Validation parameters PAR DPH PAP PLS PCR PLS PCR PLS PCR Mean ± SD 101.00± 1.20 100.61± 1.42 100.09± 0.75 100.40± 1.10 99.41± 1.16 99.51± 1.35 RMSEP 0.1025 0.1184 0.0106 0.1166 0.0836 0.00707 Predicted versus actual concentration plot   a-Slope b-Intercept c-Correlation coefficient (r) 1.0050 0.0100 0.9996 1.0106 -0.0139 0.9998 1.0011 -0.0187 0.9996 1.0029 0.0042 0.9994 0.9837 0.0637 0.9996 1.0189 -0.1065 0.9994

Table 3: Results of assay validation parameters of the proposed multivariate method for determination of Paracetamol, Diphenhydramine Hydrochloride and P-aminophenol.