Journal of Immunooncology

Immune Suppression

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Immune Suppression

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Immunosuppression involves an act that decreases the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Related Journals of Immunosuppression

Journal of Immunology, Nature Immunology, Nature Reviews Immunology, Annual Review of Immunology, Journal of Allergy and Clinical Immunology, Trends in Immunology, European Journal of Immunology

Immune Suppression

Expert PPTs

Speaker PPTs

  • Daniel S Peiffer
    Dietary consumption of black raspberries or their anthocyanin constituents alters innate immune cell trafficking in esophageal cancer
    | PDF Version
  • Ehab Kamal
    Apitherapy in immune mediated disorders
    PPT Version | PDF Version
  • Ricardo Rosales
    Vaccinia virus MVA as vector-vaccine strategy to modulate immune responses against Papillomavirus
    PPT Version | PDF Version
  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
    PPT Version | PDF Version
  • Michelle Tseng
    Innovative diagnostic approach in primary immune deficiencies
    PPT Version | PDF Version
  • Mona Mostafa Farid Ganem
    Bee venom acupuncture in different neurological illness and its immune modulation
    PPT Version | PDF Version
  • Sergey Suchkov
    Translational tools as applicable to autoimmune disorders: antibody-proteases as a generation of highly informative and unique biomarkers to monitor subclinical and clinical stages of demyelination in multiple sclerosis (MS)
    PPT Version | PDF Version
  • Maria da Graça Justo Araujo
    Fanconi anemia: Immune deficiency and susceptibility to cancer
    PPT Version | PDF Version
  • Filip Dubovsky
    Development of a passive RSV vaccine for infants as an alternative to maternal vaccination
    | PDF Version
  • Pieter Rousseau Fourie
    Immune Modulation in Children in South Africa: A Practical Approach
    PPT Version | PDF Version
  • Adebola Stephen Oluwatosin
    Anaerobic bacteriology of middle ear aspirate culture in the developing world: Possible role of immune-compromise in its etio-pathogenesis
    PPT Version | PDF Version
  • Francis Mussai
    Tumour arginine addiction subverts the anti-cancer immune response
    PPT Version | PDF Version
  • Hana Zelenkova
    Therapy with immune modulators (cyclosporine A) in dermatology (focusing on psoriasis, atopic eczema, allergic vasculitis, and chronic urticaria)
    PPT Version | PDF Version
  • Tahany H. Ayaad
    External immune stimulation and its impact on the honey bee Apis mellifera jementica in Saudi Arabia
    PPT Version | PDF Version
  • John S Pixley
    Generation of long-term human pancreatic islet cell activity in vivo by induction of immune tolerance to human stem cells
    PPT Version | PDF Version
  • Myron R Szewczuk
    Novel signaling paradigm regulating TOLL-like receptors on innate immune cells
    PPT Version | PDF Version
  • Dianne Lorton
    The Sympathetic Nervous System (SNS) A not so “sympathetic” regulator of immune function in autoimmune disease: RA as an example
    PPT Version | PDF Version
  • Vineeta Deshmukh
    Effectiveness of Ayurvedic treatment in alleviating side-effects of radiotherapy in oropharyngeal cancer patients and its relationship with improvement in immune status of the host
    PPT Version | PDF Version
  • Ruo-Pan Huang
    Cytokine arrays reveal “Black Ops” tactics of tumor-induced immunosuppression
    PPT Version | PDF Version
  • Ligia A. Pinto
    Immune Responses to Human Papillomavirus Vaccines: What We Have Learned
    PPT Version | PDF Version
  • Trevor Marshall
    Autoimmune inflammation and the human microbiome
    PPT Version | PDF Version
  • Xiaoni Zhang
    MiR-155 Modulates Morphine-induced Immunosuppression by Targeting SK3
    PPT Version | PDF Version
  • Ildikó Molnár
    Characteristics of allergy in autoimmune thyroid diseases
    PPT Version | PDF Version
  • Rafael Correa Rocha
    Immune mechanisms implicated in the tolerance induction to food allergens in children
    PPT Version | PDF Version
  • Loui Madakamutil
    Discovery of a small molecule inhibitor of Burton’s Tyrosine Kinase(BTK) for Loui Madakamutil, Ph.D 0 autoimmune diseases
    PPT Version | PDF Version
  • Marlous Dillingh
    Characterization of inflammation and immune cell modulation induced by lowdose LPS dose administration to healthy volunteers
    PPT Version | PDF Version
  • Igor Malyshev
    Physiological organization of immune response based on the homeostatic mechanism of matrix reprogramming: Implication in tumor and biotechnology
    PPT Version | PDF Version
  • John Pixley
    In utero transplantation (IUT) an experimental window into immune self Basic and applied implications
    PPT Version | PDF Version
  • Sherif Salah
    A novel approach to inhibit human immune deficiency virus (HIV-1) infection by actively neutralizing the antibodies of reverse transcriptase system
    PPT Version | PDF Version
  • Meg Mangin
    Clinical Evidence of Immune System Dysregulation Caused by Intracellular Infection
    PPT Version | PDF Version
  • Ahmed G. Hegazi
    Influence of honey in mice bearing Ehrlich carcinoma on immune status
    PPT Version | PDF Version
  • Estibalitz Laresgoiti-Servitje
    ROLE OF microRNASAND CD4+ T CELLSUBSETS IN THE REGULATIONOF THEIMMUNE SYSTEMDURINGPREGNANCY
    PPT Version | PDF Version
  • Nuha Nuwayri Salti
    Immune response in patients with cutaneous lesions caused by L. donovanisensolatoin Lebanon
    PPT Version | PDF Version
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