Parameters Variations Peak area %RSD Avg. %RSD Rt (min.) Capacity factor Theoretical plate
Flow rate ± 0.1ml/min 239521 0.21 0.35 7.51 1.201 3425
235684 0.32 7.31 1.425 3375
228796 0.54 7.19 0.962 3412
pH ± 0.20 245231 0.46 0.48 7.23 1.623 3422
241124 0.51 7.14 0.711 3463
Mobile phase ± 2 ml methanol 221124 0.31 0.29 7.12 1.322 3433
224565 0.27 7.54 1.121 3386
Table 5: Robustness data for Nisoldipine using HPLC system.