Group 1 Group 2
  Before treatment After treatment P Before treatment After treatment P
eGFR (ml/min) 98.3 ± 19.8 128.1 ± 16.3 30.2 ± 19.1 0.02 29.8 ± 14.7 76.8 ± 24.6 36.1 ± 32.1 0.02
S.Creatinine(mg%) 0.9 ± 0.2 0.6 ± 0.1 -0.3 ± 0.2 0.03 4.1 ± 1.7 2.5 ± 1.4 -1.6 ± 1.6 0.01
UAE 70.1 ± 50.2 45.6 ± 42.3 -25.3 ± 48.8 0.009 1287.6 ± 135.5 771.3 ± 125.6 -514 ± 132.2 0.008
(p<0.05 is significant). The difference in delta values of means before and after treatment was done using Wilcoxon t-test. Group 1: type 2 diabetes without nephropathy, Group 2: type 2 diabetes with nephropathy.
Table 2: Change in eGFR, urinary albumin excretion rate (UAE), serum creatinine levels at baseline and the end of 36 months of active treatment.