Values are given as mean ±S.D. *♦○P<0.05; comparison within different genotypes was performed using one way Kruskal-Wallis, and then using Bonferroni post-hoc test. (○T-I-G vs C-I-G, ♦T-I-G vs T-D-G, *T-I-G vs C-I-A).Group 1: type 2 diabetes without nephropathy, Group 2: type 2 diabetes with nephropathy.

Figure 3: Percent change in UAE, serum creatinine and eGFR after 36 months of ACEI therapy among the three haplotypes (alleles of rs4311, I/D, and rs4343), stratified by the presence or absence of nephropathy.