| Disintegrant |
F1 |
F2 |
F3 |
F4 |
F5 |
F6 |
F7 |
F8 |
F9 |
F10 |
F11 |
F12 |
F13 |
F14 |
F15 |
Cross
Carmellose |
3 |
9 |
18 |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| SSG |
- |
- |
- |
6 |
15 |
24 |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Crospovidone |
- |
- |
- |
- |
- |
- |
6 |
10.5 |
15 |
- |
- |
- |
- |
- |
- |
| XL 10 |
- |
- |
- |
- |
- |
- |
- |
- |
- |
3 |
6 |
9 |
- |
- |
- |
| KYRON |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
- |
1 |
8 |
15 |
| Responses |
| D T (Sec) |
65 |
56 |
39 |
49 |
45 |
36 |
24 |
12 |
9 |
52 |
43 |
31 |
121 |
78 |
19 |
| % Friability |
2.2% |
1.2% |
0.9% |
2.2% |
1.6% |
0.9% |
1.9% |
1.2% |
0.7% |
2.1% |
1.8% |
1.22% |
0.94% |
0.71% |
0.45% |
|
