Natural Products are the substances made from the living organisms and originate in nature. It can be produced by naturally, total synthesis or semi-synthesis process which plays a vital role in the medicinal chemistry which deliver tricky targets throughout drug discovery process. It has been prolonged for commercial purposes for cosmetics, dietary supplements and foods created from natural resources. Natural products are the origin of the most complex and absorbing chemical structures and it represents natural biological activity, whether as individual compounds or as complex mixtures. Natural Products journal covers the fields of Herbal Medicine, Organic Chemistry and Pharmaceutical Science. Natural products are normally either of prebiotic source or originate from microbes, plants, or animal sources. As chemicals, natural products contain such classes of compounds as terpenoids, polyketides, amino acids, peptides, proteins, carbohydrates, lipids, nucleic acid bases, ribonucleic acid, deoxyribonucleic acid, and so forth. Natural products are not just coincidences or products of suitability of nature. Beyond probably they are a natural expression of the growth in complexity of organisms.