IFOBT IFOBT + TF (EITHER/or) P valuec Patients with changes in bowel habit (n=127)       All advanced adenomas and cancer(53) 　 　   Sensitivitya 30(56.6) 41(77.4) 0.023 Specificityb 37(50.0) 50(32.4) 0.030 Patients with bloody stool (n=89)       All advanced adenomas and cancer(40)       Sensitivitya 27(67.5) 36(90.0) 0.014 Specificityb 29(40.8) 35(28.6) 0.203 Patients with abdominal pain (n=74)       All advanced adenomas and cancer(22)       Sensitivitya 13(59.1) 20(90.9) 0.015 Specificityb 7(86.5) 24(53.8) 0.000 aSensitivity is the number of true positives relative to the number of persons with lesions. Numbers presented are the number of true positives per group. bSpecificity is the number of true negatives relative to the number of persons without lesions. Numbers presented are the number of false-positives per group. cTF combined with IFOBT (Either/or) vs IFOBT alone.

Table 6: Results of tests and subsequent colonoscopic findings in symptomatic population stratified by clinical features, n(%).