Formulation Code

Production Yield (%)

Entrapment Efficiency* (%)

Drug Loading* (%)

Mean Particle Size*

Degree of Swelling*

Muco-adhesion (%)

IN1

79.2

75.74±0.50

7.57±0.05

362.45±4.12

1.63±0.012

98.5

IN2

75.3

72.94±0.61

7.29±0.06

334.57±6.24

1.61±0.011

98.2

IN3

77.1

68.34±0.90

6.84±0.09

355.12±5.69

1.57±0.010

94.1

IN4

74.4

67.70±0.56

6.77±0.06

326.48±4.38

1.56±0.010

93.8

IN5

86.4

70.27±0.61

7.03±0.06

310.58±7.17

1.16±0.009

85.3

IN6

82.9

68.94±0.64

6.89±0.06

274.25±4.43

1.10±0.008

84.7

IN7

85.3

64.47±0.70

6.45±0.07

301.31±5.83

1.03±0.008

81.6

IN8

82.1

62.00±0.72

6.20±0.06

262.59±5.18

0.98±0.008

82.5


*Mean ± S.D. (n=3)
Table 2: Characterization of microspheres.