Acc No

  Protein Name

      Biological Activity

C4PZD0

Glycogenin-related

Transferase activity, transferring glycosyl groups

C4Q7G8

ATP synthase beta subunit

Hydrogen ion transporting, ATP synthase activity

C4Q8H9

fructose 1,6-bisphosphate aldolase

Glycolysis, fructose-bisphosphate aldolase activity

C4QDJ7

Transketolase

Transferase, transketolase activity

C4QF57

Heat shock protein 70

Stress response, binding

C4QFH0

Retinaldehyde binding  related

Not available

C4Q7T0

Niemann-pick C1 (NPC1)

Hedgehog receptor activity  

C4QQR1

Major egg antigen (P40)

Egg-induced immunopathology

O96413

Polyubiquitin

ATP-dependent  degradation of cellular proteins

P09792

Glutathione S-transferase

Central role in the parasite detoxification system

P15964

Sm26/1 antigen

Role in increasing the solubility of haematin in the parasite gut

P35661

Sm26/2 antigen

Central role in the parasite detoxification system

P37227

Malate dehydrogenase

TCA cycle, malate metabolic process

P38658

ERP60

Cell redox homeostasis, protein disulfide isomerase activity

Q06814

Calreticulin

Molecular calcium-binding chaperone promoting folding

Q07167

Egg antigen SME16

Calcium ion binding

Q1WMM9

Venom allergen-like protein 3

Function unclear

Q26540

14-3-3 protein homolog 1

Capable of changing the conformation of its bound ligand

Q26582

Heat shock protein 86

Stress response

Q26595

Alpha tubulin

Microtubule-based movement, GTPase activity

Q27877

Enolase

Glycolysis, phosphopyruvate hydratase activity

Q2KMJ3

Secretory glycoprotein k5

Mmmunopathology of schistosomiasis

Q2Y2H5

 ribonuclease omega-1

Ribonuclease T2 activity

Q7Z1I4

Beta-tubulin

Microtubule-based movement, GTP binding

Q869D4

IL-4-inducing protein

Skewing the immune response toward Th2

Q86QQ6

Peptidylglycine alpha hydroxylating mono-oxygenase

Catecholamine metabolic process, copper ion binding

Q8T9N5

Thioredoxin

Cell redox homeostasiselectron carrier activity

Q94747

Elongation factor 1-alpha

Protein biosynthesis, translation elongation factor activity

Q962Y6

Thioredoxin glutathione reductase

Cell redox homeostasiss, electron carrier activity

Q9BMI9

Purine-nucleoside phosphorylase

 Nucleoside metabolic process

Q9XYR4

Phosphoenolpyruvate carboxykinase

Gluconeogenesis, GTP binding

C4QEC4

Peroxiredoxins

Cell redox homeostasis, oxidoreductase activity

Table 2: List of S. mansoni secreted proteins with probable biological activity.