Lane 1: TLR-3; Lane 2: TLR-4 and Lane 3: TLR-9; Lane 1: TLR-2; Lane 2: TLR-3; Lane 3: TLR-4; Lane 4: TLR-9. In the case of OC-3-VGH ovarian cancer cells, the expression of TLR-2 gene is too low to be quantitated. All data presented are statistically significant at P<0.01 except those labeled with * which are not statistically different from the negative control.

Figure 4: Changes in gene expressions of toll-like receptors (TLR-2, TLR-3, TLR-4 and TLR-9) of cultured OC-3-VGH ovarian cancer cells (A) and C-33A cervical cancer cells (B) upon treatments with 10 μg/ml each of goat anti-human IgG (GαHIgG) ( ), rabbit anti-T cell receptors β (RαTCRβ) ( ), mRP215 (), anti-TLR-4 (αTLR4) ( ) and LPS ( ). The negative control ( ) with normal mouse IgG (NMIgG) was adjusted to 100% in all cases.