Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar

GET THE APP

Evaluation Of Affinity Capillary Electrophoresis For Ligand Binding Assays | 18689
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Evaluation of affinity capillary electrophoresis for ligand binding assays

5th International Conference and Exhibition on Analytical & Bioanalytical Techniques

Deia Abd El-Hady, Hassan M Albishri and Hermann Watzig

ScientificTracks Abstracts: J Anal Bioanal Tech

DOI: 10.4172/2155-9872.S1.017

Abstract
Process analytical technologies need precise and fast analytical tools especially in the early evaluation stage of drug discovery. Here, in the evaluation of ligand (drug) and receptor (plasma protein), affinity capillary electrophoresis (ACE) offers a lot of advantages including high separation efficiency, low sample volume, using of impure samples, ease and low cost of automation and ability to work under native physiological conditions. Furthermore, our recent published works suggested reduced experimental designs in which a single experiment could suffice. Then, the realistic duration of one binding-constant determination, including analysis and rinsing times, does not need to be more than a couple of hours, and this speed could be further multiplied by capillary arrays or miniaturized systems. Therefore, various analytical aspects of ACE including method development, and instrument qualification will be discussed. Precision certainly is a major parameter, to comply with acceptance criteria in quality control (QC), but also to investigate changes in biological systems. Further robustness, accuracy and selectivity are considered. In the case of high binding constants of the order of 10 5 per mol or higher, ACE is not applicable in its commonly used form. However, an advanced ACE version can also reliably detect high binding constants, which will be highlighted as an important feature.
Biography

Deia Abd El-Hady has completed his PhD at the age of 32 years from Assiut University joined with University of Bologna in Italy. He got postdoctoral grant by DAAD to study at Technical University of Braunschweig, Germany. Currently, he is an Associate Professor in King Abdulaziz University, Saudi Arabia. He has published more than 30 papers in reputed journals.

Top