Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Reach Us
+44 1223 790975
GET THE APP
Neuroinflammatory Markers In Alzheimer?s Disease And Dementia With Lewy Body | 21977
ISSN: 2161-0460
Journal of Alzheimers Disease & Parkinsonism
Open Access
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Introduction: Neuroinflammation is an important feature of Alzheimer?s disease (AD). However, little is known about
the inflammatory status of dementia with Lewy body (DLB), which has both AD (plaque and tangle) and alpha-synuclein
pathologies.
Methods: Levels of ?-amyloid (A?1-42), phosphorylated tau (pS396 tau) as well as inflammatory cytokines interleukin-10
(IL-10), IL-12, IL-13 and interferon ? (IFN- ?) in neocortical brain homogenates from aged controls, AD and DLB cases were
measured using ELISA and Luminex assays.
Results: AD and DLB both showed significant A?1-42 and p396 tau burden, at levels significantly higher than controls. In
contrast, only AD showed significantly higher levels of inflammatory markers, while neuroinflammatory markers are not
raised in DLB.
Discussion: Despite similar burden of AD pathology, DLB has a relatively mild neuroinflammatory response compared with
AD. The efficacy of anti-inflammatory therapeutic approaches may therefore be more limited in DLB.
Biography
Mitchell K P Lai received BSc from the University of Alberta, Canada in 1995 and PhD from the Department of Pharmacology, University of Sydney, Australia
in 2003. From 2003-2009, he was Principal Research Scientist with the Dept. of Clinical Research, Singapore General Hospital. First he joined in the National
University of Singapore (NUS) as a Research Fellow in 2010, then Research Assistant Professor in 2011 under the Memory, Aging and Cognition Centre. In
2012, he joined in NUS in the Dept. Pharmacology as an Assistant Professor. His research interests include neurochemistry of dementia, ?Omics? and molecular
mechanisms of neurodegeneration.
Relevant Topics
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals