Gene Symbol
Protein
Features
Fold- change
1
CLRN3
Clarin 3
Transmembrane protein not well characterized
13
2
SFRP4
Secreted frizzled-related protein 4
Overexpressed in colorectal cancers
11
3
SPOCK1
Testican-1
Plasma proteoglycan with unknown function
10
4
P4HA3
Procollagen-proline, 2-oxoglutarate 4-dioxygenase
Enzyme not well studied
9
5
TMEM158
Transmembrane protein 158
Associated with colorectal carcinogenesis
6
CHRDL2
Chordin-like 2
Overexpressed in breast, lung and colon tumors
7
GREM1
Gremlin 1
Overexpressed in epithelial tumors
8
ASPN
Asporin
Novel marker identified in breast cancer
ASH1L
Ash1 (absent, small, or homeotic)-like
Reported as therapeutic target in lung cancer
DOCK4
Dedicator of cytokinesis 4
Known to play crucial role in cell migration
HOXA11S
Homeo box A11, antisense
Non coding RNA not well characterized
12
PPAPDC1A
Phosphatidic acid phosphatase type 2 domain containing 1A
Upregulated in breast cancer
DPYSL3
Dihydropyrimidinase-like 3
Phosphoprotein involved in neuroblastoma
14
COMP
Cartilage oligomeric matrix protein
Overexpressed in oral submucous fibrosis
15
LPPR4
Plasticity related gene 1
Membrane protein not well characterized