of Clinical Pharmacy
Universiti Sains Malaysia
Malaysia
Tel: 0060-14-9227580

Biography :

I successfully completed my PhD in Clinical Pharmacy from Universiti Sains Malaysia, Malaysia in 2010. Currently I am Senior Lecturer in Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia. During my PhD, I was working on communicable diseases, specifically on Tuberculosis and co-morbidities, in Malaysia. I have keen to pursue my career in teaching and in research. My main focus in research is Infectious diseases where I have many research articles. And currently I am supervising Master and PhD researchers. I am the author of one Book.

 Biography
Research Interest :

Infectious diseases.

 Research Interest
 Network
Cemalettin Bekpen

Cemalettin Bekpen
Department of Molecular Biology and Genetics
Bogazici University
Turkey
Tel: +90-2123594676

Biography :

Completing my Ph.D. degree under the direction of Prof. Dr. Jonathan C. Howard, one of the pioneers in immunogenetics, has given me a great perspective about cell genetics and innate immunity. I worked on the comparative genomics and function of the IRG gene family which is involved in cell-autonomous immunity in mice. To do my post-doctoral studies, I moved to Prof. Evan Eichler’s Lab., at the Genome Sciences in University of Washington, Seattle, USA in the beginning of September 2006. During my post doctoral studies, I have studied the functional characterizations of the genes embedded within human core segmental duplication regions. Currently. I am working in Swiss Institute of Allergy and Asthma Research (SIAF) as research associate to study whether any of the human specific gene families involve in immune response in human. In the mean time, I am establishing my research group in the  Department of Molecular Biology and Genetics, Bogazici university, Istanbul Turkey. 

 Biography
Research Interest :

Most genes in the human genome are found within the orthologous genomic segments. However, small subsets of gene families (n=9) such as morpheus, and LRRc37, which have been subjected to a burst of segmental duplications, are found within the paralogous genomic regions. These gene families are frequently organized around “core” duplicons that has enriched gene expression in human, some of which are evolving under positive selection. These genes are different from classical gene families and share some common characteristics. They are embedded within the core duplicons, and have not been properly studied or annotated because orthologs do not exist in out-group species, and are embedded in complex regions where 1:1 sequence alignments have been problematic. Most of these gene families show different expression pattern when compared to ancestral gene locus. Recent studies indicate that these genes are one of the major contributors to genetic variations between human individuals. Therefore, we propose that these genes represent novel gene families that confer selective advantage in human evolution and are important for human specific diseases. We aim to identify and functionally characterize newly evolved genes that are embedded within human core duplicons. Specifically, we are searching whether any of these human specific gene families involve in immune response in human.

 Research Interest
 Network
Aylin Turel Ermertcan

Aylin Turel Ermertcan
Department of Dermatology
Faculty of Medicine
Celal Bayar University
Turkey

Biography :

I was born in 1973 in Eskişehir-Turkey. I graduated from Medical Faculty of Hacettepe University-Ankara in 1996. I completed my speciality (dermatology) in the year of 2000.

 Biography
Research Interest :

Pscychodermatology, Infectious dermatoses, Skin cancer, Psoriasis and acne.

 Research Interest
 Network
 Acceptance Letter
P. M. S. Chauhan

P. M. S. Chauhan
Division of Medicinal and Process Chemistry
Indian Society of Chemists and Biologists(ISCB)
Central Drug Research Institute (CDRI)
India
Tel: + 91-9415106859 (M)
Fax: +91-0522-2623405

Biography :

Prof.(Dr.) P.M.S.Chauhan  has received his PhD   from Agra University , Agra, India, in the year 1984. Currently, he is working as Professor and Scientist-F (Deputy Director) in Central Drug Research Institute, Lucknow, India. He is serving as an editorial member of several reputed journals like Future Medicinal Chemistry (future science group) etc. He has authored 95. Research articles/books. He is a member of Royal Society of Chemistry ,Indian Society of Chemists and Biologists(General Secretary), Association of pharmaceutical professionals. He has honored as award for outstanding contributions in Medicinal chemistry and international scientific collaboration  (Scientific Partnership Foundation,Moscow,Russia,2005), Rashtriya Gaurav Award, 2010, Indian International Friendship Society, New Delhi, Fellow of Royal Society Chemistry( FRSC) etc.

 Biography
Research Interest :

Last 26years,his group was involved in design and synthesis of bio active heterocycles as Antitubercular, Antimalarial, Antileishmanial and Anticancer agents.

 Research Interest
 Network
Keshar Mohanty

Keshar Mohanty
Department of Immunology
National JALMA Institute (ICMR)
India

Biography :

Educational Qualifications:
      Ph.D (Zoology)
      M.Sc (Life sciences)

Discipline:
      Immunology

Fields of specialization:
      Mycobacterial Genetics
      Immunology of Filariasis
      Immunology of Leprosy

Awards:
      JRF (ICMR)
      SRF (ICMR)
      JRF AFTER QUALIFYING CSIR-UGC(NET)-1987
      SRF (CSIR)
      R.A. (I.I.SC., BANGALORE)
      RA (ILS, BHUBANESWAR)
 

 Biography
Research Interest :

1.Understanding the mechanism of immunopathogenesis in leprosy and Tuberculosis
•Studies on host susceptibility and association of gene polymorphism of receptors (TLRs and NOD 2), chemokines(CCL2), NOS 2 genes with tuberculosis and leprosy.
•Exploration of plasma soluble receptors (sTLR2) as biomarkers of disease 2. Understanding immunopathogenesis of leprosy reactions
• Immune response to various stress proteins of M leprae, nitric oxide metabolism during reactions and their role as immunological markers for reactions
3. Understanding local immunity in leprosy lesions

• Local antibody synthesis, cytokine secretion and characterization of lesional cells by immunohistology
• Analysis of NOD 2 localized in lesional tissue of leprosy patients. progression(Tuberculosis)

 Research Interest
 Network
Raman Deep Singh

Raman Deep Singh
Department of Biochemistry
Translational Health Science and Technology Institute
Vaccine and Infectious Disease Research Centre
India

Biography :

The doctoral work carried out at Department of Biochemistry, University of Delhi South Campus focused on analysis and characterization of genes associated with M. tuberculosis pathogenesis. We were the first research group to experimentally prove that mycobacterial protein tyrosine phosphatases are indeed involved in pathogenesis of mycobacteria. I was also involved in studies evaluating the protective efficacy of recombinant BCG, DNA vaccines either alone or in a prime boost approach in guinea pigs model of tuberculosis, After obtaining my Ph.D., I moved to Tuberculosis Research Section at National Institutes of Health, MD. During my post-doctoral tenure, we collaborated extensively with the Novartis Institute for Tropical Diseases, Singapore to understand the mechanism of action of bicyclic nitroimidazole, a drug currently in phase2a clinical trials. We have shown that activation of PA-824 by Deazafllavin Dependent Nitroreductase (Ddn) resulted in formation of 3 major metabolites; the major one is corresponding des-nitro imidazole. Des-nitro metabolite formation resulted in generation of reactive nitrogen species, including nitric oxide, which are the major effectors of the anaerobic activity of these compounds. We have also built a QSAR model for activation of bicyclic nitroimidazoles by a Ddn, which should facilitate our collaborative on-going effort to synthesize a more potent bicyclic nitroimidazoles. Another aspect of research at NIH was to understand mechanism of persistence of M. tuberculosis.

 Biography
Research Interest :

Raman Deep’s Research interest includes Host-pathogen interactions using Mycobacterium as a model, Mechanisms of Virulence and Persistence of M. Tuberculosis, Identifying novel drugs against mycobacteria in a collaborative effort with other groups/industry and there by identifying novel drug targets for chemotherapy, Design better vaccines against mycobacteria.

 Research Interest
 Network
Rabia Hussain

Rabia Hussain
Department of Pathology and Microbiology
The Aga Khan University
Pakistan

Biography :

Professor Rabia Hussain holds a PhD in Bacteriology and Immunology from University of Western Ontario and an MRC and  FRC (Path) from the Royal College of Pathologist, UK.   She did her Fellowship training at the Johns Hopkins University, USA, where her research area was the structural and genetics basis of allergy.  Dr Hussain was a Senior Staff Fellow at National Institutes of Health. She won the Berson-Yallow award working at NIH for developing a sensitive radio-immunoassay to assess parasite specific allergic responses. Her seminal studies into natural immuno-regulation of allergic responses in parasitic diseases provided fundamental insights into the control of allergic reactivity.  Dr Hussain has been at The Aga Khan University since 1986, where she holds an Endowed Professorship and carries the title of Distinguished National Professor. She has published extensively in the area of Immune regulation in mycobacterial diseases such as leprosy and tuberculosis.

 Biography
Research Interest :

Professor Rabia Hussain started her academic career in Karachi, Pakistan, with a Masters degree in Microbiology (1967) subsequently proceeding to Canada for post graduation (PhD; 1973) and Post doctoral training Johns Hopkins University and National Institutes of Health in USA. Her research focus was the fundamental understanding of immune-regulation in relation to disease outcome in infectious diseases. In her early career she won the Berson-Yallow award for developing a sensitive assay to assess parasite specific allergic responses. Her seminal studies provided fundamental insights into the control of allergic reactivity and now form the basis of monitoring desensitization regimens in allergic disease. In 1985, Dr Hussain returned to Karachi, Pakistan to join The Aga Khan University and set up a State-of-the-Art Immunology Research Laboratory in the field of infectious diseases, Here her focus shifted to Immuno- regulation in leprosy and tuberculosis.  She has published widely on the role of B and T cells in immunopathogenesis of mycobacterial diseases and recently she has been looking at immune biomarkers associated with disease severity and disease progression in tuberculosis.

 Research Interest
 Network
Alfred Allan Duker

Alfred Allan Duker
Department of Geomatic Engineering
Kwame Nkrumah University of Science and Technology
Ghana
 

Biography :

Alfred Allan Duker is a senior Lecturer in the Department of Geomatic Engineering of the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana. He received his doctorate degree (in the environmental implications of Mycobacterium ulcerans (MU) infection) from the ITC/Wageningen University in the Netherlands. His research is in the impact of the environment on human health. He is known for his research in the contribution of trace elements in MU infection. He has reviewed articles in several international peer-reviewed journals, and a member of the editorial board of the Journal of Trace Elements in Medicine and Biology.

 Biography
Research Interest :

His research interest is mainly in the impact of trace elements in Mycobacterium ulcerans infection and other human diseases.

 Research Interest
 Network
Dr. Amani Alnimr

Dr. Amani Alnimr  
College of Medicine
University of Dammam
Tel: +9668966666 (2111 or 3054)
Saudi Arabia

 

Biography :
 Biography
Research Interest :

Tuberculosis

 Research Interest
 Network
Leonard Amaral

Leonard Amaral
Institute of Hygiene & Tropical Medicine of Lisbon
Universidade Nova de Lisboa
Portugal



Biography :

Leonard Amaral, M.D., Ph.D., is a Professor in Institute of Hygiene & Tropical Medicine of Lisbon at Universidade Nova de Lisboa. He received his doctorate and completed his post-doctoral fellowship from City University of New York in 1968.

 Biography
Research Interest :

His research interest mainly focuses on development of methods for rapid evaluation of over‐expressed efflux pumps of multi‐drug resistant bacteria and cancer cells, development of drugs for therapy of multi‐drug resistant tuberculosis infections and development of drugs for therapy of multi‐drug resistant cancers.

 Research Interest
 Network
Gloria Maria Molina-Salinas

Gloria M. Molina-Salinas
Researcher Associate
Unidad de Investigación Médica Yucatán
México
Tel: +52-999-1880738
Read Interview session with Gloria María Molina-Salinas

Biography :

Gloria M. Molina-Salinas is Researcher Associate Level D at Instituto Mexicano del Seguro Social, Mexico. She has completed Master in Science, Analytical Chemistry, UANL and Bachelors at Clinical Chemistry, Medicine Faculty, Universidad Autónoma de Nuevo León (UANL), Monterrey México

 Biography
Research Interest :

Bioguided isolation of natural products with pharmacological activity (mainly antituberculosis) . Search and development of anti-tuberculosis drugs with activity on TB MDR and XDR . Epidemiology and Molecular Biology of Tuberculosis. Development and validation of bioanalytical methods to quantify drugs and their metabolites in biological samples.

 Research Interest
 Network
Gonzalo Ocejo-Vinyals J

Gonzalo Ocejo-Vinyals J
PhD Servicio de Inmunología,
Spain
Read Interview session with Gonzalo Ocejo-Vinyals J

Biography :

Gonzalo Ocejo-Vinyals is currently pursuing my PhD in Molecular Biology and Immunology.He got his specialist degree in Immunology in 1994 at the Hospital Universitario Marqués de Valdecilla (Santander, Spain).After having worked for 10 years as a Field Specialist in several companies dedicated to Biotechnology.

 Biography
Research Interest :

Immunogenetic of Pulmonary tuberculosis mainly focused in genetic variations related with susceptibility or resistence to Mtb infection. Primary Immunodeficiencies (diagnosis and treatment) Histocompatibility (HLA & disease / KIR genes & disease)

 Research Interest
 Network
 Acceptance Letter
Thean-Hock Tang

Thean-Hock Tang
Associate Proffessor
Universiti Sains Malaysia
Malaysia

Biography :

Tang Thean Hock obtained his doctorate degree in the filed of RNomic from the University of Muenster, Germany under the guidance of Prof. Juergen Brosius.

 Biography
Research Interest :

His research group focuses on Experimental RNomic identification and functional characterization of non-protein-coding RNA (npcRNA) from infectious agents.He is also interested in the development of molecular diagnostic method based on new npcRNA gene markers and RNA technology i. e. SELEX technology for the generation of aptamer.

 Research Interest
 Network
Supriya Pokkali


supriya pokkali
Division of Pediatrics and Center for Tuberculosis Research
John Hopkins University
USA

Biography :

Dr. Supriya Pokkali finds her interest in immunology and infectious diseases with special emphasis on Tuberculosis. She successfully qualified the National Entrance Test (NET) conducted by Indian Council of Medical Research (ICMR) and joined National Institute for Research in Tuberculosis (formerly Tuberculosis Research Center) for her doctoral studies (2004-2009). During her PhD, she predominately worked in clinical immunology lab where she had extensive access to human subjects with pulmonary and extra-pulmonary (TB pleuritis) form of the disease. Thus, she focused on • Role of chemokines and their receptors in inducing immune cell migration to the infection foci (published in various international peer reviewed journals). • Highlighted that IP-10 is a good diagnostic marker for diagnosing extra-pulmonary tuberculosis such as tuberculous pleurisy (published in DMID 2008). Currently, she works at Division of Pediatrics and Center for Tuberculosis Research at Johns Hopkins University. She is extensively involved in development of pre-clinical animal models to understand the molecular basis of human TB pathogenesis: Host-pathogen interactions. Since 2014, she is also a fellow at Center for infection and inflammation imaging (Ci3R) where she is a part of the team involved in developing bacterial specific tracer for easy diagnosis of infection using imaging modalities.

 Biography
Research Interest :

1) Development of pre-clinical animal models to understand the molecular basis of human TB pathogenesis: Host-pathogen interactions
2) Neuro-immunological effect of tryptophan metabolites on Microglial and astrocyte activation during CNS TB pathogenesis.
3) Non-communicable diseases and susceptibility to tuberculosis.
4) Host-directed therapeutics.

 Research Interest
 Network
Anand Kumar Maurya

Guest-Editor
Anand Kumar Maurya
Senior Resident
Department of Microbiology
AIIMS
Jodhpur, Rajasthan
India

Biography :

Dr. ANAND KUMAR MAURYA is working as Senior Resident in the Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, giving routine laboratory diagnosis of (Mycobacteriology, Bacteriology and Parasitology) and Lecture/Practical Demonstration of M.B.B.S and B.Sc Nursing students. He has been awarded with many awards and grants such as Keystone Global Heath Travel Award from Bill and Melinda Gates Foundation Global Health Travel Award, Silverthorne, Colorado, USA for Keystone Symposium, ESM Travel Grant from European Society of Mycobacteriology, Germany for 34th Annual Congress of European Society of Mycobacteriology, Wellcome Trust Bursary award from Wellcome Trust, UK for Wellcome Trust Advance Course “Genomic and Clinical Microbiology” Cambridge, UK and many other.

 Biography
Research Interest :

His research interests include Phylogenetic and phylogeografic analysis of multi-drug resistant tuberculosis, Nontuberculous Mycobacteria infections among pulmonary tuberculosis and extra-pulmonary tuberculosis cases, Rapid molecular diagnosis of MDR / XDR-TB and Clinical mycobacteriology.

 Research Interest
 Network
 Acceptance Letter
Selva Kumar Subbian

Guest-Editor
Selva Kumar Subbian
Assistant Professor
Public Health Research Institute (PHRI)
Rutgers Biomedical and Health Sciences
Newark, New Jersey
USA

Biography :

Over the past several years, my research is focused towards understanding the host immunological determinants that are responsible for the progression of Mycobacterium tuberculosis (Mtb) infection to active TB disease versus control of infection and establishment of latency. I am also exploring the possibilities of adjunctive immune modulation as an intervention to improve current TB treatment with antibiotics. For these studies, I have been using our well established rabbit models of pulmonary Mtb infection, in which the outcome following infection is dependent on the nature of Mtb strain used for infection. Using cutting edge molecular technologies, such as microarray and bioinformatics approaches, I have identified several gene networks and pathways that are significantly differentially regulated in the rabbit lungs, that can be responsible for the differential outcome following pulmonary infection by Mtb strains HN878 (active TB) and CDC1551 (latency). We are the first to report the molecular determinants of protective (latent TB) versus permissive (active TB) host response to Mtb infection in rabbit lungs as early as 3 hours post infection. In the rabbit model of active TB, we have shown a significant improvement in bacterial clearance and lung pathology when the animals were treated with a combination of anti-TB drugs and small molecule inhibitors of phosphodiesterase-4 (PDE4i), compared to treatment with antibiotics alone. For more than 15 years, I have been working with pathogenic mycobacterial strains in Biosafety Level-3 facilities and with several small animal models of TB, including mice, guinea pigs and rabbits, for more than 7 years. I have been working extensively with various primary cells and immortal cell-lines of rabbit, murine, fish and human origin.

 Biography
Research Interest :

Areas of Specialization: • Mycobacterial Pathogenesis (cellular, molecular, biochemical and immunological aspects) • Transcriptional Regulation • Host-Pathogen Interactions in bacterial infections/diseases • Host Immune Response • Animal Models of Infectious Diseases • Genome-wide Transcriptional Analysis and Systems Biology • Biomarker Discovery • Translational Research • Drug Target Development

 Research Interest
 Network
 Acceptance Letter
Gerd Pluschke

Guest-Editor
Gerd Pluschke
Head of Department
Medical Parasitology and Infection Biology
Swiss Tropical and Public Health Institute
Basel
Switzerland

Biography :

Prof. Gerd Pluschke is the head of Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland. He also holds a profile of Professor in Infection biology and immunology. His basic research is in infection biology focusing on host–pathogen interactions, molecular epidemiology, immunology and vaccine design and research activities on Buruli ulcer in the fields of molecular epidemiology, transmission, immunology, treatment and diagnosis.

 Biography
Research Interest :

Research activities focussing on the immunology, host –pathogen interactions and molecular epidemiology of malaria, Mycobacterium ulcerans disease (‘Buruli ulcer’) and epidemic meningococcal and pneumococcal meningitis

 Research Interest
 Network
Katharina Roltgen

Guest-Editor
Katharina Roltgen
Scientific Collaborator
Molecular Immunology Unit
Swiss Tropical and Public Health Institute
Basel
Switzerland

Biography :

Katharina Roltgen is a Scientific Collaborator and a post doctoral research fellow in Molecular Immunology Unit, Swiss Tropical and Public Health Institute,Basel, Switzerland. She received her PhD in Microbiiology from Swiss TPH. She also holds a position of Secretary of the Stop Buruli Consortium. Currently she is working under different projects related with Mycobacterium ulcerans.

 Biography
Research Interest :

Research focusses on development of point of care diagnostics for Buruli ulcer and Sero-epidemiological studies on the exposure of populations in endemic settings to Mycobacterium ulcerans.

 Research Interest
 Network
 
 
 
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