Sr.
No. |
Exposure condition |
Time(h) |
Drug remained
(mg) |
% of drug
remained |
% R.S.D |
S.E. |
1 |
Photo degradation |
1.0 |
7.39 |
73.90 |
0.45 |
0.070 |
0.5 |
8.08 |
80.08 |
0.61 |
0.056 |
2 |
Oxidation |
|
3 % H2O2 |
1.0 |
4.77 |
47.70 |
0.342 |
0.49 |
30 % H2O2 |
1.0 |
1.50 |
15.00 |
0.293 |
0.007 |
3 |
Base degradation |
|
0.5 N NaOH |
1.0 |
1.09 |
10.09 |
0.128 |
0.063 |
0.1 N NaOH |
1.0 |
2.04 |
20.40 |
1.30 |
0.28 |
0.1 N NaOH |
0.6 |
3.12 |
31.20 |
2.00 |
0.17 |
0.1 N NaOH |
No heat |
8.62 |
86.26 |
0.483 |
0.18 |
4 |
Acid degradation |
|
|
0.5 N HCl |
1.0 |
3.068 |
30.68 |
0.12 |
0.04 |
0.1 N HCl |
1.0 |
4.919 |
49.19 |
0.806 |
0.13 |
5 |
Wet degradation |
1.0 |
10.02 |
100.02 |
2.00 |
0.014 |
6 |
Dry heat degradation |
1.0 |
10.04 |
100.40 |
0.85 |
0.037 |
|
