Journal of Nanomedicine & Nanotechnology

Conjugates of DNA and Carbon nanotubes as nanobiosensors

10^th International Conference on Nanomedicine and Nanotechnology in Health Care

July 25-27, 2016 Bangkok, Thailand

Kazuo Umemura

Tokyo University of Science, Japan

Scientific Tracks Abstracts: J Nanomed Nanotechnol

Abstract:

Hybrids of DNA and single-walled carbon nanotubes (DNA-SWNT hybrids) are promising candidates for nanobiosensing devices. Although SWNTs are insoluble in water, mono-dispersed suspension of SWNTs are obtained when the surfaces of SWNTs are covered with DNA molecules. Then, use of the DNA-SWNT hybrids as a nanobiosensor is available by detecting minute changes of optical or electrical properties of SWNTs that are originated from some perturvaion such as injection of chemicals to the suspension. In this work, we systematically characterized DNA-SWNT hybrids by near-infrared (NIR) spectroscopy, fluorescent spectroscopy, photoluminescence, and atomic force microscopy. As a result, our data indicated that comibination of several optical measurements for similar samples was effective to obtain detailed information. For example, it was valuable to measure not only fluorescent spectra, but also NIR spectra of fluorescent labelled DNA-SWNT hybrids. NIR revealed unique responses even for fluorescent labelled samples. Our results involve helpful information to establish nanobiosensors using SWNTs.

Biography :

K Umemura has completed his PhD from Tokyo Institute of Technology. He is a full professor of Tokyo University of Science. He has published more than 50 papers in reviewed journals.

Email: meicun2006@163.com