Figure 2: Dense staining on Brca1 mutant mouse wholemount morphologically resembles multilocular brown adipose and stains positive for UCP1. H & E analysis showing the mammary fat pad of wildtype (a) and Brca1f/f;MMTV-Cre (b) postpubertal mice (6 months of age). Immunohistochemical detection of the brown adipose tissue marker, UCP1 in the mammary fat pad of wildtype (c) and Brca1f/f;MMTV-Cre (d) mice. Magnification, x 20.