| Variables |
TT Genotype
n(%) |
TG Genotype
n(%) |
GG Genotype
n(%) |
T allele
frequency |
G allele frequency |
Chi-Square |
df |
P –value |
| Gender |
| Males |
26(23.2) |
65(58.0) |
21(18.8) |
0.52 |
0.48 |
5.3 |
2 |
0.06 |
| Females |
2(8.3) |
13(54.2) |
9(37.5) |
0.35 |
0.65 |
|
|
|
| Age at diagnosis (Years) |
| ≤45 |
3(13.6) |
15(68.2) |
4(18.2) |
0.48 |
0.52 |
|
|
0.56 |
| >45 |
25(21.9) |
63(55.3) |
26(22.8) |
0.5 |
0.5 |
|
|
|
| Histological Type |
| SCC |
19(24.1) |
41(51.8) |
19(24.1) |
0.5 |
0.5 |
2.41 |
2 |
0.29 |
| ADC |
9(15.8) |
37(64.9) |
11(19.2) |
0.48 |
0.52 |
|
|
|
| TNM Stage |
| Early Stage (I&II) |
10(19.6) |
36(70.6) |
5(9.8) |
0.55 |
0.45 |
8.09 |
2 |
0.01 |
| Advanced Stage
(III& IV) |
18(21.1) |
42(49.5) |
25(29.4) |
0.46 |
0.54 |
|
|
|
| Metastasis |
| Positive |
10(29.4) |
11(32.4) |
13(38.2) |
0.46 |
0.54 |
12.03 |
2 |
0.002 |
| Negative |
18(17.6) |
67(65.7) |
17(16.7) |
0.5 |
0.5 |
|
|
|
| Family History of any Cancer |
| Significant |
9(50.0) |
8(44.4) |
1(5.6) |
0.72 |
0.28 |
|
|
0.004 |
| Non Significant |
19(16.1) |
70(59.3) |
29(24.6) |
0.46 |
0.54 |
|
|
|
| Smoking Status |
|
|
| Non Smoker |
4(11.4) |
24(68.6) |
7(20.0) |
0.46 |
0.54 |
3.05 |
2 |
0.22 |
| Smokers |
24(23.7) |
54(53.5) |
23(22.8) |
0.5 |
0.5 |
|
|
|
| Smoking Level ( Pack Year) |
| Mild (≤10) |
0(0) |
9(90.0) |
1(10.0) |
045 |
0.55 |
10.3 |
4 |
0.036 |
| Moderate (≤40) |
10(22.2) |
27(60.0) |
8(17.8) |
0.52 |
0.48 |
|
|
|
| Heavy (>40) |
14(30.4) |
18( 39.0) |
14(30.4) |
0.5 |
0.5 |
|
|
|
| Smoking Type |
| Cigarette |
8(27.6) |
16(55.2 ) |
5(17.2) |
0.55 |
0.45 |
|
|
0.99 |
| Huka |
7(27.0) |
14(53.8) |
5(19.2) |
0.54 |
0.46 |
|
|
|
| Bidi |
3(23.0) |
8(61.6) |
2(15.4) |
0.54 |
0.46 |
|
|
|
| Cigarette+Bidi |
1(9.0) |
4(36.4) |
6(54.6) |
0.27 |
0.73 |
|
|
0.08 |
| Cigarette+Huka |
9(40.9) |
12(54.5) |
5(22.7) |
0.58 |
0.42 |
|
|
|
| Cytological Type |
| Squamous Cell Carcinoma |
| Well Differentiated |
11( 25.5) |
22(51.2) |
10(23.3) |
0.51 |
0.49 |
|
|
0.56 |
| Moderately Differentiated |
7(31.8 ) |
10(45.5) |
5(22.7) |
0.55 |
0.45 |
|
|
|
| Poorly Differentiated |
1(7.1 ) |
9(64.3 ) |
4(28.6) |
0.39 |
0.61 |
|
|
|
| Adenocarcinoma |
| Well Differentiated |
2(18.2) |
9(81.8 ) |
0(0 ) |
0.59 |
0.41 |
|
|
0.07 |
| Moderately Differentiated |
0(0) |
12(75.0) |
4(25.0) |
0.38 |
0.63 |
|
|
|
| Poorly Differentiated |
7(23.3) |
16(53.3) |
7(23.3) |
0.5 |
0.5 |
|
|
|
|
