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Figure 2: Carbohydrate arrays recognize global similarity in antibody profiles among men with BPH and those with prostate cancer (PCa). Sera from 17 subjects with PCa and 12 with BPH were characterized using carbohydrate arrays. Array datasets were processed and statistically analyzed using SAS Institute’s JMP Genomics software package. Results are presented as overlay plots to illustrate the antibody profiles of each subject and to enable a visual comparison of the two groups, cancer (A) vs. BPH (B). Each dot in the plot is the mean value (IgG score) of triplicate array detection of a sample. The microarray datasets are presented in Supplemental Table 1. |