Anticariogenicity of casein-phosphopeptide with amorphous calcium-phosphate complexes
2nd International Conference and Exhibition on Dental & Oral Health
April 21-23, 2014 Crown Plaza Dubai, UAE

Shady Ahmed Moussa

Posters: Oral Health Dent Manag

Abstract:

Purpose: Study was evaluated the effect of Casein-Phosphopeptide with Amorphous-Calcium-Phosphate-complex (CPPACP) paste (Tooth-Mousse) and CPP-ACP complex with fluoride (MI paste) on cariogenic microflora system in children. Design: A total 120-children less than 15-years old with same oral hygiene-habits, participated in this study. They were divided into group(I) (n=20) who did not use CCP-ACP complexes and group(II) (n=100) that were divided into Subgroup(A) (n=50) who used (Tooth-Mousse) and Subgroup(B) (n=50) who used (MI-paste). They used CCP-ACP complexes as a topical application on teeth once daily for 60-seconds. Salivation of each child was stimulated by chewing a paraffin pellet for 5-minutes to collect 3ml of saliva that was divided into three equal parts. pH of saliva was measured by pH-meter using first part of collected saliva. Other parts of collected saliva were used for measuring the Streptococcus-mutans and lactobacilli count in saliva by means of selective culture media. Tests would be repeated after (7, 14, 30, 45) days of material using. Collected-data were statistical analysis by ANOVA test. Results: Salivary pH of both subgroups were significantly higher than in the group(I), P<0. 05. Streptococcus-mutans and Lactobacillus-acidophilus counts in both subgroups were significantly lower than the group(I), also while comparing subgroup(A) with subgroup(B) there was a significant decrease of bacterial counts in subgroup(B) more than subgroup(A), P<0. 05. Conclusion: Using CPP-ACP complexes increased salivary pH, which decreased the growth of Streptococcus-mutans and Lactobacillus-acidophilus. CPP-ACP containing fluoride is more beneficial than using CPP-ACP alone which attributed to inhibiting bacterial metabolism by fluoride effect.

Biography :

Shady A. Moussa had received his Doctor of Dental Surgery in 2000 from Cairo University (Egypt) and his postgraduate Master of pediatric dentistry and oral public health from Al-Azhar University in 2006 and his PhD in pediatric dentistry and oral public health Al-Azhar University (Egypt) in 2012. He is a lecture in Zagazig University, and currently working as consultant of pediatric dentistry in King Saud Hospital (Saudi Arabia). Dr. Shady published several articles in peer-reviewed journals.