Enteropathic Spondyloarthritis

Crohn’s disease (CD) and ulcerative colitis (UC) are chronic relapsing inflammatory bowel diseases (IBDs) that can be associated with joint disease as an extra-intestinal manifestation. The relationship between gut and musculoskeletal inflammation has long been recognized. The arthritis related to IBD is called enteropathic (E) arthritis and belongs to the spondyloarthritis (SpA) spectrum of diseases, suggesting that the disease affects both the spine (Spondylo-) and the peripheral joints (-arthritis). The ESpA sub-group usually satisfies the criteria for SpA defined by the European Spondyloarthritis Study Group (ESSG), displaying low back pain and IBD. However, patients sometimes develop one or more SpA-related manifestations without fulfilling any of the SpA classification criteria. The first aim of this study was to assess the differences between AS and ESpA in terms of demographic (race, age at onset, gender) and clinical characteristics (symptoms at onset, delay in diagnosis, disease activity and extra-articular manifestations). The second aim was to assess the differences in musculoskeletal symptoms in AS and ESpA at onset and during the course of the disease and to determine what symptoms patients find most problematic.Final aim was to assess differences from the musculoskeletal system at presentation and during disease course between genders.

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Last date updated on April, 2024