Table 1

Concentration added to plasma (ng/ml)	Intra-day (n=6)			Inter-day (n=4)
Concentration added to plasma (ng/ml)	Mean measured concentration (ng/ml)	Accuracy (%)	RSD (%)	Mean measured concentration (ng/ml)	Accuracy (%)	RSD (%)
10	8.88 ± 0.72	88.8	8.11	8.95 ± 0.61	89.5	6.82
400	372.5 ± 8.46	93.1	2.27	377.6 ± 11.67	94.4	3.09
1000	875.5 ± 5.78	87.5	0.66	901.0 ± 6.33	90.1	0.70

Table 1: Intra-day and inter-day precision and accuracy of LC/MS determination of lappaconitine in rats plasma.