Figure 3: All-MCC (A), All-Accuracy (B), specificity (C) and sensitivity (D) of different predictors tested using the independent dataset. ‘**’ refers to the comparison of the All-Accuracy between PreLocABC and PCP-KNN, p<0.01; ‘*’ refers to the comparison of All-Accuracy of PreLocABC before and after the integration with PCPKNN, p<0.05. ‘mi’ refers to mitochondrion, ‘cy’ refers to cytoplasm, ‘er’ refers to endoplasmic reticulum, ‘ex’ refers to extracellular space, ‘go’ refers to Golgi apparatus, ‘ly’ refers to lysosome, ‘nu’ refers to nucleus, ‘pe’ refers to peroxisome and ‘pm’ refers to plasma membrane. The red underlines refer to the higher specificity and sensitivity of PreLocABC after being integrated with the mass-spectrum quantitative information of proteins than before.