Cells |
Treatment |
α (Gy-1)
control |
β (Gy-2)
control |
α -enhanc factor |
β -enhanc factor |
SW1573 ip |
sham |
0.21 ± 0.09 |
0.061 ± 0.016 |
|
|
|
1 μM cisplatin (1h) |
0.21 ± 0.08 |
0.072 ± 0.018 |
1.0 |
1.2 |
SW1573 dp |
sham |
0.10 ± 0.09 |
0.063 ± 0.016 |
|
|
|
1 μM cisplatin (1h) |
0.25 ± 0.09* |
0.077 ± 0.017 |
2.5 |
1.2 |
SW1573 ppi |
sham |
0.37 ± 0.12 |
0.014± 0.034 |
|
|
|
1 μM cisplatin
(cont) |
0.41 ± 0.08 |
0.019 ± 0.025 |
1.1 |
1.4 |
|
5 μM cisplatin
(cont) |
0.58 ± 0.20* |
0.030 ± 0.008* |
1.6 |
2.1 |
Siha ppi |
sham |
0.41 ± 0.04 |
0.01 ± 0.01 |
|
|
|
1 μM cisplatin (cont) |
0.81 ± 0.12* |
0.02 ± 0.02 |
2.0 |
2.0 |
Sham is radiation only; ip=immediately plated; dp=delayed plated; ppi=plated prior to irradiation. *Significant from sham p<0.05. |