ISSN: 2155-6121
Journal of Allergy & Therapy
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
 
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Obesity and Asthma: Is Diet a Therapeutic Mean?

George Antonogeorgos and Demosthenes B. Panagiotakos*
Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
Corresponding Author : Demosthenes B. Panagiotakos
Associate Professor in Biostatistics-Epidemiology of Nutrition
Harokopio University of Athens
Department of Science of Dietetics-Nutrition, Athens, Greece
Tel: +30210 95 49 332
Fax: +30210 96 03 116
E-mail: d.b.panagiotakos@usa.net
Received March 20, 2012; Accepted March 26, 2012; Published March 29, 2012
Citation: Antonogeorgos G, Panagiotakos DB (2012) Obesity and Asthma: Is Diet a Therapeutic Mean? J Aller Ther 3:e105. doi: 10.4172/2155-6121.1000e105
Copyright: © 2012 Antonogeorgos G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Allergy & Therapy

Asthma and obesity have emerged as significant epidemics in the later decades, especially in the western world. The concomitant increasing trend in the prevalences of these two chronic conditions and the underlying inflammatory mechanisms that are implicated in their pathophysiology, has led researchers in the investigation for a possible causal link between them [1-2]. Several biochemical mediators associated with obesity, such as hormones (leptin) and cytokines (interleukin-6 and tumor necrosis factor-a) have been found elevated in asthmatic patients [3-4]. These mediators could potentially affect the airway smooth muscles and subsequently reduce the air flow, causing the dramatic arise of asthmatic symptoms such as cough, wheezing, shortness of breath and if untreated, respiratory distress and respiratory shock. Other possible pathway connecting asthma with obesity is through the respiratory mechanics and how they are affected especially by abdominal obesity [5]. Lastly, obesity had been found to be an independent predisposal factor for atopy, suggesting another link with asthma [6].
The low-grade inflammation observed in obesity and asthma could be associated with changes in common environmental factors such as diet. There are several proposed hypotheses relating similar factors in both diseases like decreases in antioxidants (vitamin C, vitamin E, carotenoids, Selenium, flavonoids and antioxidant-rich fruits), Poly-Unsaturated Fatty Acids (PUFAs) and Vitamin D blood concentrations [7-10]. However, most of the evidence in the literature is from observational and mainly cross-sectional and case-control studies, which are prone to several biases like measurement, selection and reverse causality bias.
Very small number of intervention studies, relatively to the large number of observational ones, has assessed the potentially therapeutic effect of the supplementation of antioxidants, PUFAs and Vitamin D with asthma. Vitamin C supplementations have been extensively studied in various doses but no sufficient evidence is found in order to have a place as an adjunct treatment against asthma [11]. PUFAs have been used as supplementation in randomized clinical trials but with also conflicting results [12]. Data for the potential protective role of Vitamin D are coming from observational studies solely, because the proposed therapeutic dose is too high (>2000 IU/day) and above the currently recommended dose ( 200 IU/day from infancy to 50 years) [13]. Regarding obesity, consumption of dried fruits, a source rich in antioxidants such as vitamin C and E, has been associated with reduced obesity in adults, but only through the mediation of improved diet quality [14].
However, human nutrition is a composite and should not be considered just as a daily nutrient replacement. The approach of assessing single nutrients or food items, instead of assessing dietary patterns could introduce some bias since we are not consuming isolated nutrients, but eat meals consisting of a variety of foods with complex combinations of them. A dietary pattern, the Mediterranean diet, has emerged lately in the literature as a protective factor against childhood and adult asthma, in addition to the established protective risk reduction in the cardiovascular diseases and obesity [15]. Mediterranean diet is characterized mainly by high consumption of fruits, vegetables, grains, legumes, low consumption of red meat and higher consumption of fish and white meat [16]. Mediterranean diet is also something more than just adequate intake of macro- or micronutrients, but it is also associated with a healthier lifestyle profile, expanding from increased physical activity to overall better nutritional knowledge. Adopting Mediterranean diet as a way-of-living could help restraining the inflammatory cascade of asthma, obesity and all the related complications better than it could be achieved by simply the replacement of the deficient nutrients.
Thus, the study of dietary patterns instead of isolated nutrients could offer better insights about the common role of diet in the etiopathology of obesity and asthma, providing us with new possible therapeutic means. A growing amount of evidence expands the well-known protective role of a specific dietary pattern, the Mediterranean diet, from the traditional field of obesity and cardiovascular diseases, to the new area of asthma. More intervention studies are needed in order to elucidate the beneficial effect of the Mediterranean diet in reducing the burden of these modern epidemics.
 
References
Select your language of interest to view the total content in your interested language
 
Share This Article
   
 
   
 
Relevant Topics
Disc Acrodermatitis
Disc Advance therapy for allergy rash
Disc Advanced Dermatitis Shampoos
Disc Advanced Eczema Creams
Disc Advanced Eczema Lotions
Disc Advances in Atopic Dermatitis Treatment
Disc Advances in Eczema Cure
Disc Advances in Perioral Dermatitis Treatment
Disc Allergen Immunotherapy
Disc Allergic Asthma
Disc Allergic Rhinitis
Disc Allergy
Disc Allergy Immunotherapy
Disc Aloe Vera Creams for Eczema
Disc Anaphylaxis
Disc Antihistamines
Disc Asthma
Disc Asthma Allergy Immunotherapy
Disc Baby Eczema
Disc Bladder Cancer Immunotherapy
Disc Breast Cancer Immunotherapy
Disc Bronchial Asthma
Disc Bronchoscopy
Disc Cancer Vaccines
Disc Cancer immunotherapy
Disc Cat Allergy Immunotherapy
Disc Cervical Cancer Immunotherapy
Disc Chicken pox Vaccines
Disc Childhood Vaccines
Disc Chronic Obstructive Pulmonary Disease
Disc Colon Cancer Immunotherapy
Disc Component Vaccines
Disc Contact Allergy
Disc Dermatitis
Disc Dust Allergy
Disc Ebola Vaccines
Disc Exfoliative Dermatitis
Disc Food Allergy
Disc Food Allergy Immunotherapy
Disc HIV Vaccines Research & Development
Disc Herbal Medicine for Eczema
Disc Human Papilloma Virus Vaccine
Disc Hydrocortisone Creams for Eczema
Disc Hypersensitivity
Disc Immunotherapeutic Products
Disc Immunotherapeutics
Disc Immunotherapy for Kidney Failure
Disc Lichenoids Dermatitis Treatment
Disc Lung Cancer Immunotherapy
Disc MMR Vaccines
Disc Melanoma Immunotherapy
Disc Nasal Allergy
Disc Natural Remedies for Dermatitis
Disc Neuro Dermatitis
Disc Nummular Dermatitis
Disc Ovarian Cancer Immunotherapy
Disc Pancreatic Cancer Immunotherapy
Disc Peanut Allergy Immunotherapy
Disc Pediatric Allergy and Immunology
Disc Polio Vaccines
Disc Pollen Allergy
Disc Preclinical Vaccine Studies
Disc Prostate Cancer Immunotherapy
Disc Pulmonary Alveolar Proteinosis
Disc Pulmonary Angiography
Disc Pulmonary Arterial Hypertension
Disc Pulmonary Aspergillosis
Disc Pulmonary Cancer
Disc Pulmonary Circulation
Disc Pulmonary Critical Care
Disc Pulmonary Dysplasia
Disc Pulmonary Effusion
Disc Pulmonary Eosinophilia
Disc Pulmonary Fibrosis
Disc Pulmonary Function Tests
Disc Pulmonary Hypoplasia
Disc Pulmonary Interstitial Fibrosis
Disc Pulmonary Lymphoma
Disc Pulmonary Neoplasm
Disc Pulmonary Oedema
Disc Pulmonary Parenchyma
Disc Pulmonary Thromboembolism
Disc Pulmonolgy
Disc Recombinant Vector Vaccines
Disc Regulatory and FDI Guidelines for Immunotherapeutics
Disc Respiratory Allergies
Disc Seborrheic Dermatitis
Disc Stasis Dermatitis
Disc Sublingual Immunotherapy
Disc Tdap Vaccines
Disc Tuberculosis Vaccines
Disc Vaccination
Disc Vaccine
Disc Vaccine Adjuvants
Disc Vaccine Regulatory Issues
Disc Vaccine Research & Development
Disc Vaccines Dermatology
Disc Vaccines Epidemiology
Disc Vaccines Immunology
Disc Veterinary Vaccines
 
Recommended Journals
Disc Medical Journal
Disc Dermatitis Journal
Disc Immunotherapy Journal
Disc Pulmonary Journal
Disc Vaccines Journal
  View More»
 
Recommended Conferences
Disc International Conference on Mucosal Immunology
Sep 26-28, 2016 Valencia, Spain
Disc International Conference on Autoimmunity
Oct 13-15, 2016 Manchester, UK
Disc 10th Nursing and Healthcare
December 05-07, 2016 Dallas, USA
 
Article Tools
Disc Export citation
Disc Share/Blog this article
 
Article usage
  Total views: 11146
  [From(publication date):
March-2012 - May 25, 2016]
  Breakdown by view type
  HTML page views : 7420
  PDF downloads :3726
 
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

 
OMICS International Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
 
 
OMICS International Conferences 2016-17
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings
 
 

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsinc.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsinc.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsinc.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsinc.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsinc.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsinc.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsinc.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsinc.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsinc.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsinc.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsinc.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsinc.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsinc.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsinc.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsinc.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsinc.com

1-702-714-7001 Extn: 9042

 
© 2008-2016 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version