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Figure 4: GO term enrichment analysis according to the ‘molecular function’ ontology. A target set of 190 proteins, closely associated with the T cell receptor was identified and compared to a background set of 972 proteins identified in T cells from human peripheral blood constituents [23], and data were visualized using the software GOrilla. GOrilla searches for enriched GO terms in two unranked lists of genes, the target and background set. The enrichment p-values are calculated using standard hyper geometric statistics. Graphics were modified from GOrilla. |