Pathways Databases Genes Cancer Prostate cancer KEGG CCNE2, FGFR1, HSP90AA1, IGF1, MAPK1, MAP2K1, NFKBIA, PIK3CD Pathways in cancer KEGG CTBP2, CCNE2, FGFR1, FZD1, HSP90AA1, IGF1, MAPK1, MAP2K1, NFKBIA, PIK3CD, STAT1, RALA Melanoma KEGG FGFR1, IGF1, MAPK1, MAP2K1, PIK3CD Pancreatic cancer KEGG MAPK1, MAP2K1, PIK3CD, STAT1, RALA Chronic myeloid leukemia KEGG CTBP2, MAPK1, MAP2K1, NFKBIA, PIK3CD Glioma KEGG IGF1, MAPK1, MAP2K1, PIK3CD Colorectal cancer KEGG FZD1, MAPK1, MAP2K1, PIK3CD Endometrial cancer KEGG MAPK1, MAP2K1, PIK3CD Non-small cell lung cancer KEGG MAPK1, MAP2K1, PIK3CD Acute myeloid leukemia KEGG MAPK1, MAP2K1, PIK3CD Renal cell carcinoma KEGG MAPK1, MAP2K1, PIK3CD Small cell lung cancer KEGG CCNE2,  NFKBIA, PIK3CD Proliferation and cell motility Focal adhesion KEGG CAV1, FLNC, IGF1, MAPK1, MAP2K1, PIK3CD, SPP1 VEGF signaling pathway KEGG HSPB1, MAPK1, MAP2K1, PIK3CD MAPK signaling pathway KEGG, BIOCARTA DUSP4, FGFR1, FLNC, HSPB1, MAPK1, MAP2K1, NR4A1, NFKBIA, STAT1 ErbB signaling pathway KEGG MAPK1, MAP2K1, PIK3CD Regulation of actin cytoskeleton KEGG FGFR1, MAPK1, MAP2K1, PIK3CD Pathogen recognition and phagocytosis Toll-like receptor signaling pathway KEGG MAPK1, MAP2K1, NFKBIA, PIK3CD, SPP1, STAT1 fMLP induced chemokine gene expression in HMC-1 cells BIOCARTA MAPK1, MAP2K1, NFKBIA T Cell Receptor Signaling Pathway KEGG MAPK1, MAP2K1, NFKBIA, PIK3CD Fc Epsilon Receptor I Signaling pathway KEGG MAPK1, MAP2K1, PIK3CD Fc gamma R-mediated phagocytosis KEGG MAPK1, MAP2K1, PIK3CD Other p53 signaling pathway KEGG CCNB1, CCNE2, IGF1, RRM2, SERPINE1, SFN Oocyte meiosis KEGG CCNB1, CCNE2, IGF1, MAPK1, MAP2K1, YWHAB, YWHAZ Cell cycle KEGG CDC6, CCNB1, CCNE2, SFN, YWHAB, YWHAZ Glutathione metabolism KEGG GGT1, GCLM, GSTM1, GSTM2, GSTM4, RRM2 Metabolism of xenobiotics by cytochrome P450 KEGG GSTM1, GSTM2, GSTM4 Drug metabolism KEGG GSTM1, GSTM2, GSTM4 Progesterone-mediated oocyte maturation KEGG CCNB1, HSP90AA1, IGF1, MAPK1, MAP2K1, PIK3CD Aldosterone-regulated sodium reabsorption KEGG IGF1, MAPK1, PIK3CD, SFN Neurotrophin signaling pathway KEGG MAPK1, MAP2K1, NFKBIA, PIK3CD, YWHAB, YWHAZ Cadmium induces DNA synthesis and proliferation in macrophages BIOCARTA MAPK1, MAP2K1, NFKBIA mTOR signaling pathway KEGG DDIT4, IGF1, MAPK1, PIK3CD NOD-like receptor signaling pathway KEGG CXCL1, HSP90AA1, MAPK1, NFKBIA B cell receptor signaling pathway KEGG MAPK1, MAP2K1, NFKBIA, PIK3CD Chemokine signaling pathway KEGG CXCL1, MAPK1, MAP2K1, NFKBIA, PIK3CD, STAT1 NFAT and Hypertrophy of the heart (Transcription in the broken heart) BIOCARTA IGF1, MAPK1, MAP2K1 Keratinocyte Differentiation BIOCARTA MAPK1, MAP2K1, NFKBIA Long-term depression KEGG IGF1, MAPK1, MAP2K1 Natural killer cell mediated cytotoxicity KEGG HLA-C, MAPK1, MAP2K1, PIK3CD Melanogenesis KEGG FZD1, MAPK1, MAP2K1 Insulin signaling pathway KEGG MAPK1, MAP2K1, PIK3CD

The 165 genes of interest were classified by DAVID into 42 different KEGG or Biocarta pathway maps

Table 1: Pathways retrieved by DAVID.