Cell type

HUVE C

MDA-MB-231

 

IC50 (μM)

Growth inhibition maximum (%)

IC50 (μM)

Growth inhibition maximum (%)

Free alendronate

-

8

120

50

γ-Fe2O3@alendronate nanocrystals

-

8

32

27

Free Alendronate-PEG

-

20

425

58

γ-Fe2O3@alendronate nanocrystals

 -

10

175

87
Table 2: Half maximal inhibitory concentration (IC50) and maximum percentage of cell inhibition (% Imax) for free Alendronate, γFe2O3@alendronate nanocrystals, free Alendronate-PEG and γFe2O3@alendronate-PEG nanocrystals with HUVEC, and MDA-MB-231 cell lines.