Figure 3a: Individual traces of bistability (left) and chaos (right) in a substrate-activated enzyme reaction. The top panels reflect ΔP (change in product concentration per time interval) over time; the bottom panels display the corresponding Fourier analyses. Y-axis, top panel=label×10-4, y- axis bottom panel=label×10-6 (k1=0.01, k2=0.1, k3=14.3, k4=1, k5=0.1, Etotal=0.5, with sinusoidal substrate input on the left panel and square substrate input on the right panel).