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Figure 2: Combinational treatment of PQ1 and cisplatin has a synergistic effect on cell proliferation. T47D cells were treated with PQ1 and cisplatin alone and in combination. (A) Ki67 staining was used to examine cell proliferation under confocal microscope. Red indicates Ki67 and blue indicates nuclei stained by DAPI. (B) Percentages of Ki67 in treated cells were calculated and the results of each treatment were normalized to its controls. Data were obtained in three independent experiments and are represented as the mean ± S.E. * P-value is <0.05 compared to control. **P-value is <0.05 compared to cisplatin treatment. *** P-value is <0.05 compared to PQ1 treatment. |