| Spectra assigned to the protein | NSAF | ||||||||||
| Down-regulated proteins | M W | M#1 10% LFD |
M#2 60% HFD |
M#3 10% LFD |
M#4 60% HFD |
M#5 10% LFD |
M#6 60% HFD |
M±SE 10% LFD |
M±SE 60% HFD |
 Ratio |
Function |
| Acyl-CoA desaturase 1 | 41kD | 3 | 0 | 3 | 0 | 9 | 1 | 6.08±4.42 | 0.43±0.74 | 0.07 | Lipogenesis |
| Acetyl-CoA carboxylase 1 | 265kD | 23 | 8 | 38 | 4 | 31 | 9 | 5.68±1.34 | 1.36±0.53* | 0.24 | Lipogenesis |
| Fatty acid synthase | 272kD | 158 | 51 | 214 | 43 | 215 | 76 | 35.39±6.32 | 10.70±3.56* | 0.30 | Lipogenesis |
| Pyruvate kinase isozymes R/L | 62kD | 32 | 9 | 35 | 11 | 34 | 11 | 26.68±1.45 | 8.52±1.07* | 0.32 | Glycolysis |
| NADP-dependent malic enzyme | 64kD | 16 | 8 | 11 | 5 | 25 | 7 | 13.43±5.95 | 5.33±1.24 | 0.40 | Lipogenesis |
| ATP-citrate synthase | 120kD | 23 | 10 | 33 | 12 | 29 | 11 | 11.60±2.01 | 4.68±0.43* | 0.40 | Lipogenesis |
| Ketohexokinase | 33kD | 24 | 8 | 17 | 7 | 22 | 12 | 31.33±5.85 | 14.01±4.53* | 0.45 | Glycolysis |
| Long-chain-fatty-acid-CoA ligase 5 | 76kD | 14 | 2 | 12 | 9 | 13 | 7 | 8.41±0.76 | 4.04±2.42 | 0.48 | Lipogenesis |
| Carbamoyl-phosphate synthase 1 | 165kD | 573 | 426 | 562 | 441 | 464 | 395 | 158.4±13.3 | 130.1±4.1* | 0.82 | Urea cycle |
| Data for NSAF are value x10,000.*p<0.05,vs.10%LFD. | |||||||||||
