Statistical technique

Proposed method

Technique

Relative relations between target and normal data

Supervised learning (RBF) by using correct and incorrect data

Analysis position

Each locus of mtDNA polymorphisms (independent position)

Entire loci of mtDNA polymorphisms (succesive positions)

Input (required data)

Target (individual cases) and control (normal data)

Correct (individual cases) and incorrect (others except correct)

Output (results)

Odds ratio or relative risk

Clusters with predictions

Analysis

Check odds ratio or relative risk at each position

Check individuals in clusters based on prediction probabilities