| Variablea |
N Estb |
Average Estc |
Range Estd |
Average SEe |
| Binary: |
|
|
|
|
| HRK3 |
10 |
-0.1264 |
0.0644 |
0.0034 |
| HRK2 |
9 |
-0.0789 |
0.0284 |
0.0036 |
| HRK1 |
8 |
-0.1023 |
0.0422 |
0.0042 |
| P1 |
10 |
0.0783 |
0.0300 |
0.0030 |
| P2 |
10 |
-0.0719 |
0.0281 |
0.0030 |
| P3 |
10 |
-0.0798 |
0.0255 |
0.0030 |
| H3 |
8 |
0.0492 |
0.0445 |
0.0049 |
| Sulfur3 |
9 |
0.0825 |
0.1389 |
0.0112 |
| Sulfur2 |
8 |
0.0350f |
0.0316 |
0.0049 |
| Continuous: |
|
|
|
|
| Relative Fragment Size |
10 |
-0.6955 |
0.1748 |
0.0241 |
| Relative Fragment Mass |
10 |
0.8009 |
0.1693 |
0.0250 |
aVariables significant at p-value < 0.00005 in seven or more data sets and
minimum average estimates ≥ 0.05 log10 (ion intensity); Binary explanatory variable
nomenclature: X#: X denotes the residue (individual letter) or residue group (word
or group of letters corresponding to the residues), and # denotes the position of
the residue or group relative to the production ion fragmentation site (e.g. C2
denotes C located at the second to last position from the fragmentation terminus);
HRK: group of residues that have positive charge and are large and hydrophilic
(H, R, and K); P: denotes residue P that has neutral charge, is hydrophilic, imino
and tiny; N: denotes residue N that has neutral charge, is hydrophilic, amide and
small; H: denotes residue H that has a positive charge, is hydrophilic and large;
Sulfur: group of residues that have sulfur (C, and M); HRK: group of residues that
have positive charge, and are large and hydrophilic; Relative Fragment Size: ratio
between the fragment ion and peptide ion length; Relative Fragment Mass: ratio
between the fragment ion and peptide ion mass.
bNumber of training data sets significant at p-value < 0.00005.
cAverage of the log10 (intensity) estimates, adjusted for all other variables in the
model, across the number of data sets in which the variable appeared. For the
binary variables estimate is the difference in log10 (ion intensity) between presence
and absence of the residue or residue group at a specific location. For the
continuous variables estimate is the change in ion intensity per unity change in
the continuous variable.
dRange of the log10 (intensity) estimates across the number of data sets in which
the variable appeared.
eAverage standard error of the log10 (intensity) estimates across the number of data
sets in which the variable appeared.
f Borderline chemically significant. |
