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Figure 5: Merged diagram of PI3K/Akt and SAPK/JNK. CXCL13 mediates differential phosphorylation of proteins (colored molecules) belonging to the PI3K/Akt and SAPK/JNK signaling pathways. The two canonical pathways were merged and overlaid with the analyzed microarray data from CXCL13-treated or untreated PC3 cells. Gray indicates no change in phosphorylation status, green indicates decreased phosphorylation, pink indicates baseline phosphorylation, and red indicates increased phosphorylation relative to baseline. |