The need for evaluating the immunizing potencies of rabies vaccines has been recognized since the early Pasteur days and practical standardized tests have been available and in use for over 20 years, many laboratories that produce the vaccines did not practice routine test on the potency of their products. both ERA and PV vaccinal strain based vaccines are free from any residual virus left after inactivation and no bacterial contamination during the process of production. The ERA and PV strain vaccines were effective at 8.32 IU/ml and 3.56 IU/ml, respectively. These crude vaccines fulfill the potency and safety requirement of rabies vaccine based on WHO recommendation. The vaccines can therefore be used for animal immunization, but further purification is required to be used for human.
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Last date updated on March, 2024