Orthopedic & Muscular System: Current Research
Open Access
ISSN: 2161-0533
+44-20-4587-4809
ISSN: 2161-0533
+44-20-4587-4809
Mark Pitkin
Scientific Tracks Abstracts: Orthop Muscular Syst
Anisotropy is a fundamental characteristic of tissues regeneration replicating those in the tissues development. If design of an implant is not addressing it properly, the long-term bond between implant and the hosting tissues can-not be sustainable neither in total joint replacement, nor in direct skeletal attachment (DSA) of limb prostheses. Advantages in utilizing anisotropy of regeneration were demonstrated by preferred properties and orientation of the components of the Skin and Bone Integrated Pylon (SBIP) developed by Poly-Orth International, Sharon, MA. Besides optimizing porosity, pores size, particle size and volume fraction, we improved skin-implant and bone-implant interface via preferred orientation of the pylons�?? parts. Skin-implant interface: The SBIP is deeply porous perpendicular to the implant�??s longitudinal axis and also has perforations in the solid enforcing inserts. Skin cells can therefore penetrate the structure and grow throughout the entire volume of the implant in the �??natural�?� anisotropic direction of regeneration. That creates a skin seal, thus addressing the principal failure modes in existing percutaneous devices: skin regression, marsupialization, permigration, and avulsion. Bone-implant interface: Bone loss after implantation to the marrow canal is observed, and is caused by shield stresses. A variant of the SBIP and a new method of fixation are addressing this problem. Our SBIP-F pylon has side fins that are inserted into precut slots inside the cortical bone walls. The cut out bone activates an Ilizarov type distractional osteogenesis in which the regenerated bone has greater strength than the original bone.
Mark Pitkin has completed his PhD in Biomechanics at the Central Institute of Prosthetics Research in Moscow, Russia. He is Professor of Physical Medicine and Rehabilitation at the Tufts University School of Medicine, Boston, MA.