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Acute Kidney Failure

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Acute kidney failure

 Acute kidney failure occurs when your kidneys suddenly become unable to filter waste products from your blood. When your kidneys lose their filtering ability, dangerous levels of wastes may accumulate, and your blood's chemical makeup may get out of balance due to loss of electrolytes.

Typical symptoms

Nausea, Seizures or coma in severe cases, decreased urine output, normal Fluid retention, causing swelling in your legs, ankles or feet, Drowsiness, Shortness of breath, Fatigue, Confusion, Chest pain or pressure.

 

 
Acute kidney failure

 Dignosis

Urine output measurements, Urine tests, Blood tests, Imaging tests, Removing a sample of kidney tissue for testing.
 
Acute kidney failure

 Statistics

Acute renal failure (ARF) is an important complication after stem cell transplantation (SCT). We retrospectively analysed ARF in 363 recipients of allogeneic myeloablative SCT to identify incidence, risk factors, associated post-transplantation complications and mortality of ARF. ARF was graded as grade 0 (no ARF) to grade 3 (need for dialysis) according to creatinine, estimated glomerular filtration rate and need for dialysis. The incidence of severe renal failure (grades 2 and 3 combined) was 49.6% (180 of 363 patients). Hypertension present at SCT was identified as a risk factor for ARF (P=0.003). Despite this, survival of these patients was not different compared to patients without hypertension. Admission to the intensive care unit (ICU) was a post-transplantation complication significantly associated with ARF (P<0.001). Survival rate was highest in patients with ARF grade 0-1 and lowest in patients with grade 3 (P<0.001).

 

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