Figure 1: Through the use of the Ingenuity Pathway Analysis software and interactive website, we linked 6 of the 8 liver proteins, and their pathways, which we found to be significantly altered by spaceflight (Table 1). These are all enzymes (CSP1, ALDOB, HSPD1, GNMT, MAT1A and RGN); these proteins in red or green are up or down regulated respectively, at least 1.5 fold over GRD values (except for CPS1 which is 1.2). All of the end-product proteins except PC (pyruvate carboxylase) are represented in Table 1.