| Research Article |
Open Access |
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| Determination of Fragrance Allergens in Essential Oils and Evaluation of their in vitro Permeation from Essential Oil Formulations through Cultured Skin |
| Lai-Hao Wang*, Hung-Jiun Liu |
| Department of Applied Chemistry, Chia Nan University of Pharmacy and Science, Tainan 71743, Taiwan |
| *Corresponding author: |
Dr. Lai-Hao Wang,
Department of Applied Chemistry,
Chia Nan University of Pharmacy and Science,
Tainan 71743, Taiwan,
E-mail: e201466.wang@msa.hinet.net |
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| Received May 09, 2010; Accepted June 10, 2010; Published June 10, 2010 |
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| Citation: Wang LH, Liu HJ (2010) Determination of Fragrance Allergens in Essential Oils and Evaluation of their in vitro Permeation from Essential Oil Formulations through Cultured Skin. J Bioequiv Availab 2: 072-076. doi:10.4172/ jbb.1000034 |
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| Copyright: © 2010 Wang LH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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| Abstract |
| We developed a high-performance liquid chromatography method using fluorometric detection to simultaneously determine the allergens in fragrances, primarily structurally related allylbenzenes in essential oils. The effect of essential oil carriers—cloves, basil, and cinnamon—on the release and percutaneous absorption of the oils was studied in vitro using a cultured epidermal autograft membrane model. |
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