Figure 1: Schematic of a panel of N-glycan “cryptic” antigens that are highly expressed by viruses and cancers. Expression of Neu5Ac, Tri/m-II, and Tri/m-Gn glyco-epitopes in glycoprotein Orosomucoid (OR), Asialo-OR (ASOR), and Agalacto-OR (AGOR) is readily detectable by lectin Sambucus nigra I (SNA), PHA-L, and GNA, respectively. GNA, 2G12, and TM10 recognize different glycoepitopes of oligomannoses expressed by cancer cells or viruses.