Journal of Vaccines & Vaccination

Effi cacy of edwardsiella tarda, streptococcus iniae, strpetococcus parauberis, vibrio anguillarum, and tenacibaculum maritimum combined vaccine for cultured olive floundery

International Conference & Exhibition on Vaccines & Vaccination

22-24 Nov 2011 Philadelphia Airport Marriott, USA

Bokyu Kang

Scientific Tracks Abstracts: J Vaccines Vaccin

Abstract:

Edwardsiellosis, Streptococcosis and Vibriosis lead to extensive losses in aquaculture worldwide. Especially, Vibrio anguillarum, Streptococcus parauberis and Tenacibaculum maritimum are the most important causative agents among the bacterial pathogens in Olive fl ounder aquaculture and their infections increased steadily in Korea. Fish vaccine has been commercialized since 2006, however, only S. iniae and E.tarda vaccine is available for olive fl ounder at present in Korea. In this study, we evaluated the effi cacy of combined vaccine against E. tarda, S. iniae, S. parauberis, Vibrio anguillarum, and Tenacibaculum maritimum in cultured olive fl ounder. Th e fi sh divided fi ve groups for each bacterial pathogen. One hundred fi sh were injected intraperitoneally with 0.1mL per fi sh and the other one hundred were injected with sterile PBS with same method. At 3 weeks aft er vaccination, all fi sh were divided 5 groups evenly and challenged with 5 pathogenic bacteria strains including E. tarda, S. iniae, S. parauberis, Vibrio anguillarum, and Tenacibaculum maritimum. Relative percentage of survival (RPS) aft er challenge was calculated by checking the accumulated mortality of each group for 21 days. RPS was 80%, 85%, 75%, 90%, and 85% against E. tarda, S. iniae, S. parauberis, Vibrio anguillarum, and Tenacibaculum maritimum respectively. Th is study demonstrated that the combined vaccine induced protective effi cacy in olive fl ounders from virulent bacterial challenge.

Biography :

Bo-Kyu Kang has completed his Ph.D at the age of 35 years from Seoul National University. He is senior researcher of Research Unit of Green Cross Veterinary Products, which is animal vaccine company in Korea. He has published 27 papers in reputed journals and serving as a penal of Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries.